Anti-Psychotic

Other Heterocyclic Compounds

Olanzapine: Greater 5-HT2 than D2 receptor blocking actions (Atypical)
Risperidone: More equal D2 and 5-HT2 receptor blocking actions (“Atypical”)
Clozapine: Greater 5-HT2 than D2 receptor blocking actions (“Atypical”)
Quetiapine: Greater 5-HT2 than D2 receptor blocking actions (“Atypical”)
Aripiprazole: Partial dopamine agonists (“Atypical”)

Local Anesthetic Amides

Ropivacaine :
Lidocaine: Bind to inactivated sodium channels; decrease ERP
Bupivacaine
Levobupivacaine

Anti-Convulsants
Phenobarbital: Potentiates GABA activity
Pregabalin: Potentiates the release of GABA
Gabapentin: Potentiates the release of GABA

Skeletal Muscle Relaxant

Orphenadrine: Inhibits central muscarinic receptors
Eperisone

Opioid Analgesic
Fentanyl : Strong agonists at opioid receptors
Morphine : : Strong agonists at opioid receptors
Tramadol : Weak agonists at opioid receptors

Non-Opioid Analgesic
Paracetamol
Central Nervous System Stimulants
Status Epilepticus
Clonazepam: Potentiates GABA activity
Diazepam: Potentiates GABA activity

Generalized Tonic-Clonic Seizure (Grand-mal Seizure)

Zonisamide: Inhibits voltage-gated Na+ channels
Phenytoin: Inhibits voltage-gated Na+ channels
Topiramate: Inhibits voltage-gated Na+ channels
Lamotrigine: Inhibits voltage-gated Na+ channels
Oxcarbazepine: Inhibits voltage-gated Na+ channels
Carbamazepine: Inhibits voltage-gated Na+ channels

General/Partial Seizure
Perampanel

Selective serotonin reuptake inhibitor (SSRI)

Fluoxetine: Selective inhibitors of 5-HT reuptake at presynaptic neuron
Escitalopram: Selective inhibitors of 5-HT reuptake at presynaptic neuron
Sertraline: Selective inhibitors of 5-HT reuptake at presynaptic neuron
Vortioxetine

Mood Stabilizer
Lithium: Alters cation transport across the cell membrane and influences reuptake of
serotonin and/or norepinephrine; second messenger systems involving the
phosphatidylinositol cycle are inhibited; postsynaptic D2 receptor supersensitivity is
inhibited.

General Anesthetic
Propofol
Anxiolytic Benzodiazepine
Clorazepate: (Long-acting benzodiazipines)
Allosteric agonist of GABAA receptors that increase the frequency of chloride channel
opening

Benzodiazepine Sedative-Hypnotic
Midazolam: (Short-acting)
Allosteric agonist of GABAA receptors that increase the frequency of chloride channel
opening
Bromazepam
Alprazolam: (Intermediate-acting)
Allosteric agonist of GABAA receptors that increase the frequency of chloride channel
opening
Diazepam: (Long-acting)
Allosteric agonist of GABAA receptors that increase the frequency of chloride channel
opening

Sedative-Hypnotic

Diphenhydramine: Central H1 receptor blocker

Propranolol

Absence Seizure (Petit Mal)

Valproic Acid: Inhibits voltage-gated Na+ channels

Dissociative Anesthetic
Ketamine:

Anti-Psychotic Phenothiazine
Chlorpromazepine: Therapeutic effect due to blocking D2 and 5-HT2 receptors; many
adverse effects associated with blocking a adrenergic, muscarinic and histaminic receptors
Anti-Parkinsons
Carbidopa: Inhibition of peripheral dopa decarboxylase
Levodopa: Increases synaptic dopamine in brain
Biperiden:

Butyrophenones (Conventional)
Haloperidol: Strong D2 receptor blockers

Sedative-Hypnotic Benzodiazepines Amylase

Zolpidem: BZ1 benzodiazepine agonists

Mixed Opioid Agonist/Antagonist

Nalbuphine: Partial agonists at opioid receptors

Opioid Agonist
Loperamide: Weak agonists at opioid receptors

GABAb Agonist Skeletal Muscle Relaxant

Baclofen: g-Aminobutryic acid B (GABAB) agonist

Tricyclic Anti-Depressant
Clopramine: Therapeutic due to blocking NE and 5-HT reuptake at presynaptic neuron;
many adverse effects associated with blocking a-adrenergic, muscarinic and histaminic
receptors

Partial Mu Agonist (opioid)

Buprenorphine: Partial agonists at opioid receptors

Phenanthrene Opiate Derivative Agonist

Oxycodone: Moderate agonists at opioid receptors
GABA Derivative
Piracetam:

GABAergic Inhibitor Anti-Convulsant

Levetiracetam:

Partial Seizure
Lacosamide: