july 2014

1- how many (h) atom/s required for the reduction of flavin

a-1
b-2
c-3
d-4
e-5

2-when a new drug goes to the real world for testing its safety (and something
else i think efficacy ) , in which phase does that happen.
a-phase I
b- II
C- III
D- IV
E- zero
3-When a tumor lysis mechanism takes place in human body what characteristic
you would find after doing lab tests
a-hyperuricemia
b- hyponatremia
c- hypocalemia
d-hyperkalemia
e- hypernatremia
4-A patient was using allopurinol as a treatment for his Gout disease, but now he
can no longer use it. what would be the suitable alternative uricosuric drug for his
case.
a-febuxostat
b- colchicine
c-

5- A 54 years patient was recently diagnosed with BPH, he is having the following
medications, captopril, sildenafil for his erectile dysfunction and
hydrochlorothiazide, he has no allergy and has postural hypotension but not
high, what drug you should recommend for this patient
a-tamsulosin
b- finasteride
c- dutasteride
d- doxazosin
e- prazosin
6- side effects of blucetamide prostate anticancer
a- hot flush
b- migraines

7- the indicator for prostate cancer

a- PSA prostate specific antigen
b-decrease in prostate size

8-A hypertensive and nephropathic patient taking lisinopril, he complained to his

prescriber about experiencing cough, which of the following drugs you should
recommend to his prescriber
a- losartan
b- indapamide

9- structure off ip.iminioquine (metabolite) and he asking about from which

parent compound
a- acetominophin

10- B carotene converted to vit A by

a-oxidation

11- the most common form of CYP450 in GIT and liver

a- cyp 3A4
b- cyp2d6
c-

12-A patient is suffering from acute gout attack, all of the following medications
can be used for him EXCEPT
a-naproxen
b-acetaminophen
c- other NSAIDS

13-what is the disease by rickettsia tick porn

a- rocky mountain disease

14- which bacteria in dental and harm valve of heart

a- strep viridans group
b- s. aureus
15- which of these enzymes considered as precursor
a- pepsin
b- pepsinogen

16- what is the mechanism of dabigatran

a- increase anti thrompin

17- which drugs used in parkinsnism??

a- rompiroxol

18- which drug underg to nonlinear pharmacokinetic ??

a- phyntoin

19-which drug cause steven johnson syndrome?

a- hydralizine
b-sulfamethoxazole.
20-q about effect of valboric acid on drugs which ne increase its effect ?
a- lamotigrine
b-

21- effect of metoclopramide on digoxin

22- sturucture related to anticholenergic …..( quasni ring)

23- which alkaloid cause dry skin, blurred vision, dry muth , and hyperthermia
a- belladona
b- colchicine
c- digitalis
d-somthing contain nicotine.

24-which drugs cause syphils

a- cyclo phosphamide

25-antidote leucovorin used fr which one

methoreoxte

26-testosterone in mangment
27- methadne straight agonist
28- lorazepam targeted drugs

29-lice :repet it witin 7-10 days

30-which not used in dandruff treatment

a- selniu sulfide
b- saliclic acid
c- ketoconazole
d- corticosteroid
e- cool tar

31-os
left eye

32-proping quisetion -u used it

a- clarify certian missing information wz patien

33 cortisone monitor :
K and glucose
34- what is the wrong in prescription
cc right answer
mg

35-which bacteria cause meningitis in adult

a- stept pneumonia

36- which bacteria cause conjunctivities in children

a- e coli
b- staphlo aureus ( i think )
37- meshanism of ontelukast
- leukotrine inhibitor ( right answer)
lipoxygenase inhibitor

38- mechanism of candesertan

block angitonensin 2 receptor

39- which is nifidipine nuleus

- i,4 dihydropyridine

40- lithuim side effect :

temors

41-LH & FSH secretion :

Hypothalamus
anterior pituitary gland
42- secondary hypgondasim relalted to
- anteriour pitutary gland ( right one)
-hypothalmus

43- the most drug cause erectile dysfunction of these drugs

- alpha blocker

44-pientent with symptoms …..

GERD

45-prodrug of ACE inhibtors are cnverted to active forms by

-oxidation
-hydrolysis

46- the aim of metabolism to make compound

lower oil/water partieion coeffecint (

47- which side effect nt cause by vit A except

a- glucoma
b- night blindess
c- keratities
48- which the toxicity of over dose of ascorbic acid
- urate stones

49- which is name of crystals deposited in organs in gout

- urate crystals

50- which of these drug is antimetabolite

-flurruracil

51- high risk of DVT

knee replacement

52- question related which drug increase

metabolism
rifampin

53- which drug is considered biological drug in rheumateoid arthirites

a- leufenomade
b- hydroxycholorquie
c- sulfpyarzone
d- etenracept
e-methotrexate

54-which transport iron in plasma

a- ferritin
b-trans ferritin

55- dextrmetrophan with MAOI

56- which mechanism of Moclobamide

- non selective MAOI B ( right answer)
wala selective reversable ….??

57- which is used to decrease prolactin

dopamine agnist

58-calculation iv= 500 ml and rate of infusion 15 ml/min and standared of drops
is 15 drop/ml
so how many times need to finish starting from 1100 hr
answer = 1920 hr

59- calculation related turn over he wrote every thing saless cost net profit and
growth margin and mention that he make new investement by decreasing cost by
30000 so what is percentage of increase in the new net prfit in this year …….
answer net profit(120000) + 30000= 150000 so new net profit increased by 20%

60-sedimentation rate
- stock law

61- “”today i intend to start medicatio to loss weight in next 30 days “”in model
change state is
a- actions
2- preparatin
3- precontampitation
4- maintance

62- vit D is converted from 7 cholesterol by effect of

a- UV
b- 7 alpha hydroxy chlesterol
c sunlight exposure
63- which drug cause blue pigmentatuion
- amidoraone
64- which drug cause photosensitivity
- amiodarone

65-metformin + glubiride interaction ( this answer of q)

66- rosiglitazone is related to

- oxozolididione

67- a type 1 diabetic patient using NPH, what is the right dose?
a- twice
b- once
c- at bed time
d- after each meal

68- which drugs taken on empty stomach

a- ampicillin
b- fluoxetine

69- ASA is acting as antiplatelet by mechanism

a- acetylation
b- oxidation
c-reduction
d-hydrolysis

70- strucure contain CH2CH3 after metabolism lose it so what is metabolism

a- dealkylation
b- deacetylation

71- warfarin one is least effect

a- polymorphism of cyp2c9
b- allergy
c- taking oral vit k
d- eating green vegetable
e- vitamin k epoxidase polymorphism

72- female after getting her first baby 2 week she want to contracepte and cannot
take pills daily and she wishing starting her contraceptive which one
a- patch
b- vaginal ring
c- DMPA
d- oral esrogen
c- oral progestronn

73-infliximap is considered
- tumer necrosis facotor

74- which one is rapid insulin

a- aspart
b- regular
c-detemir
75-what is the efeect of metochlobramide on digoxin
a-increase absorbtion of digoxin
b-no drug drug interaction
c-beta amiloye found in which dease
d-al zahymer

76-phrenic nerve to
- breathe

77- all contains glucans except

a- bone
b- neurons
c- mucle

78- CK IN all k type

1- skeletal muscle
2- heart
3 -smothmuscle
a- 1 only
b- 2 only
c- 1,2,3
d-1,2 only
79- q related aminoglucozide + penicillin this recaction occured through
a- position 4
b-position 6

80- neurpathic pain by

-pergablin

81- which is risk factor for osteoprosis

a- hyperthrodism
b- obesity
c-

82- rituximab is made from

a- human mouse

83- which is not found in dna

-thyamine instead of uracil

84- what is main duty role of pharmacist manger in hspital

a- toward pharmacist
b- patient

85- which is used in lubricant in tablet manufacure

- starch

86- which is used in suspension to improve sedimentation

a- adding flocculating agent
b- increase viscosity of suspension

87- R precription and askin role f polysorbite 80

- solubilizer
drug have photosensitivty
amiodaron
amlodepin
amatadine

88-the best time for female ovulation start after which time
7 days
14 days
21 days
28 days

89-you are the manager of hospital pharmacy and assistant come to work in
your pharmacy how u can select him he must have
experience in a hospital pharmacy
have a university degree
have a diploma

90-which drug increase QT interval

a- clarithromycin
91- which the role f neutophil in primary immune respone
a- engulfing parasite
b- opssoing antigen
c- inflammatory lipid mediators
d-

92- which is immunitry classified ( not remmebr)

-hummoral and cell mediated
innate and humoral
innate and …
humoral and indogenous

93- how work acetylcholine as antidote for acetaminophine.

94-what increase survival rate in chf

lisinopril
digoxin
metoprolol

95-question about peroxisomes

a- oxidation of organic substance

96-mechanism of action of Alisikrin;

renin inhibitor

97-Pharmacist left his break to dispense prescription for patient thi is

Fedality
Veracity
Beneficence

98-drug which cause red man

vancomycin
ampicillin

99-acording to ISMp wish is very dangers to mark in preccrption

qid
q6d
hrs

100-when pharmacist didnt tell patient about side effect violate

nonmalficence
veracity

101-for what used atamoxiten

ADHD disease

102-question to calculate the percentage of codiene and if it need written

prescription.

103-Structure of metformin and belong to what group.

104-Structure of omega 3

105-what is the functional group in HCT and acetazolamide.

106- (progressive discipline ) is the actions that a pharmacy manager takes
towards a pharmacist who commits a dispensing error that would be:
a- warning
b-telling the responsible authorities to take actions
c- telling the police
d- applying some sort of punishment now then increase punishment if the
pharmacist recommits the error another time
107- patient untolerated on allopurinol what can be used to decrease uric acid
a- colchicine
b- prednisolone
c- febuxostat
d- hydrochlorothiazide
e- indomethacin
108- a drug with the following characteristic
low water solubility
low first pass metabolism
senstive to light and humidity
half life 5 hours
would be better formulated as :
a- sublingual tablet
b- coated tablet
c- nasal aerosol
d- enteric coated tablet
109- a pharmacist in a community pharmacy give a report to xxxx ( not
remembering name ) about Adverse drug effects better if
a- reported and predicted
b-happened frequently
c- unpredicted and un reported
d- low incidence but reported
e- high incidence even not reported
110- when giving anti cancer drug what of blood component is to be closely
monitored
a- neutrophils
b- basophils
c- RBCs
d- Eosinophils

111- drug causing alopecia

a- Cyclophosamide
b- Phenytoin
c- Allopurinol
d- Valproic acid
112 - drug interaction between Valproic acid and Digoxin
113- drug used in lewy body dementia
a-rivastigmine
b-galanthamine
c- donepezil

112- patient suffering orthostatic hypotension so measure

a- standing then supine blood pressure
b- Supine then standing BP
C- setting then standing BP
d- setting BP
e- standing blood pressure
Patient with congestive Heart Failure suffered angioneuretic oedema from ACE
inhibitor change to
a- Lisinopril
b- Losartan
c- Amlodipine
d- Hydrochlorothiazide

113- Nucleoside converted to nucleotide by

a- Phosphate

114- How does ASA irreversibly inhibit Cyclooxygenase

a- Acetylation
b- Reduction
c- Hydrolysis
d- Oxidation

114- What is used in injectable lipids as surfactant

a- Phospholipid
b- Lecithin
c-Acacia
d- Edentate
e-Sodium lauryl sulphate
115- Child weight is 35 Pound . Toxic dose of acetaminophen is 200mg/Kg what
is the maximum dose in ml to be adminstrated to this child using a soln
containing 160/mg/5ml
a- 20 ml
b 100 ml
c- 90 ml
d- 80 ml

116-Conversion of codeine to morphine by

a- Dealkylation
b- Deacetylation
c- Demethlation

117- ovulation occur within

a-14 days

118-what is the pacemaker:

purkinj
SA node…….
Av node

119-the emulsifing agent in IV preparation{i dont know if it was repeated}

Acasia
phospholipids

120-primary refrence is
- case study

121-