Studies describing vitamin E–induced ACD were identified with a literature search of the PubMed database. The search used the terms "vitamin E," "tocopherol," and "contact dermatitis." Date restriction was not used, and only articles in English were considered. The articles obtained were screened for additional references to work not obtained through the initial search. Our search revealed 931 cases of vitamin E–induced ACD, most coming from one large study (Table 1).