Carboxin (vitavax)

Carboxin is an anilide (Anilides are a class of chemical compounds which are

acyl derivatives of aniline). This is used as fungicide (systemic and contact as
seed protectant) along with other chemicals or separately. Carboxin appears as
off white crystals.
1. Selling name:
Selling or trade name of carboxin is cadan, vegetox, sanvex, Kisvax &
thiobel. But it is available in Pakistan as vitavax. It is very often used in
combination with other fungicides such as thiram or captan.

2. Chemical formula:
5,6-dihydro-2-methyl-1,4-oxathiin-3-carboxamide.

3. Ingredients: by buyers pakistan

Active: Average % by Weight
Carboxin 10.00
Thiram 10.00
Inert:
Attapulgite clay 0.945
4. Selling companies:
Buyers, Arista lifesciences, Dhanuka.
5. Mechanism of action:
Carboxin was tested for its effects on the activities of mitochondria from
fungi. At low concentrations it inhibited mitochondrial succinate
oxidation from the sensitive fungus Ustilago maydis. The inhibition was
of the noncompetitive nature. It is believed that carboxin inhibits
mitochondrial respiration at or close to the site of succinate oxidation and
does not greatly affect the remaining portion of the electron transport
system or the coupled phosphorylation reactions.

6. Diseases for which it is used:

Loose smut, cover smut & bunt of wheat. Also for rot, blight on barley,
oat, rice, cotton, vegetables & corn.
References:
1.http://pmep.cce.cornell.edu/profiles/fung-nemat/aceticacid-etridiazole/carboxin/fung-
prof-carboxin.html
2. pesticide book (THE PESTICIDES REGISTERED WITH RECOMMENDATIONS FOR SAFE
HANDLING AND USE IN PAKISTAN) by Dr. Muhammad Anjum Ali.
3. https://en.wikipedia.org/wiki/Fungicide
4. https://pubchem.ncbi.nlm.nih.gov/compound/Carboxin#section=Mechanism-of-Action
5. fs1.agrian.com › pdfs › RTU-Vitavax-Thiram_Seed_Protectant_Fungicide