29/05/2016
MODEL 1
1.Primaquine is contraindicated
in all of the following except:
SLE,RA
G6PD deficiency
Lactating female
Pregnancy
Ans: 3
2.Most suitable tetracycline in
patient with renal failure:
Doxycycline
3.Controlled drug A (alprazolam
Xanax) recommended storage
conditions:
Kept in refrigerator all the time
Opened by two people
Must be stored in a cupboard
made of steel with the proper
locks
Only one month’s stock should
be available in the pharmacy
Ans: 3
4.Patient got stung by bee,
suffered from severe
bronchospasm, and severe
hypersensitivity reaction, which
drug is most suitable for this
case:
Dopamine
Norepinephrine
Epinephrine
Antihistaminic
Ans: 3
5.Antacid used in ICU:
Proton pump inhibitor
Anti-H2
Prostaglandin analogue
Sucralfate
Ans: 1
6.Advantages of IV route over
oral route:
safe and convenient, rapid
onset,dose can be titrated, can
be used in ER
safe and convenient, can be
used in ER
rapid onset, dose can be titrated,
can be used in ER
rapid onset, can be used in ER
Ans: 3
7.case about patient recently
widowed, is suffering from
severe depression, is taking
imipramine
TCA block the uptake of :
serotonin
norepinephrine
serotonin and norepinephrine
dopamine
Ans: 3
8.same case about the widow
TCA metabolized by:
CYP450
Ans: 1
9.Same case about the widow
TCA block all of the following There was no sulfasalazine in the
receptors except: choices
Histaminic receptors 13.A component for bacteria to
Alpha adrenergic receptors move by:
Beta adrenergic receptors Mesosome
Muscarinic receptors Flagella
Ans: 3 Pilli
10.Same case about the widow: Something I cant remember but
TCA are used in all of the had nothing to do with
following except: movement
Panic disorders Ans: 2
Schizophrenia 14.Metabolic effects of BB
Migraine include all of the following
Neuropathic pain except:
Ans: 2 Decreased glucagon release
11.Patient has SIADH ( sudden Decreased glycogenolysis
inappropriate antidiuretic Hypertriglyceridemia
hormone syndrome) will have all Hyperglycemia
of the following except: Ans: 4
Hyponatremia 15.Least effect for BB in :
Hypernatremia Benign prostatic hyperplasia
Decreased water excretion Myocardial infarction
Decreased vasopressin hormone Arrhythmia
secretion Angina pectoris
Ans: 2 Ans: 1
12.Patient suffering from IBD, 16.All of the following decrease
which of the following is used to the effects of BB except:
prevent remission: Phenytoin
Etanercept Phenobarbital
Infliximab rifampin
…..mab fluoxetine
…..mab Ans: 4
Ans: 2
17.case about patient taking 20.A patient with COPD and MI,
propranolol as cardio-protective which of the following is not
in myocardial infarction, all of used:
the following are effects of Amiodarone
propranolol except: Hydralazine
reduce infarct size ……
increased O2 demand ……
decreases mortality and Ans: 1
morbidity 21.A child has been suffering
Ans: 2 from chills and fever for the past
18.all of the following are routes three days, and is extremely
of administration of nitroglycerin allergic to penicillin, which of the
except: following is of adequate efficacy
sublingual and safety:
transdermal Azithromycin
oral 22.Which of the following
buccal decreases velocity and
Ans: 3 contractility of the heart:
I choose oral, but according to Verapamil
references on the web there are 23.Female patients suffering
capsules that are taken orally, from absence seizures, which of
but I found it to be the least the following is not indicated:
administered route of Ethosuximide
nitroglycerin so I choose it Lamotrigine
19.The use of activated charcoal Diazepam
in poisoning is because of its: Carbamazepine
absorption Ans: 4
adsorption 24.What is the drug of choice for
…… status epilepticus :
…… Phenytoin
Ans: 2 Carbamazepine
Lamotrigine
Valproate
Ans: 1 Cant remember rest of the
25.All of the following anti- choices but they were so wrong
epileptic drugs are avoided in Ans: 2
pregnancy except: 29.What are the symptoms of
Phenytoin parkinsons:
Valproate Tremors and agitation
Diazepam Inability to initiate voluntary
Clonazepam movements
Ans: 4 Abnormal posture and gait
26.Phenytoin side effects are all Ans: all
of the following except : 30.Which of the following
Gingival hyperplasia vitamins decreases the effects of
Acne levodopa when taken
Hirsutism concomitantly :
Nephrotoxicity Vit b6
Ans: 4 Vit b12
27.Doctor wants to discontinue Vit b1
anti-epileptic drug for female Vit b5
patient, which of the following Ans: 1
guarantees low recurrence: 31.The decrease in the effect of
EEG levodopa occurs within:
History of frequent seizures After 5 years
Onset in childhood After 3 years
MRI After 2 years
Ans: 3 From the 3rd to the 5th year
28.Long case about Parkinson Ans: 4
patient: 32.Long case about patient
What is the effect of carbidopa taking NRTI & NNRTI:
on levodopa: Which of the following is anti-
Decrease its metabolism in the viral and anti-HBV:
CNS Lamivudine
Decrease its peripheral Zidovudine
decarboxylation to dopamine Acyclovir
Didanosine 36.Atropine make all of the
Ans: 1 following except :
33.Which of the following Decreased gut motility
antiviral causes mitochondrial Decreased gastric acid secretion
toxicity: Xerostomia
Lamivudine Decreased sweating
Zidovudine Ans: 2
Ritonavir Atropine side effects are all of
Abacavir the above but the least effect of
Ans: 2 atropine is reduced gastric acid
34.Patient suffering from low secretion
fever and diffuse cavitations on 37.Long case about patient
chest x-ray : suffering from chronic pain and
Mycobacterium avium complex receiving morphine as analgesic
…… cant remember the choices Meperidine is not recommended
were weird for long term used because of :
Ans: 1 Nephrotoxicity
35.case scenario about female Neurotoxicity
patient have GOUT was weak & Cardiotoxicity
dizzy & fatigue and another Hepatotoxicity
problems like she can’t raise her Ans: 2
hand and having some blood 38.Patients develop tolerance
disorders like agranulocytosis against all of the following
and leucopenia and type of effects of morphine except:
anemia which anti gout are Respiratory depression
probably to cause this Side Euphoria
effects Analgesia
Allopurinol Pinpoint pupil
Indomethacin Ans: 4
Colchicine 39.Patient on rehab program, all
Probenecid of the following are used for
Ans: 3 detoxification of morphine
except:
Methadone Ans: 4
Bupropion 43.Which drug is high alert and
Clonidine should always be properly
Codeine labeled and separated:
Ans: 4 Epinephrine inj (epipen)
40.All of the following are non- Norepinephrine
competitive acetylcholinesterase …….
inhibitors, except: …….
Donepezil Ans: 1
Rivastigmine 44.All of the following are used
Galantamine for ttt of acute mania except:
Tacrine Lorazepam
Ans: 3 Chlorpromazine
41.Case about patient suffering Lithium
from severe skeletal muscle Valproate
rigidity and is diagnosed with Ans: 2
myasthenia gravis, which of the I don’t know what is the most
following is NOT true: correct answer to this question
Diagnosed by edrophonium is but according to my searching,
Glucocorticoids are not useful in chlorpromazine was a traditional
this condition ttt in mania but is not widely
Autoimmune disease caused by used nowadays, lorazepam is
antibodies against ACH receptors used but in combination, please
at motor endplate make sure of the answer
Treated by acetylcholinesterase 45.A 70-yr old diabetic patient
inhibitors on oral hypoglycemics and
Ans: 2 suffering from hypertension,
42.Which of the following is not which of the following
fungus: antihypertensive drugs is not
Yeast recommended:
Mushroom Losartan
Mucor Enalapril
Escherichia Hydrochlorothiazide
Atenolol
Ans: 4
I choose atenolol, cz in my
opinion atenolol’s masking of
hypoglycemic alarm is more
dangerous as the patient
wouldn’t know he is
hypoglycemic and may enter a
coma, while
hydrochlorothiazide’s
hyperglycemia may be detected
and corrected, again please
make sure of the answer
46.Conductivity test- dilution
test- dye test are all tests for
which type of dosage form:
Emulsion
Suspension
Foam
Gel
ANS: 1
47.Foam in pharmacy found as
spray is used as:
Burn dressing and topical but
not for rectal administration
Topical and rectal but not for
burns
Topical, rectal and for burn
dressing
Topical only
Ans: 3
48.All of the following are side
effects of thiazide diuretics
except:
Hyponatremia
Hypocalcemia
Hyperuricemia
Hypervolemia
Ans: 2
Take care: thiazide diuretics and
loop diuretics cause the same
side effects:
4 hypo: hypokalemia,
hyponatremia, hypovolemia,
hypomagnesemia
4 hyper: hyperglycemia,
hyperuricemia, hyperlipidemia (
thiazide causes hypercalcemia
while loop cause hypocalcemia)
49.Loop diuretics are
contraindicated in all of the
following except:
Renal diseases
Sensitivity to sulfonamides
Anuria despite using loop
diuretics
Na and water depletion
Ans: 1
50.Which of the following is true
about dry cough associated with
ACEI :
Mediated by bradykinin and
substance p
In women more than men
Develops within 6 months
Dose related
Ans: 4
51.Patient suffering from
arrhythmia and doctors are
discussing whether to prescribe
anti-arrhythmics or convert to
defibrillator
The following is true about anti-
arrhythmics:
The most common cause is
reentry and antiarrhythmics are
safer than operations, SA node
sets the pace for contraction of
the mycordium
The most common cause is
reentry and arrhythmia doesn’t
respond to Ca and Na channel
blockers
Antiarrhythmics are safer and SA
node sets the pace for
contraction of the myocardium
The most common cause for
arrhythmia is reentry, SA node
sets the pace for contraction of
the myocardium, arrhythmia
responds to Ca and Na channel
blockers
Ans: 4
52.Which of the following is true
of fluoxetine:
Used in bulimia nervosa, suffers
from extensive first pass
metabolism, its metabolite is as
potent as the parent drug, it has
t1/2 of 50 hrs
Make sure the choice u choose
includes all of the above
53.Patient having MI was
discharged, which agent is used
in prophylaxis from arrhythmia:
Quinidine
Verapamil
Sotalol
Lidocaine
Ans: 2
54.Case about patient has
glaucoma and is hypertensive,
which of the following is
avoided:
Fenoldopam
Nicardipine
Na nitroprusside
Labetalol
Ans: 1
55.Mechanism of action of
digoxin include all of the
following:
Positive inotropic effect
Decrease peripheral vascular
resistance
Has modulatory effect on
autonomic nervous system
Maintain ventricular rate in atrial
fibrillation
Ans: 2
56.Female patient has Which of the following side
dyslipidemia and lowered HDL, effects is associated with INH:
which of the following agents is Peripheral neuropathy
most suitable for her: ……
Fenofibrate ……
Niacin ……
Simvastatin Ans: 1
Colsevlem 61.Ipratropium bromide is
Ezetimibe approved for
Ans: 2 Maintenance of COPD
57.Conductivity in emulsion, the 62.In high therapeutic index:
dispersed phase for such The drug is less likely to cause
emulsion is: serious side effects
Aqueous 63.In HIV pt, CD4 bind to:
Non aqueous T-lymphocytes
Aqueous and non aqueous 64.In HIV pt, CD4 is less than:
Oily 200
Ans: 2 400
58.Conversion of emulsion 600
means: 700
Conversion of o/w to w/o and Ans: 1
vice versa 65.Which is contraindicated in
59.Particle size affects: prinzmetal angina:
Suspend ability Beta blockers
Penetrability 66.Doxazosin:
Dissolution rate Has first dose effect
Dose to dose uniformity 67.Drug used for mydriasis when
Uniformity of tablet checking for refractive errors :
All of the above Tropicamide
Ans: 6 Atropine
60.Patient diagnosed with TB, is Ans: 1
taking INH, rifampicin, 68.Toxicity of morphine can be
ethambutol reversed by:
Naltrexone In closed angle glaucoma
69.Ultra short acting barbiturate Standard one for open glaucoma
used for anesthesia : Ans: 4
Thiopental AUC questions
70.Dry gum emulsion: 74.Mec: minimum effective
The method is known as 4:2:1 concentration
Water and gum and oil are all 75.Mtc: maximum safe
triturated in a glass mortar concentration (if u find minimum
Water and gum are mixed and toxic concentration choose it)
then oil is added slowly 76.Area under mec : ineffective
None of the above 77.Are above mtc : toxicity
Ans: 1 78.Cmax: maximum plasma
I choose 1, others say its none of concentration
the above 79.Tmax: maximum time at
71.Which drug is not used in which plasma concentration is
parkinson’s disease: maximum
Chlorthalidone 80.If Cmax = 23.5 what is Tmax:
Bromocriptine 3 hrs
Amantadine 81.What is the concentration at
Rasagiline T= 12 hrs :
Ans: 1 5 ng
72.Timolol is CI in all of the 82.For how long does the drug
following except: remain in the body:
CHF 24 hrs
COPD 83.there were 5 calculation
Arrhythmia problems, they were simple all
HTN are solved by crisscross.
Ans: 4 84.What is the DOC in motion
73.Pilocarpine is used in all of sickness:
the following except: Scopolamine (hyoscine)
In narrow angle glaucoma 85.Which of the following is CI in
Alternatively with mydriatics to Parkinson:
separate the iris Haloperidol
86.What is the side effect of all 92.Anti-viral and for Parkinson:
antiarrhythmics: Amantadine
Torsades de pointe
87.What is the meaning of anti- 93.50% alchohol is to be diluted
glaucoma drug: with purified water, how many
Decrease intraocular pressure parts of purified water (0%
88.Dose of a drug is 0.2 mg, u alchohol) to prepare 20%
hve 15 mg, how many doses do preparation.?
u hve: 30parts water + 20 parts 50%
75 alchohol
Ans: 15/0.2= 75 Ans:
89.10 ml ampoule of 3% drug 50% alc
how many mls required to give …………………………………..20
150mg dose? 20%
3ml 0% pure
5ml water…………………………30
7ml
9ml 94.A dose for pt. is 75mg, how
Ans: 2 ml needed from 125mg/5ml
3 gm…..100ml solution:
0.15gm..? 5 ml
Take care of gm and mg 3 ml
90.Prinzmetal angina: 15 ml
Occurs at rest and is unrelated to Ans: 2
physical activity 125 mg…….5ml
Unresponsive to ccb and nitrates 75 mg……….?
Occurs at rest and is unrelated to 5*75= 375/125= 3 ml
physical activity, associated with 95.which is not true about
coronary artery spasm, occurs immune reconstitution
due to atherosclerosis inflammatory syndrome:
Ans: 3 Corticosteroids and anti-
91.Anti-HIV and for influenza: inflammatory drugs don’t
Amantadine shorten inflammation action
The action of antiviral start when
virus load is high
The pt start respond to
treatment when CD4 is high
Ans: 1
I am sorry that’s all I can
remember of the 100 questions,
the rest are 100% repeated
questions, all from the previous
years 2014,2015,2016
I wish u all good luck
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