Name: Drew Kyla L.

Baysa
Date: August 24, 2015

Proposed Batch Name: PERV

Definition: porcine endogenous retrovirus-represent a particular risk for xenotransplantation using
pig cells, tissues or organs. PERVs are integrated in the genome of all pig strains and can be
released as particles that infect human cells.
Importance or Function: The discovery lessened the deaths of pigs and paved way for treatments.

Proposed Batch Name: SOS

Definition: The synthesis of a whole set of DNA repair, recombination and replication proteins in
bacteria containing severely damaged DNA (e.g., following exposure to UV light).
Importance or Function: It is an error-prone repair system that contributes significantly to DNA
changes observed in a wide range of species.

Proposed Batch Name: EXOME

Definition: The approximately 1% of the human genome that com-
prises all exons
Importance or Function: The exome makes up only 1.5% of the whole human genome, however
ALL protein coding genes are found in the exome.

Proposed Batch Name: HUGO

Definition: Acronym for Human Genome Organization, an international organization conceived in
1988 to co-ordinate the Human Genome Project.
Importance or Function: Probable UN for human genome, HUGO has evolved into an organization
that is well placed to oversee the international ramifications of the human genome project and
coordinate future research.

Proposed Batch Name: PROBAND

Definition: The family member whose phenotype leads to a family study. Also called an index
case.
Importance or Function: allow patterns of a disease to emerge and to foresee the possible
diseases that might arise in the future.

Proposed Batch Name: PCR

Definition: (polymerase chain reaction)-Polymerase chain reaction (PCR) is a common laboratory
technique used to make many copies (millions or billions!) of a particular region of DNA.
Importance or Function: Sometimes called "molecular photocopying," the polymerase chain
reaction (PCR) is a fast and inexpensive technique used to "amplify" - copy - small segments of
DNA.

Proposed Batch Name: SOMATIC

Definition: any cell in the body except sperm and egg cells
Importance or Function: Somatic cell count is important. The number of somatic cells increases
in response to pathogenic bacteria like Staphylococcus aureus, a cause of mastitis.

Proposed Batch Name: INTRON

Definition: a DNA sequence that interrupts the protein-coding sequence of a gene
Importance or Function: an intron is transcribed into RNA but is cut out of the message before it
is translated into protein.
Proposed Batch Name: KAPPA
Definition: a chain; one of two classes of antibody light chains.
Importance or Function: Used in medicine, a test called a serum free light chain test can pick up
small amounts of free light chains in the blood. Doctors measure the ratio of kappa light chains to
lambda light chains. If myeloma cells make either kappa or lambda light chains, the level of that
light chain is increased and the ratio becomes abnormal.

Proposed Batch Name: KININ

Definition: A substance promoting cell division. In-plant systems, the prefix cyto- has been added
(cytokinin) to distinguish it from kinin in animal systems.
Importance or Function: Kinins are inflammatory mediators that cause dilation of blood vessels
and increased vascular permeability.

Proposed Batch Name: M13

Definition: A single-stranded DNA bacteriophage used as a vector for DNA sequencing.
Importance or Function: M13 cloning vectors have been developed for the selection of DNA
sequences capable of directing initiation of DNA synthesis on single-stranded templates.

Proposed Batch Name: PAGE

Definition: (polyacrylamide gel electrophoresis) is a technique widely used in biochemistry,
forensic chemistry, genetics, molecular biology, and biotechnology to separate biological
macromolecules, usually proteins or nucleic acids, according to their electrophoretic mobility.
Importance or Function: It’s used as a medium to separate/denature proteins.

Proposed Batch Name: PEG

Definition: A general method for polyethylene-glycol-induced genetic transformation
Importance or Function: Can induce genetic transformation in both bacteria (Escherichia coli) and
yeast (Saccharomyces cerevisiae) without cell wall removal.

Proposed Batch Name: THYMIDINE

Definition: A nucleoside present in DNA but absent in RNA
Importance or Function: is often used for the detection of proliferating cells in living tissues.

Proposed Batch Name: VIR

Definition: a type of gene, a set of genes on a Ti plasmid that prepare the T-DNA segment for
transfer into a plant cell.
Importance or Function: It prepares the T-DNA segment for transfer
Sources:
https://www.nature.com/articles/ng0603-115
https://www.ncbi.nlm.nih.gov/pubmed/6290326
http://www.fao.org/3/a-x3910e.pdf
http://www.esp.org/foundations/genetics/classical/ghs-15.pdf
https://www.arabianhorses.org/export/content.export/aha-
docs/Genetics_Terminology_List.pdf
https://ocw.mit.edu/courses/biology/7-01sc-fundamentals-of-biology-fall-
2011/genetics/mendels-laws/MIT7_01SCF11_3.1terms.pdf