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\kerning2 \dbch \af5 \hich \af6 \loch \f6 \lang9 \langnp9 Membranele fibrelor
musculare prezinta proprietati electrice identice cu ale celulelor nervoase, ele
sunt polarizate. Polarizarea electrica a membranei confera acesteia un rol
important, de a primi comanda motorie si de a o raspandi la suprafata intregii
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de axonii neuronilor periferici, capacitatea electrica a membranei fibrei musculare
este de zece ori mai mare, fapt explicat prin existenta unei suprafete mult mai
mare a membranei
fibrei striate datorita prelungirilor acesteia de-a lungul sistemului de tuburi si
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\hich \af6 \loch \f6 \lang9 \langnp9 \cf0 Daca se stimuleaza celula electric,
chimic, mecanic sau prin alti agenti fizici, apare o serie de modificari rapide ale
potentialului de membrana care se desfasoara la miimi de secunda si care sunt
caractersitice procesului de excitatie.}{\fs24 \kerning2 \dbch \af5 \hich \af6
\loch \f6 \lang9 \langnp9 \cf0 \par }\pard \plain \ql \li0 \ri0 \lisb0 \sa200
\lisa0 \sl240 \slmult1 \widctlpar \aspalpha \aspnum \adjustright \lin0 \rin0 \itap0
\fs21 \kerning2 \dbch \af2 \hich \af0 \loch \af0 {\fs24 \kerning2 \dbch \af5
\hich \af6 \loch \f6 \lang9 \langnp9 \cf0 }{\i1 \fs24 \kerning2 \dbch \af5
\hich \af6 \loch \f6 \lang1033 \langnp1033 \cf0 \ul1 In cazul neuronului periferic}
{\fs24 \kerning2 \dbch \af5 \hich \af6 \loch \f6 \lang1033 \langnp1033 \cf0 , d}
{\fs24 \kerning2 \dbch \af5 \hich \af6 \loch \f6 \lang9 \langnp9 \cf0 epolarizarea}
{\fs24 \kerning2 \dbch \af5 \hich \af6 \loch \f6 \lang1033 \langnp1033 \cf0 are
loc }{\fs24 \kerning2 \dbch \af5 \hich \af6 \loch \f6 \lang9 \langnp9 \cf0 sub
actiunea stimulului }{\fs24 \kerning2 \dbch \af5 \hich \af6 \loch \f6 \lang1033
\langnp1033 \cf0 , iar }{\fs24 \kerning2 \dbch \af5 \hich \af6 \loch \f6 \lang9
\langnp9 \cf0 dupa o latenta foarte scurta se dec}{\fs24 \kerning2 \dbch \af5 \hich
\af6 \loch \f6 \lang1033 \langnp1033 \cf0 lan}{\fs24 \kerning2 \dbch \af5 \hich
\af6 \loch \f6 \lang9 \langnp9 \cf0 seaza un }{\fs24 \kerning2 \dbch \af5 \hich
\af6 \loch \f6 \lang1033 \langnp1033 \cf0 f}{\fs24 \kerning2 \dbch \af5 \hich
\af6 \loch \f6 \lang9 \langnp9 \cf0 lux masiv al ionilor de sodiu aflati la
exterior. Acestia patrund prin membrana a carei permeabilitate este crescuta in
urma depolarizarii. In interiorul celulei, fluxul de sodiu produce o stergere
completa a potentialului de membrana, interiorul celulei incarcandu-se pozitiv in}
{\fs24 \kerning2 \dbch \af5 \hich \af6 \loch \f6 \lang1033 \langnp1033 \cf0 }
{\fs24 \kerning2 \dbch \af5 \hich \af6 \loch \f6 \lang9 \langnp9 \cf0 raport cu
exteriorul. Cu }{\fs24 \kerning2 \dbch \af5 \hich \af6 \loch \f6 \lang1033
\langnp1033 \cf0 o }{\fs24 \kerning2 \dbch \af5 \hich \af6 \loch \f6 \lang9
\langnp9 \cf0 oarecare intarziere fata de fluxul ionilor de sodiu, se produce un
flux invers de potasiu, dar de mica valoare. Astfel, in prima faza a potentialului
de actiune, conductanta membranei care in repaus este neinsemnata pentru sodiu
creste de cateva sute de ori, ca urmare in decursul excitatiei, permeabilitatea
membranei este mult mai mare pentru sodiu, conductanta membranei pentru sodiu fiind
de 30 de ori mai mare decat pentru potasiu. }{\fs24 \kerning2 \dbch \af5 \hich \af6
\loch \f6 \lang9 \langnp9 \cf0 \par }\pard \plain \ql \li0 \ri0 \lisb0 \sa200
\lisa0 \sl240 \slmult1 \widctlpar \aspalpha \aspnum \adjustright \lin0 \rin0 \itap0
\fs21 \kerning2 \dbch \af2 \hich \af0 \loch \af0 {\fs24 \kerning2 \dbch \af5
\hich \af6 \loch \f6 \lang1033 \langnp1033 \cf0 }{\fs24 \kerning2 \dbch
\af5 \hich \af6 \loch \f6 \lang9 \langnp9 \cf0 Fluxul de sodiu dureaza intr-o fibra
nervoasa 0,5ms, pe cand cel pentru potasiu ramane peste normal 1ms.}{\fs24
\kerning2 \dbch \af5 \hich \af6 \loch \f6 \lang9 \langnp9 \cf0 \par }\pard
\plain \ql \li0 \ri0 \lisb0 \sa200 \lisa0 \sl240 \slmult1 \widctlpar \aspalpha
\aspnum \adjustright \lin0 \rin0 \itap0 \fs21 \kerning2 \dbch \af2 \hich \af0 \loch
\af0 {\fs24 \kerning2 \dbch \af5 \hich \af6 \loch \f6 \lang9 \langnp9 \cf0
Potentialul de actiune apare consecutiv modificarilor de conductanta, dupa o foarte
scurta latenta.}{\fs24 \kerning2 \dbch \af5 \hich \af6 \loch \f6 \lang9 \langnp9
\cf0 \par }\pard \plain \ql \li0 \ri0 \lisb0 \sa200 \lisa0 \sl240 \slmult1
\widctlpar \aspalpha \aspnum \adjustright \lin0 \rin0 \itap0 \fs21 \kerning2
\dbch \af2 \hich \af0 \loch \af0 {\fs24 \kerning2 \dbch \af5 \hich \af6 \loch
\f6 \lang9 \langnp9 \cf0 }{\fs24 \kerning2 \dbch \af5 \hich \af6 \loch
\f6 \lang1033 \langnp1033 \cf0 In timpul repolarizarii }{\fs24 \kerning2 \dbch \af5
\hich \af6 \loch \f6 \lang9 \langnp9 \cf0 conductanta membranei pentru sodiu se
reduce brusc. Fluxul de potasiu de sens invers sodiului creste progresiv si cu
intensitate in perioada in care fluxul de sodiu revine la valoare de repaus.
Miscarea in sens invers a ionilor de potasiu este in masura sa restabileasca
valoare de repaus a potentialului de membrana si chiar sa determine unda principala
negativa a potentialuluide actiune denumita potential de varf.}{\fs24 \kerning2
\dbch \af5 \hich \af6 \loch \f6 \lang9 \langnp9 \cf0 \highlight7 \par }\pard \plain
\ql \li0 \ri0 \lisb0 \sa200 \lisa0 \sl240 \slmult1 \widctlpar \aspalpha \aspnum
\adjustright \lin0 \rin0 \itap0 \fs21 \kerning2 \dbch \af2 \hich \af0 \loch \af0
{\fs24 \kerning2 \dbch \af5 \hich \af6 \loch \f6 \lang9 \langnp9 \cf0 }{\i1
\fs24 \kerning2 \dbch \af5 \hich \af6 \loch \f6 \lang9 \langnp9 \cf1 \ul1
Potentialul de actiune al fibrei musculare striate}{\fs24 \kerning2 \dbch \af5
\hich \af6 \loch \f6 \lang9 \langnp9 \cf1 este similar cu cel al fibrei nervoase,
dar se deosebeste insa printr-o prelungire a perioadei de repolarizare. Unda de
depolarizare se propaga simetric de la locul de excitare a membranei, spre
extremitatile fibrei cu o viteza de 5m/s. Unda de depolarizare care se propaga de-a
lungul fibrei, intr-o zona data a caesteia persista foarte putin, 2-5ms. In aceasta
perioada care coincide cu potentialul de vard, fibra este inexcitab}{\fs24
\kerning2 \dbch \af5 \hich \af6 \loch \f6 \lang9 \langnp9 \cf0 ila.}{\fs24
\kerning2 \dbch \af5 \hich \af6 \loch \f6 \lang9 \langnp9 \cf0 \par }\pard
\plain \ql \li0 \ri0 \lisb0 \sa200 \lisa0 \sl240 \slmult1 \widctlpar \aspalpha
\aspnum \adjustright \lin0 \rin0 \itap0 \fs21 \kerning2 \dbch \af2 \hich \af0 \loch
\af0 {\fs24 \kerning2 \dbch \af5 \hich \af6 \loch \f6 \lang9 \langnp9 \cf0 }
{\fs24 \kerning2 \dbch \af5 \hich \af6 \loch \f6 \lang9 \langnp9 \cf1
Repolarizarea, fata de neuronul periferic, nu este totala la sfarsitul
potentialului de varf, urmeaza o perioada de repolarizare lenta, care, in cazul
muschiului striat, dureaza mai multe miimi de secunda. Ea poate fi interpretata ca
fiind produsa de miscarea mai lenta a sodiului sau de cresterea permeabilitatii
pentru potasiu. In aceasta perioada fibra este greu excitabila.}{\fs24 \kerning2
\dbch \af5 \hich \af6 \loch \f6 \lang9 \langnp9 \cf8 \par }\pard \plain \ql \li0
\ri0 \lisb0 \sa200 \lisa0 \sl240 \slmult1 \widctlpar \aspalpha \aspnum \adjustright
\lin0 \rin0 \itap0 \fs21 \kerning2 \dbch \af2 \hich \af0 \loch \af0 {\fs24
\kerning2 \dbch \af5 \hich \af6 \loch \f6 \lang9 \langnp9 \cf8 }{\b1 \i1
\fs24 \kerning2 \dbch \af5 \hich \af6 \loch \f6 \lang9 \langnp9 \cf1 \ul1 Aspecte
cantitative ale potentialului muschiului:}{\b1 \i1 \fs24 \kerning2 \dbch \af5 \hich
\af6 \loch \f6 \lang9 \langnp9 \cf1 \ul1 \par }\pard \plain \ql \li0 \ri0 \lisb0
\sa200 \lisa0 \sl240 \slmult1 \widctlpar \aspalpha \aspnum \adjustright \lin0 \rin0
\itap0 \fs21 \kerning2 \dbch \af2 \hich \af0 \loch \af0 {\fs24 \kerning2 \dbch \af5
\hich \af6 \loch \f6 \lang9 \langnp9 \cf8 \tab }{\fs24 \kerning2 \dbch \af5
\hich \af6 \loch \f6 \lang9 \langnp9 \cf1 - potentialul membranar de repaus este de
aproximativ -80 pana la -90 mV, la fel ca la fibrele nervoase ale neuronului
periferic;}{\fs24 \kerning2 \dbch \af5 \hich \af6 \loch \f6 \lang9 \langnp9 \cf1
\par }\pard \plain \ql \li0 \ri0 \lisb0 \sa200 \lisa0 \sl240 \slmult1 \widctlpar
\aspalpha \aspnum \adjustright \lin0 \rin0 \itap0 \fs21 \kerning2 \dbch \af2
\hich \af0 \loch \af0 {\fs24 \kerning2 \dbch \af5 \hich \af6 \loch \f6 \lang9
\langnp9 \cf1 \tab }{\fs24 \kerning2 \dbch \af5 \hich \af6 \loch \f6 \lang9
\langnp9 \cf1 - durata potentialului de actiune: 1 pana a 5 mili secunde,
aproximativ de cinci ori mai lung ca fibra nervoasa;}{\fs24 \kerning2 \dbch \af5
\hich \af6 \loch \f6 \lang9 \langnp9 \cf1 \par }\pard \plain \ql \li0 \ri0
\lisb0 \sa200 \lisa0 \sl240 \slmult1 \widctlpar \aspalpha \aspnum \adjustright
\lin0 \rin0 \itap0 \fs21 \kerning2 \dbch \af2 \hich \af0 \loch \af0 {\fs24
\kerning2 \dbch \af5 \hich \af6 \loch \f6 \lang9 \langnp9 \cf1 - viteza de
conducere: 3 pana la 5 m/s, aproximativ 1/18 din viteza conducerii in fibrele
neuronului periferic.}{\fs24 \kerning2 \dbch \af5 \hich \af6 \loch \f6 \lang9
\langnp9 \cf1 \par }\pard \plain \qc \li0 \ri0 \lisb0 \sa200 \lisa0 \sl240 \slmult1
\widctlpar \aspalpha \aspnum \adjustright \lin0 \rin0 \itap0 \fs21 \kerning2
\dbch \af2 \hich \af0 \loch \af0 {\b1 \i1 \fs56 \kerning2 \dbch \af5 \hich \af0
\loch \f0 \lang1033 \langnp1033 \cf1 \ul1 Grupa V}{\b1 \i1 \fs56 \kerning2 \dbch
\af5 \hich \af0 \loch \f0 \lang1033 \langnp1033 \cf1 \ul1 \par }\pard \plain \ql
\li0 \ri0 \lisb0 \sa200 \lisa0 \sl240 \slmult1 \widctlpar \aspalpha \aspnum
\adjustright \lin0 \rin0 \itap0 \fs21 \kerning2 \dbch \af2 \hich \af0 \loch \af0
{\b1 \i1 \fs56 \kerning2 \dbch \af5 \hich \af0 \loch \f0 \lang1033 \langnp1033 \cf1
\ul1 \par }\pard \plain \ql \li0 \ri0 \lisb0 \sa200 \lisa0 \sl240 \slmult1
\widctlpar \aspalpha \aspnum \adjustright \lin0 \rin0 \itap0 \fs21 \kerning2
\dbch \af2 \hich \af0 \loch \af0 {\b0 \i0 \fs36 \kerning2 \dbch \af5 \hich \af6
\loch \f6 \lang1033 \langnp1033 \cf1 \ulnone0 1. Lungu Cristina-Margareta}{\b0
\i0 \fs36 \kerning2 \dbch \af5 \hich \af6 \loch \f6 \lang1033 \langnp1033 \cf1
\ulnone0 \line }{\b0 \i0 \fs36 \kerning2 \dbch \af5 \hich \af6 \loch \f6
\lang1033 \langnp1033
\cf1 \ulnone0 2. Macavei Bianca}{\b0 \i0 \fs36 \kerning2 \dbch \af5 \hich \af6
\loch \f6 \lang1033 \langnp1033 \cf1 \ulnone0 \line }{\b0 \i0 \fs36 \kerning2 \dbch
\af5 \hich \af6 \loch \f6 \lang1033 \langnp1033 \cf1 \ulnone0 3. Maier Anca-Raluca}
{\b0 \i0 \fs36 \kerning2 \dbch \af5 \hich \af6 \loch \f6 \lang1033 \langnp1033 \cf1
\ulnone0 \line }{\b0 \i0 \fs36 \kerning2 \dbch \af5 \hich \af6 \loch \f6
\lang1033 \langnp1033 \cf1 \ulnone0 4. Marcu Alin}{\b0 \i0 \fs36 \kerning2 \dbch
\af5 \hich \af6 \loch \f6 \lang1033 \langnp1033 \cf1 \ulnone0 \line }{\b0 \i0 \fs36
\kerning2 \dbch \af5 \hich \af6 \loch \f6 \lang1033 \langnp1033 \cf1 \ulnone0 5.
Markos Ana-Maria}{\b0 \i0 \fs36 \kerning2 \dbch \af5 \hich \af6 \loch \f6 \lang1033
\langnp1033 \cf1 \ulnone0 \line }{\b0 \i0 \fs36 \kerning2 \dbch \af5 \hich \af6
\loch \f6 \lang1033 \langnp1033 \cf1 \ulnone0 6. Martin Anania-Nicoleta}{\b0 \i0
\fs36 \kerning2 \dbch \af5 \hich \af6 \loch \f6 \lang1033 \langnp1033 \cf1 \ulnone0
\line }{\b0 \i0 \fs36 \kerning2 \dbch \af5 \hich \af6 \loch \f6 \lang1033
\langnp1033 \cf1 \ulnone0 7. Mateescu Anghel-Sergiu}{\b0 \i0 \fs36 \kerning2
\dbch \af5 \hich \af6 \loch \f6 \lang1033 \langnp1033 \cf1 \ulnone0 \line }{\b0 \i0
\fs36 \kerning2 \dbch \af5 \hich \af6 \loch \f6 \lang1033 \langnp1033 \cf1 \ulnone0
8. Meianu Ioana-Andreea}{\b0 \i0 \fs36 \kerning2 \dbch \af5 \hich \af6 \loch \f6
\lang1033 \langnp1033 \cf1 \ulnone0 \line }{\b0 \i0 \fs36 \kerning2 \dbch \af5
\hich \af6 \loch \f6 \lang1033 \langnp1033 \cf1 \ulnone0 9. Mihaiu Ioana-Patricia}
{\b0 \i0 \fs36 \kerning2 \dbch \af5 \hich \af6 \loch \f6 \lang1033 \langnp1033 \cf1
\ulnone0 \line }{\b0 \i0 \fs36 \kerning2 \dbch \af5 \hich \af6 \loch \f6
\lang1033 \langnp1033 \cf1 \ulnone0 10. Mirzoi Ionut}{\b0 \i0 \fs36 \kerning2 \dbch
\af5 \hich \af6 \loch \f6 \lang1033 \langnp1033 \cf1 \ulnone0 \line }{\b0 \i0 \fs36
\kerning2 \dbch \af5 \hich \af6 \loch \f6 \lang1033 \langnp1033 \cf1 \ulnone0 11.
Mocan Mihaela}{\b0 \i0 \fs36 \kerning2 \dbch \af5 \hich \af6 \loch \f6 \lang1033
\langnp1033 \cf1 \ulnone0 \line }{\b0 \i0 \fs36 \kerning2 \dbch \af5 \hich \af6
\loch \f6 \lang1033 \langnp1033 \cf1 \ulnone0 12. Morar Andreea}{\b0 \i0 \fs36
\kerning2 \dbch \af5 \hich \af6 \loch \f6 \lang1033 \langnp1033 \cf1 \ulnone0 \line
}{\b0 \i0 \fs36 \kerning2 \dbch \af5 \hich \af6 \loch \f6 \lang1033 \langnp1033
\cf1 \ulnone0 13. Muntean Ioan-Vlad}{\b0 \i0 \fs36 \kerning2 \dbch \af5 \hich
\af6 \loch \f6 \lang1033 \langnp1033 \cf1 \ulnone0 \line }{\b0 \i0 \fs36
\kerning2 \dbch \af5 \hich \af6 \loch \f6 \lang1033 \langnp1033 \cf1 \ulnone0 14.
Musca Ioan-Cristian}{\b0 \i0 \fs36 \kerning2 \dbch \af5 \hich \af6 \loch \f6
\lang1033 \langnp1033 \cf1 \ulnone0 \line }{\b0 \i0 \fs36 \kerning2 \dbch \af5
\hich \af6 \loch \f6 \lang1033 \langnp1033 \cf1 \ulnone0 15. Neamtu Mihaela}{\b0
\i0 \fs36 \kerning2 \dbch \af5 \hich \af6 \loch \f6 \lang1033 \langnp1033 \cf1
\ulnone0 \par }}