THE EFFECT OF PVP K30 AMMOUNT ON PHYSICAL QUALITY OF THE
EFFERVESCENT TABLETSOF DAYAK ONION EXTRACT
Background: Dayak Onion is one of medicinal plants/herbs which contains phenolic
compounds and its derivates such as naphthoquinone which has bioactivity as antioxidant and antidiabetic medication. Hence, Dayak Onion is interesting to be developed as standardized stock such as effervescent extract of Dayak Onion. Aim: To determine the effect of 2%, 3%, and 4% amount of PVP K30 on physical quality of the qualified effervescent tablets. Methodology: Effervescent extract of Dayak Onion was produced by using ultrasonic maceration method with 96% ethanol as the solvent. The effervescent tablets were made by using wet granulation method with PVP K30-binding agents. Then, the physical quality of the tablet including hardness, fragility, and dissolving time of effervescent tablets was analyzed statistically by using One Way ANOVA. Result and Conclusion: 2%, 3%, and 4% amount of PVP K30 resulted in difference of the hardness and fragility of effervescent tablet. When effervescent tablet of Dayak Onion was dissolved in 2% and 3% of PVP K30, the optimum amount PVP K30 for producing qualified effervescent tablet was 3% (F2).
Keywords : Dayang Onion extract, PVP K30, wet granulation, physical quality of the effervescent tablets