Clinical Practice Guidelines for Management of

Hemorrhoids (ASCRS clinical guidelines)

GRADE strong recommendation, high GRADE weak recommendation, high quality
1A quality evidence, RCT without 2A evidence, RCT without important
important limitation limitation
GRADE strong recommendation, moderate GRADE weak recommendation, moderate
1B quality evidence, RCT with 2B quality evidence, RCT with
important limitation (inconsistent important limitation (inconsistent
result) result)
GRADE strong recommendation, low quality GRADE weak recommendation, low quality
1C evidence, RCT with important 2C evidence, RCT with important
limitation (inconsistent result) limitation (inconsistent result)

GRADE 1A, 1B, 1C: Benefit > Risk and Burden

GRADE 2A, 2B, 2C: Benefit = Risk and Burden