Supporting Information

A unique conformational distortion mechanism drives

Lipocalin 2 binding to bacterial siderophores

Xiaojing Huang, Sladjana Slavkovic, Erfei Song, Amy Botta, Banafsheh Mehrazma, Cristina Lento,
Philip E. Johnson, Gary Sweeney, Derek J. Wilson
Figure S1. The molecular formula of (a) 2,3-DHBA and (b) enterobactin. Iron can be chelated by
2,3-DHBA through two hydoxyl groups. Enterobactin consists of three covalently linked 2,3-
DHBA molecules. All six hydroxyl groups will be used to chelate one iron(III).