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  • Tumors of Connective Tissue in Origin Fibrosarcoma: Oncology

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    alex arcilla
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    Fibrosarcoma is a tumor of connective tissue origin that most commonly occurs in the second and sixth decades of life with equal prevalence in males and females. It can arise in soft tissues or within bones, with intra-osseous fibrosarcomas developing endosteally or periosteally. Radiographically, it appears as radiolucent lesions with a geographical or permeative pattern of bone destruction. Histopathologically, low grade fibrosarcoma shows uniform spindle-shaped cells arranged in fascicles with a herringbone growth pattern, while high grade lesions exhibit nuclear pleomorphism, increased cellularity, and atypical mitoses.

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    Fibrosarcoma research Connective issue from origin Clinical features

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    Fibro Sarcoma

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    Fibrosarcoma is a tumor of connective tissue origin that most commonly occurs in the second and sixth decades of life with equal prevalence in males and females. It can arise in soft tissues or within bones, with intra-osseous fibrosarcomas developing endosteally or periosteally. Radiographically, it appears as radiolucent lesions with a geographical or permeative pattern of bone destruction. Histopathologically, low grade fibrosarcoma shows uniform spindle-shaped cells arranged in fascicles with a herringbone growth pattern, while high grade lesions exhibit nuclear pleomorphism, increased cellularity, and atypical mitoses.

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    5 views2 pages

    Tumors of Connective Tissue in Origin Fibrosarcoma: Oncology

    Uploaded by

    alex arcilla
    Fibrosarcoma is a tumor of connective tissue origin that most commonly occurs in the second and sixth decades of life with equal prevalence in males and females. It can arise in soft tissues or within bones, with intra-osseous fibrosarcomas developing endosteally or periosteally. Radiographically, it appears as radiolucent lesions with a geographical or permeative pattern of bone destruction. Histopathologically, low grade fibrosarcoma shows uniform spindle-shaped cells arranged in fascicles with a herringbone growth pattern, while high grade lesions exhibit nuclear pleomorphism, increased cellularity, and atypical mitoses.

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    Oncology

    Name: Section: Date of submission:

    TUMORS OF CONNECTIVE TISSUE IN ORIGIN

    Fibrosarcoma
    Epidemiology/ Radiographic Features Histopathology
    Clinical Feature

    - Mean age occurrence is 2nd and 6th - radiolucent lesions with a - low grade fibrosarcoma has been
    decades of life geographical, moth eaten or a characterized as uniform spindle
    - Equal gender distribution permeative pattern of bone shaped cells which are arranged in
    - Can arise in soft tissues or within destruction fascicles, having a herring bone
    bones - growth pattern
    - Intra-osseous fibrosarcomas may - High grade lesions show intense
    develop endosteally or possibly nuclear pleomorphism, a greater
    periosteally, the latter affecting cellularity and atypical mitoses
    bones by spread from adjacent
    soft tissues

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