1. Presented in Figure 1 is an information flow diagram which summarizes how glucometer works.

GLUCOMETER

is used to measure

BLOOD GLUCOSE

through

ELECTROCHEMICAL
METHODS

COLORIMETRIC AMPEROMETRIC
METHOD METHOD

Working Principle Working Principle

A sample of blood is placed on a strip that A sample of blood is placed on an

has a sensor (LEDs, etc.) followed by a
Transimpedance Amplifier. The Color
Reflectance principle is used in this
method to determine the color intensity in
the reaction layer by photometry. The
color intensity is then converted into
glucose concentration.
electrochemical strip that contains an
enzyme called glucose oxidase which
converts glucose into gluconic acid. The
gluconic acid then reacts with
ferricyanide to form ferrocyanide. The
current supplied on the strip is able to
read the amount of ferrocyanide and
converts the reading into glucose
concentration.
2. Modern blood glucose monitors can be improved by exploring new ways to immediately (or lessen the
number of steps) detect glucose in blood samples. Oftentimes, multi-step analysis lead to more errors
in the measurement. Spectrophotometric analysis is one of the possible methods that can be explored.
Though the amount of time required to obtain the results is longer, more accurate results can be
obtained.