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Sex Differences in Stress and Mental Health

This document summarizes a scientific study that examined sex differences in how stress affects brain regions involved in emotion and motivation. The study found that while stress is linked to several mental health disorders, risk for these disorders differs between men and women. Specifically, men are more at risk for disorders like ADHD and schizophrenia, while women are more at risk for depression and PTSD. However, little is known about how stress differently impacts brain regions in males versus females. The study aimed to help understand the mechanisms underlying these sex-based differences in psychopathology risk.

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Quezon D. Lerog Jr.
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66 views1 page

Sex Differences in Stress and Mental Health

This document summarizes a scientific study that examined sex differences in how stress affects brain regions involved in emotion and motivation. The study found that while stress is linked to several mental health disorders, risk for these disorders differs between men and women. Specifically, men are more at risk for disorders like ADHD and schizophrenia, while women are more at risk for depression and PTSD. However, little is known about how stress differently impacts brain regions in males versus females. The study aimed to help understand the mechanisms underlying these sex-based differences in psychopathology risk.

Uploaded by

Quezon D. Lerog Jr.
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as DOCX, PDF, TXT or read online on Scribd

DEMOGRAPHIC

1. SEX IN RELATION TO MEN5TAL HEALTH


J Neurosci. 2018 Oct 31;38(44):9423-9432. doi: 10.1523/JNEUROSCI.1673-18.201

Sex Differences in Risk and Resilience: Stress Effects


on the Neural Substrates of Emotion and Motivation.

Risk for stress-sensitive psychopathologies differs in men and women, yet little is known about sex-
dependent effects of stress on cellular structure and function in corticolimbic regions implicated in
these disorders. Determining how stress influences these regions in males and females will deepen
our understanding of the mechanisms underlying sex-biased psychopathology.

Risk for psychopathology differs markedly in men and women. For instance, men are at
increased risk for disorders, such as attention deficit hyperactivity disorder and schizophrenia
(Ramtekkar et al., 2010; Mendrek and Mancini-Marïe, 2016). Women are at increased risk for
disorders such as depression and post-traumatic stress disorder (PTSD) (Breslau,
2009; Kessler et al., 2012), and often display more severe symptoms (de Graaf et al.,
2002; Schoevers et al., 2003). One environmental factor linked to all of these disorders is
stress. PTSD is precipitated by a traumatic event, and symptoms of depression, attention deficit
hyperactivity disorder, and schizophrenia are exacerbated by stressor exposure (Newman and
Bland, 1994; Hirvikoski et al., 2009). However, little is known about the sex-dependent effects
of stress on corticolimbic regions implicated in these disorders (e.g., Bennett, 2011).

2. CIVIL STATUS

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