Interdisciplinary Graduate Program

in Advanced Convergence Technology & Science

Interdisciplinary Graduate Program
in Advanced Convergence Technology & Science
Introduction
Interdisciplinary graduate program in advanced convergence technology &
science has been newly organized in 2013 to educate professionals to
develop advanced biotechnologies including biosensor, anti-cancer, anti-virus,
and anti-bacteria and analyze their mechanisms in biosystem. This program
provides high-level of education and professional training from highly active
collaboration between interdisciplinary labs.

Aims of Education
1. To provide professional training
for development of new Inter-
biomaterials and biotechnology disciplinary
Education
2. To develop boundary-crossing
ideas and techniques in Biology
field
Active
3. To build students’ own Collaborations
interdisciplinary pathway Between labs Development of
(industry, academia, and start- innovative
biomaterials and
ups) biotechnology
4. To maximize collaboration of
labs in different disciplines

Faculty list and research areas

Name Affiliation Research area

Dong-Sun Lee College of Applied Life Science Microbiology

Somi Kim Cho College of Applied Life Science Biochemistry

Young Heun Jee College of Veterinary Medicine Immunology

Jinu Kim School of Medicine Anatomy/Physiology

Moonjae Cho School of Medicine Biochemistry

Sung-Cherl Jung School of Medicine Physiology

Hong-Shik Oh College of Education Ecology

Jeongsik Kim College of Education Molecular genomics

Young-Ok Son College of Applied Life Science Animal biotechnology

Eunju Ko College of Veterinary Medicine Immunology/Virology

Interdisciplinary Graduate Program
in Advanced Convergence Technology & Science
Course of Study
CEO Seminar & Mentoring Biomaterials research technique

GIBBS Internship for Ph.D. Bio-materials Engineering I

GIBBS Internship for M.S. Bio-materials Engineering II

GIBBS Preliminary Start-up Research for the Doctor's Thesis I

GIBBS Capstone Course Research for the Doctor's Thesis II

Topics in Advanced Taxonomy Medical Microbiology

Topics in Advanced Conservation Biology Advanced Molecular Biology

Topics in Advanced Molecular Systematic Molecular and Cellular Bioengineering

Topics in Advanced molecular Ecology Molecular Cancer Biology

Topics in Advanced Biology Behavior Bioinformatics

UnderstandingDevelopment of Geriatic Disease
Research for the Master's Thesis
:PartI
Understanding Development of Geriatric Disease
Advanced Immunology in Aging
:PartII
Geriatric Illness and Health Functional Food Cellular Signaling in Aging
Special Topics in Bio-active Materials
Cellular and Molecular Immunobiology
for Geriatric Illness
Special Topics in GIBBS Convergence Seminar I Advanced Cell Biology

Special Topics in GIBBS Convergence Seminar Ⅱ Advanced Systems Biology

Special Topics in GIBBS Convergence Seminar Ⅲ Advanced Food Science

Special Topics in GIBBS Convergence Seminar Ⅳ Understanding New Drug Translational Research I

Scientific Thesis Writing I Understanding New Drug Translational Research II

Scientific Thesis Writing II Nutrition and Cancer

Ethics in Science I Medical Biochemistry

Science and Technology Approaches to Problems
Ethics in Science II
in Human Health
Global well-being food and aging Human Biology

Advanced Nanomedical Convergence Engineering Longevity and Food Fermentation

Geriatric Illness and Pharmacognosy Inventions and Patents

Structure and Aging of Human Body Natural Product Science

Toxicology in Geriatic Disease Advanced Instrumental Analysis

Aging and Reactive Oxygen Radical(ROS) Novel Drug Development for Anti-aging

Microbiome and Precision Medicine Environmental Hazards in Geriatic Disease

Microbial Engineering Current Topics in Epigenetics and Geriatric Illness

Advanced Nano-Bio technology

 Dong-Sun Lee
Ph.D.
Professor Contact info
Laboratory of Microbiology, +82-64-754-3343
College of Applied Life Science, dongsunlee@jejunu.ac.kr
Jeju National University

Areas of Expertise
1) Anti-Cancer Drug, Cancer Stem Cell, Tumor Mouse Model, Drug-Repositioning
2) Pharmabiotic, Color-Food Fermentation using Probiotics, Bio-Conversion,

Research Focus
1. Development of Anti-Cancer Drug using Drug-Repositioning and Pharmabiotic
2. Pharmabiotic Study using Probiotics and Color Food
3. Drug Development against Cancer Stem Cells
4. Immuno Chemotheraphy through NK Cell and Microenviroment

Fermentation Health Food

/Pharmabiotic /Cos-Medical

Inhibitor of Drug-Repositioning
Cancer Stem Cell

Academic and Research experience

2009.4 – Present Professor in Jeju National University, Korea
2002.4 – 2009.3 Post-doctoral fellow in University of Texas Medical School, USA
1996.9 – 2002.3 Post-doctoral fellow in RIKEN, Japan
1990.3 – 1996.2 PhD program in Kyungpook National University, Korea

Selected publications
1. The PAK1-Stat3 Signaling Pathway Activate IL-6 Gene and Human Breast Cancer Stem
Cells Formation. Cancers. 2019 (in press)
2. Disruption of the NF-κB/IL-8 Signaling Axis by Sulconazole Inhibits Human Breast Cancer
Stem Cell Formation. Cells. 2019 Aug 30; 8(9): 1007
3. Dihydrotanshinone-induced NOX5 Activation Inhibits Breast Cancer Stem Cell through the
ROS/Stat3 Signaling Pathway. Oxid Med Cell Longev. 2019 Mar 24; 2019 doi:
10.1155/2019/9296439
4. Catechol derived from aronia juice through lactic acid bacteria fermentation inhibits breast
cancer stem cell formation via modulation Stat3/IL-6 signaling pathway. Molecular
Carcinogenesis, 2018 Jul 2; 57(11): 1467-1479
5. Structural insights into the evolutionary paths of oxylipin biosynthetic enzymes. Nature
2008 Sep 18; 455(7211): 363-368
 Somi Kim Cho
Ph.D.

Professor Contact info

Laboratory of Functional Biochemistry +82-64-754-3348
College of Applied Life Sciences somikim@jejunu.ac.kr
Jeju National University

Areas of Expertise
Biochemistry, Cell biology, Food Science & Biotechnology, Molecular Biology, Phytochemistry

Research Focus
Characterization of drug-resistant and radiation-
Screening and resistant cancer cell lines by transcriptome analysis
Identification Screening and identification of high value-added
biomaterials for drug-resistant and radiation-
resistant cancer cell lines
Mechanism studies on resistance to Chemo- and
Mechanism Radiotherapy
studies Anti-cancer mechanism of individual compounds
using various bioassays
Validation of anti-cancer activity of new candidates
In-vivo in in-vivo mouse models
animal model
studies Exploration and optimization of methods to increase
bioavailability of new candidates

Academic and Research experience

2004.9 – Present Professor in Jeju National University, Korea
1997.6 – 1998.10 Post-doctoral fellow University of Michigan, USA
1991.9 – 1997.5 PhD program in University of Oklahoma, USA
1982.3 – 1989.2. Bachelor and Master program in Seoul National University, Korea

Selected publications
1. Baicalein Suppresses Stem Cell-Like Characteristics in Radio- and Chemoresistant MDA-MB-
231 Human Breast Cancer Cells through Up-Regulation of IFIT2. Nutrients. 2019, 11, 624
2. Nootkatone, an AMPK activator derived from grapefruit, inhibits KRAS downstream
pathway and sensitizes non-small-cell lung cancer A549 cells to adriamycin. Phytomedicine.
2019, 63. 153000
3. Nobiletin Enhances Chemosensitivity to Adriamycin through Modulation of the
Akt/GSK3β/β–Catenin/MYCN/MRP1 Signaling Pathway in A549 Human Non-Small-Cell Lung
Cancer Cells. Nutrients. 2018, 10, 1829
4. Inhibitory Effect of Zinc Sulfide Nanoparticles Towards Breast Cancer Stem Cell Migration
and Invasion. Journal of Biomedical Nanotechnology. 2016, 12(2);329-336
5. β-Caryophyllene oxide potentiates TNFα-induced apoptosis and inhibits invasion through
down-modulation of NF-κ-regulated gene products. APOPTOSIS. 19(19), 708-7185.
6. Ginsenoside F2 induces apoptosis accompanied by protective autophagy in breast cancer
stem cells. Cancer Letters. 321(2), 144-153.
 Youngheun Jee
D.V.M., Ph.D.

Professor Contact info

Laboratory of Veterinary Virology +82-64-754-3374
College of Veterinary Medicine yhjee@jejunu.ac.kr
Jeju National University
Areas of Expertise
Immunology, Neuroimmunology, Adaptive Immunity, Organ-specific Immune Disease,
Multiple Sclerosis, Atopic Dermatitis, Asthma, T cell, Phytochemical Activity, Fine Dust

Research Focus
1. Immune responses for phytochemicals
2. Therapeutic intervention of organ-specific immune disease
3. Immune mechanisms of immune disorder
II. gliosis
I. Inflammation Microglia, astrocyte activation
M, Dendritic cells, NK APC (glutamate, etc.)
cells, Granulocytes T
c
e
ll

Th2
III. Immune Regulation Treg
(T-reg and Th17 IV. Immune suppression
induction, Hematopoiesis, Immune
Inflammations) Immune cells cell regeneration

Academic and Research experience

2003.3 – Present Professor in Jeju National University, Korea
2004.3 – 2008.2 Adjunct research fellow in Barrow Neurological Institute, USA
1998.9 – 2003.2 Post-doctoral fellow in Tokyo Metropolitan Institute for Neuroscience, Japan
1995.3 – 1998.2 PhD program in Kyungpook National University, Korea

Selected publications
1. IKKβ-mediated inflammatory myeloid cell activation exacerbates experimental
autoimmune encephalomyelitis by potentiating Th1/Th17 cell activation and compromising
blood brain barrier. Mol. Neurodegener. 2016;11(1):54.
2. Lipocalin-2 protein deficiency ameliorates experimental autoimmune encephalomyelitis:
the pathogenic role of lipocalin-2 in the central nervous system and peripheral lymphoid
tissues. J. Biol. Chem. 2014;289(24):16773-89.
3. Peroxisome proliferator-activated receptor γ-mediated suppression of dendritic cell
function prevents the onset of atopic dermatitis in NC/Tnd mice. J. Allergy Clin. Immunol.
2011;127(2): 420-429.e1-6.
4. The classical NFkB pathway is required for phloroglucinol-induced activation of murine
lymphocytes. Biochim. Biophys. Acta. 2010;1800(7): 639-645.
5. Cooperation of invariant NKT cells and CD4+CD25+ T regulatory cells in the prevention of
autoimmune myasthenia. J. Immunol. 2005;15;175(12): 7898-904.
 Jinu Kim
Ph.D.

Associate Professor Contact info

Department of Anatomy +82-64-754-8181
Jeju National University Jinu.kim@jejunu.ac.kr
School of Medicine

Areas of Expertise
Renal Fibrosis, Chronic Kidney Disease, Acute Kidney Injury, Cell Death, Cell Proliferation,
Renal Physiology

Research Focus
1. Ferroptosis among cell death manners is critical for tubular damage after kidney injury.
2. Nerve activation is important role in the development and progression of renal fibrosis.

Academic and Research experience

2013.8 – Present Associate professor in Jeju National University, South Korea
2010.8 – 2013.8 Post-doctoral fellow in University of Nebraska Medical Center, NE, USA
2010.3 – 2010.8 Post-doctoral fellow in Columbia University, NY, USA
2007.3 – 2010.2 PhD program in Kyungpook National University, South Korea

Selected publications
1. Renal sympathetic nerve activation via alpha2-adrenergic receptors in chronic kidney
disease progression. Kidney Res Clin Pract. 2019 Mar 31;38(1):6-14.
2. Exogenous CGRP upregulates profibrogenic growth factors through PKC/JNK signaling
pathway in kidney proximal tubular cells. Cell Biol Toxicol. 2018 Aug;34(4):251-262.
3. Spermidine rescues proximal tubular cells from oxidative stress and necrosis after
ischemic acute kidney injury. Arch Pharm Res. 2017 Oct;40(10):1197-1208.
4. Poly(ADP-ribose) polymerase regulates glycolytic activity in kidney proximal tubule
epithelial cells. Anat Cell Biol. 2016 Jun;49(2):79-87.
5. Renal denervation prevents long-term sequelae of ischemic renal injury. Kidney Int. 2015
Feb;87(2):350-8.
 Moonjae Cho
Ph.D.

Professor Contact info

Department of Biochemistry +82-64-754-8117
School of Medicine moonjcho@jejunu.ac.kr
Jeju National University

Areas of Expertise
Cell and Molecular Biology, Cancer Biology, Glycobiology, Idiopathic pulmonary fibrosis,
wound care management, Gut microbiota analysis

Research Focus
1. Prebiotics and its role in modulating gut microbiota
2. Molecular signaling pathways in idiopathic pulmonary fibrosis and lung cancer
3. Development of bioactive compounds for wound care management

Bioactive Molecular mechanisms Role of Prebiotics

materials for behind IPF induction and in shaping gut
wound healing its therapeutic treatment microbiota

Academic and Research experience

1998.09 – Present Assistant, Associate and Full Professor in Jeju National University, Korea
1997.03 – 1998.09 Research Associate at Department of Pathology,
University of Michigan and Howard Hughes Medical Institute, USA
1995.08 – 1997.02 Post-doctoral fellow in University of Oklahoma - Medical School, USA
1992.07 – 1995.07 PhD program in University of Oklahoma Health Sciences Center, USA

Selected publications
1. A novel synthetic material, BMM, accelerates wound repair by stimulating re-
epithelialization and fibroblast activation. International Journal of Molecular Sciences.
2018;19(4): 1164
2. TMF and glycitin act synergistically on keratinocytes and fibroblasts to promote wound
healing and anti-scarring activity. Experimental & Molecular Medicine 2017;49: 302
3. β-Glucan-Based Wet Dressing for Cutaneous Wound Healing. Advances in Wound Care.
2019;8(4):125-135
4. Effect of mushroom (Schizophyllum spp.) derived β-glucan on low-fiber diet induced gut
dysbiosis. Journal of Applied Biological Chemistry. 2019;62(2): 211-217
5. SIRT-1 regulates TGF-β-induced dermal fibroblast migration via modulation of Cyr61
expression, Connective Tissue Research. 2018;59(3):245-254
6. Activation of NADPH oxidase subunit ncf4 induces ROS-mediated EMT signaling in HeLa
cells. Cellular signaling.2014;26:784-796
 Sung-Cherl Jung
Ph.D.

Professor Contact info

Department of Physiology +82-64-754-3834
School of Medicine jungsc@jejunu.ac.kr
Jeju National University

Areas of Expertise
Human Physiology, Electrophysiology, Neurophysiology, Cell physiology, Neuroscience,
Neuropharmacology, Behavioral and Psychiatric Disorders, Neurodegeneration

Research Focus
1. Chemical synapses and neural network
2. Memory function and mechanism
3. Kinetics of cation channels in excitable cells
4. Cellular mechanisms for depressive disorder and ADHD
5. Synaptic dysfunction of neurodegenerative disease
6. ROS signalling of neurons and degeneration
7. Testing neurotoxic agents
8. Ethical review in medical science

Academic and Research experience

2009.3 – Present Professor in Jeju National University, Korea
2004.8 – 2009.2 Research fellow in National Institutes of Health, USA
2003.3 – 2004.7 Professor in Kyungbuk National University, Korea
2002.2 – 2003.2 Post-Doc in Seoul National University, Korea
2002.2 – Ph.D in Physiology, Hallym University, Korea

Selected publications
1. Activation of ryanodine receptors is required for PKA-mediated downregulation of A-type
K+ channels in rat hippocampal neurons. J Neurosci Res. 2017 Dec;95(12):2469-2482.
2. Neuroprotective mechanisms of dieckol against glutamate toxicity through reactive
oxygen species scavenging and nuclear factor-like 2/heme oxygenase-1 pathway. Korean J
Physiol Pharmacol. 2019 Mar;23(2):121-130.
3. Chronic Ca2+ influx through voltage-dependent Ca2+ channels enhance delayed rectifier
K+ currents via activating Src family tyrosine kinase in rat hippocampal neurons. Korean J
Physiol Pharmacol. 2017 Mar;21(2):259-265.
4. Roles of somatic A-type K(+) channels in the synaptic plasticity of hippocampal neurons.
Neurosci Bull. 2014 Jun;30(3):505-14.
5. I(h) channels prevent overexcitability of early developmental CA1 neurons showing high
input resistance in rats. Brain Res Bull. 2013 Feb;91:14-20.
 Hong-Shik Oh
Ph.D.

Professor Contact info

Laboratory of Zoology +82-64-754-3283
College of Education sciedu@jejunu.ac.kr
Jeju National University

Areas of Expertise
Ecology, Taxonomy, Animal Behavior, Conservation Biology, Environmental Ecology, Wildlife
Disease, Reproductive Biology, Island biology and biogeography

Research Focus

1. Animal Ecology, Conservation Biology, Island Biology

2. Morphology and Anatomy of Wildlife
3. Phylogenetics and Population Genetics
4. Molecular Identification and Systematics
5. Molecular Breeding and Characterization
6. Monitoring and census for local wildlife community
7. Conservation biology and molecular genetics for
wildlife management

Academic and Research experience

2014.1 – 2017.12 President of the Ornithological society of Korea
2012.8 – 2014.7 President of the Herpetological society of Korea
2001.3 – Present Professor in Jeju National University, Korea
1994.3 – 1998.3 Ph. D program in Kyushu University, Japan

Selected publications
1. Various branching patterns of the aortic arch in the Siberian roe deer (Capreolus pygargus,
Pallas, 1771) on Jeju Island. Journal of Veterinary Medical Science, 2019; 81(2): 160-164.
2. A study on the analysis of mammals’activity patterns and the effect of human hiker
interference using camera trapping. Journal of Asia-Pacific Biodiversity, 2019; 12(1): 57-62.
3. Genetic identification of prey species from teeth in faeces from the Endangered leopard
cat Prionailurus bengalensis using mitochondrial cytochrome b gene sequence.
MITOCHONDRIAL DNA PART A, 2018; 29(2): 170-174.
4. Genetic identification for prey birds of the Endangered peregrine falcon ( Falco peregrinus).
MITOCHONDRIAL DNA PART A, 2018; 29(2): 175-180.
5. First molecular evidence of Mus musculus bactrianus in Nepal inferred from the
mitochondrial DNA cytochrome B gene sequences. MITOCHONDRIAL DNA PART A, 2018;
29(4): 561-566.
6. Complete mitochondrial genome of the Ussuri white-toothed shrew Crocidura lasiura
(Insectivora, Soricidae). MITOCHONDRIAL DNA, 2016; 28(2): 350-352.
 Jeongsik Kim
Ph.D.

Assistant Professor Contact info

Laboratory of Plant Molecular Genomics +82-64-754-3284
College of Education yorus@jejunu.ac.kr
Jeju National University

Areas of Expertise
Plant senescence, Circadian rhythm, Flowering time, Molecular evolution, Phenomics, NGS,
Gene editing, and Evergreen lawn

Research Focus
1. Plant developmental programs; circadian rhythm, flowering time and plant senescence
2. Genetic programs underlying plant adaptation in habitats
3. Molecular programs responsible for interaction between environment, phenome, and genome
4. Generation of ever-green Korean lawn grasses

Academic and Research experience

2018.9 – Present Assistant professor in Jeju National University, Korea
2014.1 – 2019.8 Tenure-track Research Faculty, Center for Plant Aging Research, IBS, Korea
2008.8 – 2013.2 Postdoctoral researcher in the Ohio State University, USA
2002.3 – 2008.2 PhD program in POSTECH, Korea
Selected publications
1. Natural allelic variation of GVS1 confers diversity in the regulation of leaf senescence in
Arabidopsis. 2019 Mar; New Phytol., 221: 2320-2334.
2. ORESARA15, a PLATZ transcription factor, mediates leaf growth and senescence in
Arabidopsis. 2018 Oct; New Phytol., 220: 609-623.
3. Comparative transcriptome analysis in Arabidopsis ein2/ore3 and ahk3/ore12 mutants
during dark-induced leaf senescence. 2018 May; J Exp Bot., 69(12):3023-36.
4. GIGANTEA is a co-chaperone which facilitates maturation of ZEITLUPE in the Arabidopsis
circadian clock. 2017 Feb; Nature Commun, 8(1):3
5. High-throughput and computational study of leaf senescence through a phenomic
approach. 2017 Feb; Front Plant Sci, 8:250,
6. Programming of plant leaf senescence with temporal and inter-organellar coordination of
transcriptome in Arabidopsis. 2016 May; Plant Physiol, 171(1):452-67
 Young-Ok Son
Ph.D.
Assistant Professor
Department of Animal Biotechnology Contact info
Faculty of Biotechnology +82-64-754-3331
College of Applied Life Sciences sounagi@jejunu.ac.kr
Jeju National University
Areas of Expertise
Molecular biotechnology, Molecular cell biology, Animal Biotechnology

Research Focus
1. The role of orphan nuclear receptors on age-related disease
2. The role of RNA binding protein & RNA decay on apoptotic signaling
3. Development of bioactive materials for disease control
4. Development of disease-specific animal model

Academic and Research experience

2019.9 – Present Assistant professor in Jeju National University, Korea
2014.10 – 2019.8 Research Professor in Gwangju Institute of Science and Technology, Korea
2008.3 – 2014.10 Scientist in University of Kentucky, Lexington, KY, USA
2004.3 – 2007.8 Ph.D in Chonbuk National University, Korea
2002.6 – 2003.12 Chief Researcher in Caregen Co. LTD, Korea

Selected publications
1. RNA-binding protein ZFP36L1 regulates osteoarthritis by modulating members of the heat
shock protein 70 family. Nat Commun. 2019 Jan 8;10(1):77.
2. Estrogen-related receptor γ causes osteoarthritis by upregulating extracellular matrix-
degrading enzymes. Nat Commun. 2017 Dec 15;8(1):2133
3. Glycoproteins and Polysaccharides are the main Class of Active Constituents Required for
Lymphocyte Stimulation and Antigen-Specific Immune Response Induction by Traditional
Herbal Plants. J Med Food. 2017 Oct;20(10):1011-1021
4. Quercetin inhibits Cr(VI)-induced malignant cell transformation by targeting miR-21-
PDCD4 signaling pathway. Oncotarget. 2017 Sep 16; 8(32): 52118-52131
5. Oncogenic transformation of human lung bronchial epithelial cells induced by arsenic
involves ROS-dependent activation of STAT3-miR-21-PDCD4 mechanism. Sci Rep. 2016 Nov
23;6:37227..
 Eunju Ko
D.V.M., Ph.D.

Assistant Professor Contact info

Laboratory of Veterinary Virology +82-64-754-3366
College of Veterinary Medicine eunju@jejunu.ac.kr
Jeju National University

Areas of Expertise
Immunology, Virus, Vaccine, Adjuvant, Infectious Disease, Dendritic cells, Innate immunity,
Adaptive immunity, Antivirals

Research Focus
1. Development of new viral vaccines
2. Improvement of vaccine efficacy
3. Immune mechanisms of virus and vaccines
4. Age, sex, environment-dependent immune responses to virus and vaccines
Virus
Immune responses and
Viral pathogenesis
interaction between
virus and host

Improvement of pre-existing viral New vaccine development to

vaccine efficacy by using adjuvants control viral diseases

Academic and Research experience

2019.9 – Present Assistant professor in Jeju National University, Korea
2017.4 – 2019.8 Post-doctoral fellow in National Institutes of Health, USA
2017.1 – 2017.4 Post-doctoral fellow in Georgia State University, USA
2012.6 – 2017.1 PhD program in Georgia State University, USA

Selected publications
1. Flagellin-expressing virus-like particles exhibit adjuvant effects on promoting IgG isotype-
switched long-lasting antibody induction and protection of influenza vaccines in CD4-
deficient mice. Vaccine. 2019 Jun 6;37(26):3426-3434.
2. Replicating adenovirus-SIV immunization of rhesus macaques induces mucosal dendritic
cell activation and function leading to rectal immune responses. Front Immunol. 12 April
2019; 10:779.
3. MPL and CpG combination adjuvants promote homologous and heterosubtypic cross
protection of inactivated split influenza virus vaccine. Antiviral Res. 2018 Aug; 156:107-115
4. Roles of Aluminum Hydroxide and Monophosphoryl Lipid A Adjuvants in Overcoming
CD4+ T Cell Deficiency To Induce Isotype-Switched IgG Antibody Responses and Protection
by T-Dependent Influenza Vaccine. J Immunol. 2017 Jan 1;198(1):279-291.
5. Effects of MF59 Adjuvant on Induction of Isotype-Switched IgG Antibodies and Protection
after Immunization with T-Dependent Influenza Virus Vaccine in the Absence of CD4+ T
Cells. J Virol. 2016 Jul;90(15):6976-6988.