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Finite element based design of hip joint prosthesis

Thesis · July 2011


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FINITE ELEMENT BASED DESIGN OF HIP JOINT
PROSTHESIS

Thesis submitted in partial fulfillment of the requirements for the degree of

Master of Technology

In

Biomedical Engineering

By

Vicky Varghese
209bm1016

Department of Biotechnology & Medical Engineering

National Institute of Technology

Rourkela-769008, Orissa, India

2011
FINITE ELEMENT BASED DESIGN OF HIP JOINT
PROSTHESIS
Thesis submitted in partial fulfillment of the requirements for the degree of

Master of Technology
In

Biomedical Engineering

By

Vicky Varghese
209bm1016
Under the guidance of
Prof. Tarapada Roy

And

Prof. Kunal Pal

Department of Biotechnology & Medical Engineering

National Institute of Technology

Rourkela-769008, Orissa, India


ACKNOWLEDGMENTS

I wish to express my sincere gratitude to my thesis supervisor Prof. Tarapada Roy. For
his excellent guidance, encouragement and support during the course of my project work. He has
helped me gain knowledge in the field of mechanical engineering and also has taught me the
importance of simplicity and keeping a cool head during troubles and difficulties. His constant
talks of encouragement has always helped me to overcome the different hardships which I faced
during the project
I also express my heartfelt gratitude to my thesis co-supervisor Prof. Kunal Pal, for his
invaluable advice and guidance throughout the course of my research work. He is my role model
for sincerity, punctuality and discipline .I thank him for providing me a wonderful opportunity to
work on an interdisciplinary project.

I also would like to thank my friends Koteswarao and Shince V Joseph who have
helped my migration from Biomedical department to mechanical department a memorable
experience.

I also would like to thank my mallu gang member , my swimming team members, my lab
mates and my roommate Sadanand Jinna who were always a constant source of inspiration and
helped me during various ups and downs of the project

I would like to thank my parents who were always very much supportive for my project
and have helped me enjoy each and every success and failure during the project

Last but not the least I express my sincere thanks to the NESCAFE coffee shop girls
especially Rajitha and Sonia for providing a constant supply of coffee during good and bad
times in the project.
Table of Contents

List of Figures…………………………………………………………………………….………..I

List of Tables …………………………………………………………………….………….…II


Abstract……..……………………………………………………………….……….…………..III

1.Introduction……………………………………………….………………………………….…1

1.1 Objective of the Research ………………………….…………………………4

2. Literature Review…………………………………………………………………………........5

2.1 Biomaterials in Hip Joint Prosthesis……………………………….…………6

2.1.1 Metals ……………………………………………..……………….8

2.1.2 Ceramics…………………………………………………………….9

2.1.3 Polymer……………………………................................................10

2.1.4 Composites………………………………..………………….……11

2.1.4.1 Functionally Graded Composites……………………….11

2.1.4.2 Polymer-Ceramic Composites…………………..….…..11

2.1.4.3 Composites with biological macromolecules ………….12

2.2 Finite Element analysis…………………………………….….……13

3. Materials and Methods……………………………………………………………….……...23

4. Results and discussion…………………………………………………………………….. 27

5. Conclusion……………………………………………………………………….………….40

5.1 Future Work ………………………………………………..…….41

6. References …………………………………………………………………………………42
List Of Figures

1. Biomaterials used in Hip joint replacement.............................................................................4


2. 2-D model of the implant…………………………………………..…………………………24
3. Solid 92 Geometry …………………………………………………………………….……. 25
4. 3D model and the meshed model…………………………………………………………..….26
5. The models for the static and dynamic analysis with the forces
acting on them………………………………………………………………………..…..…..28
6. The static analysis of 316 L SS model, von mises stress,
displacement in x, y and z direction………………………………………………………….29
7. The static analysis of Ti-6Al-4V model, von mises stress,
displacement in x,y and z direction...................................................................................30
8. The static analysis of Co-Cr model, von mises stress,
displacement in x,y and z direction……………………………………………………...30
9. The static analysis of Magnesium alloy AZ 91,
von mises stress, displacement in x,y and z direction ……………………………..……31
10. The static analysis CF-PA 12 model, von mises stress,
displacement in x,y and z direction ……………………………………………..………31
11. The static analysis CF-PEEK model, von mises stress,
displacement in x,y and z direction………………………………………..…………….32
12. The static analysis bone model, von mises stress
displacement in x,y and z direction ………………………………………..……………32
13. The graph of the various forces acting on the hip joint prosthesis during one gait cycle….. 34
14. The variation of Von Mises stress during dynamic analysis by the metals and bone……… 35
15. The variation of Von Mises stress during dynamic analysis by the composite and bone….. 35
16. The variation of x-component of displacement during
dynamic analysis by the metals and bone ……………………………………………….36
17.The variation of x-component of displacement during
dynamic analysis by the composite and bone…………………………………………... 36
18. The variation of y-component of displacement during
dynamic analysis by the metals and bone ……………………………………………….37
19.The variation of y-component of displacement during
dynamic analysis by the composite and bone…………………………………………... 37
20. The variation of z-component of displacement during
dynamic analysis by the metals and bone ……………………………………………….38
21.The variation of z-component of displacement during
dynamic analysis by the composites and bone …………………………………………38

Page | I
List of Tables

1. Various Important Factors For The Selection Of Material For Biomedical Application….. 3

2: Mechanical Properties Of Alloys In Total Joint Replacement ……………………………. 9

3. Mechanical Properties Of Ceramics Used In THR …………………………………………10

4 .Mechanical Properties Of Composites ………………………………………..……………13

5. Material Properties Of Metals Used For The Implant……………………………………... 25

6. Material Properties Of Composites Used For The Implants ……………………………….26

7 .The Von Mises Stress And Yield Strength Of The Metals……………………………….. 33

8. The Von Mises Stress Developed In Composite Materials ………………………………..33

Page | II
Abstract

The work deals with the proper design of hip join prosthesis using finite element method.
Hip joint is one of the most important weight bearing and shock absorbing structure of the
human body. The longevity and functionality of the implant greatly depends on the design of the
implant. The shape of the implant is one of most easily recognizable feature in the design of the
implant. In the present study, Cobalt-chromium (Co-Cr), Low-carbon stainless steel of type
316(316L SS), titanium alloy (Ti6Al4V), magnesium alloy (AZ91), carbon fiber reinforced
PEEK (CF-PEEK) and carbon fiber reinforced PA -12 (CF-PA 12) have been used for implant
material which are biocompatible. ANSYS finite element package has been used for modeling
and analysis of the implant. The implant has been analyzed under static as well as dynamic
loading. Based on those analysis, some important results have been obtained and presented in the
results and discussion sections

Keywords: Hip joint, implant, finite element modeling, finite element analysis and dynamic
loading

Page | III
Chapter 1
Introduction

1|Page
1. Introduction
Hip joint is a diarthrosis or synovial joint between the femoral spherical head and the
convex-shaped acetabulum in the pelvis. It is wrapped in a capsule that contains a biological
lubricant, the synovial fluid (SF), which also acts as a shock-absorber (Nordin M 2001). The hip
joint can transmit high dynamic loads (7–8 times the body weight) and accommodate a wide
range of movements because of the presence of the SF and the ball-in-socket geometry. The hip
joint can be affected, more often in aged people, by chronic pain due to diseases such as
osteoarthritis, rheumatoid arthritis, bone tumors or traumas. In these cases, the best clinical
solution is the total hip arthroplasty, a surgical procedure that replaces the unhealthy hip joint
with an implant, preserving the synovial capsule. There are about 200,000 and 80,000
interventions/year are performed in the USA and in the UK, respectively, and they are estimated
to increase of about 170% by 2030 (O.K. Kurtz Steven 2007).

In orthopedic surgery, hip arthroplasty is considered as one of the greatest achievements


in the last decades, but from an engineering point-of-view hip implants need further
developments because they tend to have a limited service life of about 15 years, which is not
satisfactory for patients under 60 years of age (Brown 2006). In hip joint replacement operations,
the head of the femur is sectioned off, and the soft marrow is removed to create a hollow intra
medullar cavity through the centre of the femur shaft. An artificial implant (mainly comprising
of a long stem and a head) is then glued into the femoral cavity. The implant head fits into the
acetabular socket of the hip bone. The critical mechanical property requirements of the implant
material include (but are not limited to) high specific bending stiffness, high bending stiffness
comparable to that of the surrounding cortical bone, biocompatibility, corrosion resistance and
high endurance limit.

The region where two contacting surfaces have dissimilar mechanical properties, such as
implant–cement, bone–cement and implant–bone interfaces are the most susceptible regions to
failure in standard Total Hip Replacement (THR). The phenomenon of bone stress shielding can
be problematic at implant–bone interfaces because of the large difference in mechanical stiffness
between the metallic stem and the often osteoporotic and osteopenic host femur. Bone resorption
due to stress shielding and osteoporosis may cause micromotion. Micromotion along with
particle debris (formed during osteolysis) may cause implant loosening. This has motivated the

2|Page
development of hip stems from other materials which are more closely stiffness-matched with
the host femur.

The finite element method (FEM) is also referred as finite element Analysis (FEA) is a
computational technique used to obtain approximate solution of boundary value problems in
engineering(Hutton 2005). The advantage of Finite Element Analysis (FEA) for total hip
replacement studies is that the different implant configuration and design can be tested on
computer rather than by physical testing and eliminate and/or minimize the time and cost
involved for in vivo and in vitro experimentation The purpose of FEA in the field of orthopedic
biomechanics is to predict the mechanical behavior of bones, develop and improve the design of
implants.

Biomaterials used for total hip joint replacement (THR) have different wear rate and
liberate particle of different size which have different biological reactivity. The various factor
which are important for selection of materials for biomedical application are listed in the table 1
Table 1 various important factors for the selection of material for biomedical application
Factors Description
Biological Physical Mechanical
characteristics characteristics characteristics

1st level material Chemical Density Elastic modulus,


properties composition Poisson’s ratio, Yield
strength, Tensile strength
2nd level material Adhesion Surface topology Hardness, Shear module,
properties Shear strength, Flexural
modules, Flexural
strength
Specific functional Biofunctionality(non- Form ( solid, porous, Stiffness or rigidness,
requirements thrombogenic, Cell coating, film, powder Fracture toughness,
adhesion etc), etc), coefficient of fatigue strength, creep
Bioinert, thermal expansion, resistance, adhesion
Bioactive,Biostability, elastic conductivity, strength, impact
Biodegradability colour, refractive strength, proof stress,
index, opacity abrasion resistance
Processing and Reproducibility, quality, sterilizability, packaging, secondary
fabrication processability

3|Page
The different biomaterials which are used in hip joint prosthesis are as shown in the fig 1

Materials

Metal Ceramic Polymer Composite

Stainless steel Polymer-


Carbon
316L PMMA based
UHMWPE/
Alumina
HDPE
Cobalt- based Polysulfone
alloys Zirconia
PTFE Biomimetic
Calcium
phosphate
Titanium- based
materials Bioglasses

Fig 1): Biomaterials used in Hip joint replacement

In order to design a hip prosthesis adequately, the following important issues must be
considered: (1) stress shielding; (2) stem/bone interface stresses; and (3) prosthesis strength.

1.1 Objective of the Research


In this present study, three dimensional finite elements have been used for modeling and
analysis of the hip joint prosthesis. Six different types of materials have been considered for
prosthesis material in order to compare their performance under loading conditions. The implant
has been analyzed under static as well as dynamic loading.

4|Page
Chapter 2
Literature Review

5|Page
2. Literature Review

Some of the important work that has been carried out in this field are reported as below.
The section is divided into the different biomaterials which are used in hip joint prosthesis and
also about the different finite element analysis which has been done in the field of hip joint
prosthesis

2.1 Biomaterials in Hip joint Prosthesis

This section deals with the important works which have been carried out in the field of
biomaterials for hip joint prosthesis. Biomaterials used for total hip joint replacement (THR)
have different wear rate and liberate particle of different size which have different biological
reactivity.

(Bougherara, Zdero et al. 2011) did the biomechanical study of novel carbon fiber hip
implant and standard metallic hip implants. Carbon–fiber composite stems are able to reduce
stress gradients at the bone–stem interface and are biocompatible and its cross-weave surface
texture permits good bony on growth. CF/PA12 stems have a similar flexural modulus as human
cortical bone. It was found that the Composite was less mechanically stiff compared to metallic
stems, thereby yielding much lower stresses and much higher strains for the same applied load.
(H Bougherara 2010) to design a novel hybrid total knee replacement, it had improved stress
transfer to the bone in the distal femur. Carbon fiber-reinforced polyamide 12 lining layers were
used in place of the standard material. The new design has a higher stress transfer to the host
femoral bone compared to the standard TKR which helps in decreasing the stress shielding and
hence minimizes the consequence of bone loss and device loosening in the hybrid design. Only
static analysis was carried out for the FE analysis.

(I. Sridhar 2010 ) used carbon and aramid fiber reinforced polymer matrix(such as
polyether eher ketone-PEEK) composite material for hip joint prosthesis. The advantage of the
material is that they possesses superior biomechanical properties such as better fatigue strength,
chemical resistance, environmental stability and resistance to sterilization by ϒ radiation and the
stiffness of the implant can be tailored according to the requirement. The optimal ply winding
sequence of femoral stem to obtain orthotropic moduli similar to that of natural bone is achieved

6|Page
using a MATLABR. Stress analysis was carried out using ABAQUS/CAE commercial finite
element analysis software. The optimal ply sequence was found to be [-7515
/6015/4515/3015/6515]5 . CF/PEEK produced similar Von Mises Stress patterns as those of the
intact femur, while metallic stem experienced high stress at bone stem interface while the
surrounding bones experienced lower stress which produces stress shielding which causes bone
resorption. (Rahaman, Huang et al. 2010) did the in vivo studies on the use of a composite of
Al2O3 and niobium (Nb) for potential use as an alternative femoral head material. The composite
is fabricated by hot pressing. The flexural strength of Al2O3–Nb laminates in four-point loading
was 720 ± 40 MPa, compared with a value of 460 ± 110 MPa for Al2O3. The interfacial shear
strength between Al2O3 and Nb, measured by a double-notched specimen test, was
290 ± 15 MPa. The composite femoral head combined the low wear of an Al2O3 articulating
surface with the safety of a ductile metal femoral head which could reduce the risk of
catastrophic brittle failure of Al2O3 femoral heads in vivo.

(Cilingir 2010) found that ceramics are a good alternative to metal because of its better
wear resistance for bearing couple material. Contact pressure distribution was significantly
affected by a reduction in radial clearance. The major concern regarding the use of ceramic is the
stress shielding compared with metallic resurfacing prosthesis. The best design for ceramic
resurfacing prosthesis was to have a alumina implant with a metal backing. (Kane, Yue et al.
2010) investigated the effects of zirconia fiber reinforcement on the fatigue life of acrylic bone
cements. PMMA cement with sintered straight or variable diameter fibers (VDFs) was added to
test the reversed uniaxial fatigue until failure. The cement reinforced with 15 and 20 vol%
straight zirconia fibers had the mean fatigue life increased by 40-fold, on average, compared to
a commercial benchmark (Osteobond™). The a cement reinforced with 10 vol% VDFs had a
higher mean fatigue life the same cement reinforced with 10 vol% straight fibers.

(Fujihara, Huang et al. 2004) for orthopedic bone plate application studied the fabrication
and characterization of carbon/PEEK fabric composite. It was found that the unidirectional
laminated composites suffer the delamination fracture. The micro-braiding technique contains
matrix and reinforcement fibers and can be fixed into the complicated contour of orthopedic
fixations. It was found that the composite had a 55-59 % better bending stiffness, 40-63 % yield
bending moment and 54-77 % maximum bending moment. (Staiger, Pietak et al. 2006)

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magnesium-based implants have the potential to serve as osteoconductive, biocompatible, and
degradable implants for load-bearing applications because it is a lightweight metal with
mechanical properties similar to natural bone. The elastic modulus and compressive yield
strength are closer to those of natural bone than the other commonly used metallic implants. It is
naturally found in bone tissue and is essential to human metabolism. For orthopedic applications,
alkali-heat treatments, is used to induce a biomimetic precipitation of calcium phosphate at the
implant surface.The different biomaterials which are used in hip joint prosthesis are described as
below

2.1.1Metals
Metals have been the primary material used for THR due to superior mechanical
properties. Originally steel was used to make femoral component of hip joint that was replaced
by cobalt-chromium-molybdenum alloy (VitalliumTM). Most commonly, for femoral part
stainless steel, Co–Cr alloys, or Ti alloys are the metals of choice and for the cup component
alumina or zirconia ceramic, polytertrafluoroethylene (PTFE) or Co–Cr alloy are usually used
(Joa˜o F.Mano 2004). However there are many nuisance associated with metals like release of
dangerous particles from wear debris, detrimental effect on the bone remodelling process due to
stress shielding and also loosening of the implant tissue interface. Metals like Cr and Ni used
some cases are reported to cause oxidative damage to cell signaling molecules and also induce
osteolysis (Sargeant and Goswami 2007). It has been shown that the degree of stress shielding is
directly related to the difference in stiffness of bone and implant material (Huiskes and Chao
1983; Black 1987). Titanium alloys are favorable materials for orthopedic implants due to their
good mechanical properties. However, titanium does not bond directly to bone resulting in
loosening of the implant. Undesirable movements at the implant-tissue interface results in failure
cracks of the implant. The application of bioactive coatings to titanium-based alloys enhance the
adhesion of Ti-based implants to the existing bone, resulting in significantly better implant
lifetimes than can be achieved with materials in use today.
An ideal bioactive coating would bond tightly both to the bone and the metal. Some
ceramic coatings are known to be bioactive and have been tested on Ti implants. Since the
modulus of the Ti alloys is lower than that of the Co–Cr–Mo alloys, they have been more for
THR components. The elastic modules of the Ti alloys have been engineered to be more suitable

8|Page
by heat treatments resulting in microstructures that have a reduced elastic modulus. Metallic
femoral head articulating inside a polymeric (PTFE or UHMWPE) acetabular cup has been one
of the most favorable THR element structure (Wang, Liu et al. 2009). Clinical results show that
excessive wear and wear debris is the primary cause of failure of UHMWPE or metal implants.
Thus, the use of materials with lower modulus and strength such as polymers appear to be more
useful for use as bone biomaterials
Table 2 : Mechanical properties of alloys in total joint replacement (Katti 2004)
Alloy Microstructure Tensile strength( MPa) Modulus ( GPa)
Cp Ti (pure titanium) {α} 785 105
Ti–Zr Cast {α’/β} 900
Co–Cr alloys 655–1896 210–253
Co–Cr–Mo {Austenite (fcc) + 600–1795 200–230
hcp}
Ti–6Al–4V {α ‘/β} 960–970 110

Ti–6Al–7Nb {α’/β} 1024 105


Ti–12Mo–6Zr–2Fe {Metastable β} 1060–1100 74-85
Stainless steel 316 L {Austenite} 465–950 200
Ti–35Nb–5Ta–7Zr {Metastable β} 590 55
(TNZT)

2.1.2. Ceramic
Ceramics are most compatible bone substitute biomaterials used for joint and joint
surface replacement. Since 1970s, when ceramic was introduced, ceramic components are being
used for total hip arthroplasty (THA). Compared with metallic components, ceramic femoral
heads for THA have the potential advantage of lower wear rates in articulations with acetabular
liners. Alumina due to their excellent biocompatibility, stability in physiological environment
and high strength are used frequently in THA. Conventional ceramics such as alumina were
evaluated due to their excellent properties of high strength, good biocompatibility and stability in
physiological environments (Cao and Hench 1996) However, alumina materials have poor
chemical bonding with tissues, as a result use of it as a potential bone substituent is limited.
Other biocompatible ceramics like Zirconia, yttria, Bioglass, C-( Graphite) and Calcium
phosphate ceramics like HAP (Ca10(PO4)6(OH)2 ) and Tricalcium phosphate (TCP) (Ca3(PO4)2)

9|Page
are widely used for hard tissue replacement because of their osteoconductive properties (J.D.
Helmer 1969; L.L. Hench 1993; Katti 2004).Alumina and Zirconia are primarily used in the
fabrication of femoral heads. For hip replacement metallic femoral stem is used in conjugation
with alumina femoral and an acetabular cup made from UHMWPE for the opposing articulating
surface.
As compared to conjugation of metal with UHMWPE, the wear rates for alumina on
UHMWPE conjugation is reported to be 20 times less than that of metal- UHMWPE
conjugation. Ceramic components are used increasingly in total hip arthroplasty (THA).
However, the use of ceramic components is also associated with unique risks, including sudden
fracture and intolerable bearing noise or squeaking. Alumina and titanium dioxide have been
used as nano ceramics separately or in nano composites with polymers such as polylactic acid or
polymethlyl methacrylate. The nano ceramic formulations promote selectively enhanced
functions of osteoblasts (bone-forming cells. Ceramic particles are also weakly genotoxic and
non-cytotoxic on human fibroblasts in contrast to Co Cr particles, which show dose-dependent
cytotoxicity and genotoxicity (Tsaousi, Jones et al. 2010)
Table 3 Mechanical properties of ceramics used in THR (F.O. Schmitt 1988; S. Ramakrishna
2001)
Ceramic UCS (MPa) UTS ( MPa) Modulus ( GPa)
Zirconia 2000 820 220
Alumina 4000 300 380
Bioglass 1000 75
C –( graphite) 138 25
C-( Vitreous) 172 31
HAP 600 50 117
C- ( LTI pyrolitic) 900 28
AW glass- Ceramic 1080 118

2.1.3 Polymers
Polymers of very high stiffness and strength are used for orthopaedic surgery. For
orthopedic applications, common polymers used are: acrylic, nylon, silicone, polyurethane, ultra
high molecular weight polyethylene (UHMWPE), and polypropylene (PP). Highly stable
polymeric systems such as PTFE, UHMWPE or poly(etheretherketone) (PEEK) have been
investigated due to their excellent mechanical properties. Polyethylene wear particles are

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reported to enhance osteolysis. Methacryloyloxyethyl phosphorylcholine (MPC) over metal
surface provides high lubricity and also reduce wear (Kyomoto, Iwasaki et al. 2007).
Biodegradable polymers both natural and synthetic like poly(dioxanone)(PDO),
poly(trimethylene carbonate) (PTC) copolymers. PLA and PGA, polycaprolactone (PCL),
polyanhydrides (PA), polyorthoesters are being subjected to THR research (T.H. Barrows 1986)
A shift from biostable to biodegradable biomaterials for mediacl application is seen in recent
time and biodegradable polymers have extensive application in tissue engineering. Due to
versatility polymeric material have replace other class of biomaterial and also used in
combination with metal and ceramic (Nair and Laurencin 2007)

2.1.4. Composites:

2.1.4.1 Functionally graded composites

The graded composition of functionally graded composites marks them with two different
properties at two ends of the composites. Ceramic- metals composites are prepared by powder
metallurgy methods, ceramic part provides biocompatibility and metals part marks a good
mechanical property to the composite graft e.g. HAP/titanium composites (F. Watari 1997),
fluoroapatite/ TCP (H. Wong 2002), HAP/Zirconia composites.

2.1.4.2 Polymer-ceramic composites


Ceramic and polymer combination biomaterial have superior mechanical properties and
biocompatibility with tissues and are better than solitary polymer or ceramic used for THR(N.
Galego 2000) . Polymers has very low module as compare to bone, high weight % of filler
component is used. HAP has been the material of choice for ceramic filler component and high
% of HAP is been used with polymers of low module eg. PLA [poly(lactic acid) ], PHA [poly(_-
hydroxyalkanoates)] . Composites of (PHA) with HAP have shown ultimate strength, elastic
modulus and elongation at break similar to bone and are being investigated as potential materials
for THR(N. Galego 2000). Biodegradable polymers ( starch- based) and ethylene vinyl alcohol
(EVOH) filled with 10-30% HAP has shown high module (about 7GPa) (44) has prospective
for THR.

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Coupling agents like zirconate, titanate and silanes have been used for EVOH- HAP,
HAP-Ca and PLA-HAP combination composites (Y.E. Greish 2001; T. Kasuga and . 2003).
However, composites have poor adhesive properties and bone repairing materials like bioglass
and bioceramics are used to enhance adhesion to tissues. HAP along with bioceramics and
bioglasses have been studied extensively as bone repairing material and is used as a coating for
implanted prostheses to enhance direct adhesion to bone tissue (A. Ravaglioli 1992). Apart from
that number of polymer ceramic composites are used that are shown in table4 with their
mechanical properties as compare to bone

2.1.4.3 Composites with biological macromolecules

Bone is a nanocomposite of HAP and type I collagen. Composites like HAP in


combination with soluble collagen, gelatine, polyacryl acid, phosphoprotein, bone Gla protein
etc is used to mimic bone structure (M. Kikuchi 1999; M.C. Chang 2001; S.C. Liou 2003) HAP–
gelatin composites are being currently studied for potential bone replacement materials (S.C.
Liou 2003). Other biomimetic routes include in situ mineralization of HAP in the presence of
polymeric macromolecules such as calcium binding polyacrylic acids of high molecular weight
(K.S. Katti 2001). Molecular level association of polymers with HAP represents a significant
mechanical properties exhibits a core-shell configuration(S.C. Liou 2003) . Composites of HAP
with bone phosphoprotein, bone Gla protein and collagen (Heywood et al., 1990) have also been
attempted. Mechanical properties in the above composite systems are still inadequate for the
potential use of these composites for total bone replacement. The biomimetic composite
obtained has excellent biocompatibility and biointegrative activities, equivalent to autogenous
bone and are much better than other artificial bone materials (M. Kikuchi 1999). Hydroxyapatite
and collagen composites (HAP/Col) have the potential in mimicking and replacing skeletal
bones. The combination of HAP with natural cell cytoskeleton proteins has been studied
extensively as a favorable composite for bone tissue engineering due to their natural biological
resemblance and properties (Alina Sionkowska 2010).

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Table 4 Mechanical properties of composites

Materials UTS (MPa) Elastic modulus Elongation at References


( GPa) Break ( %)
Functionally graded: Bending 100–160 (X. Wang 2002)
HAP/Yttria, 0–40% strength:
yttria 160–200
content w/w
PHB/HAP, 30% w/w 67 2.52 2.65 (N. Galego 2000)
P(βHB-co-8–24% 62–23 2.75–0.47 2.25–5.42 (N. Galego 2000)
βHV)/HAP, 30%w/w
Chemically coupled 18.34–20.67 0.88–4.29 >500 to 2.6 (Wang, Liu et al.
HAP/PE, 7–40 vol% 2009)
filler
Nano HAP, 30–70 to 35.8–78.4 (Bending) 2.3–6.2 Elongation 1– (X. Wang 2002)
60 w/w 2.8
PAAC/in situ nano 20–60 1–1.8 2–6 (K. Kato 1997)
HAP, 40–70 w/w
Starch-EVOH (SEVA) 42.3–30.2 1.8–7.0 14.7–0.6% (M.C. Chang
blend/HAP, 10–30% strain 2001)
w/w
Starch-EVOH (SEVA) 43.3–49.9 3.75–4.3 1.33–1.99 (M.C. Chang
/10% HAP w/w with 2001)
1% coupling agents
(zirconate, titanate and
silane)

2.2 Finite element analysis

According to the study conducted by (S.A. Asgari 2004) the finite element analysis was
conducted using 10 noded tetrahedral element. Two types of materials, bone and implant were
assigned to the models. Von Mises Stresses were calculated for intact bone, stem less and
stemmed structure. Intact bone was considered as control solution for evaluation of two
structures. From the analysis it was found that the stem less implant was a perfect fit to the
values of strain, but there were certain problems associated with the stem less implants. The
femoral neck region of the model had a sudden change in the stress value which might become a

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source of problem post-operatively and might fail. The sub-trochanteria area also produced high
stress concentration at the lateral side which might result in implant displacement or in bone
atrophy and consequently bone loss in that area. (Mattei, Di Puccio et al. 2011) describes the
main lubrication and wear models of hip implants. Lubrication and wear models have been used
to investigate the effect of geometric and material parameters on the lubrication regime and on
wear trends, One of the most significant findings that comes out from this study is that, although
lubrication and wear are two different aspects of the same tribological scenario, they are modeled
completely neglecting each other. Lubrication models do not consider the 3D topography of the
articulating surfaces as well as the asperity contact and surface evolution caused by mixed and
boundary regimes; on the other hand wear models simulate only dry contact. These limitations
underline the difficulty of a realistic theoretical description of the hip implant tribological
behavior, increased by the complex model solution, which need to cross use several numerical
approaches.

In a work by (Habiba Bougherara 2010) the FE analysis of two piece modular and single
piece mono block revision hip implants. Analysis was carried out using hip implant alone and
hip implant implanted in the femur model. From the analysis it was found that there was a
significant amount of stress absorption by the modular implant than in mono block, which
suggested that the host femur carried more of the load when the mono block device was
employed. A stress concentration on the modular implant occurred at the modular junction which
may be susceptible to failure, however no comparable potential failure points were identified on
the mono block prosthesis.(S. Gross 2001) studied the use of a hollow stemmed hip implant for
reducing the effect of stress shielding. Finite element analysis was used to compare the stresses
produced in the various regions of hip implants. The parallel and tapered hollow stems produced
an increase in both proximal bone and cement stresses relative to the solid stem. The results
showed that the reduced proximal stress shielding can be obtained with stems with hollow
sections compared with solid stems. The advantage of hollow stem lies in the greater
controllability of rigidity while maintaining an acceptable anatomical fit. The outer shape of the
stem can be chosen according to the anatomical criteria and the inner dimensions then adjusted
to optimize bone stresses.

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(Chaodi Li 2002) used numerical method to predict the progressive failure of a thick
laminated composite femoral component for total hip arthroplasty. Using the CT scan data and I-
DEAS software the 3-D model of the femur was created. Carbon fiber reinforced
polyetheretheketone(C/PEEK) laminated composite was used to fabricate the prosthesis. The
model was meshed using high order 20 noded quadratic brick elements and 15 node wedge
elements (element types C3D20 and C3D15 in FE software ABAQUS). The critical region
limiting fatigue life was identified, using SED to occur in the neck region of the implant. The ply
orientation and the stacking sequence has a great significance in the stress distribution (David
Bennett 2008) performed the finite element analysis (FEA) of six hip stem design. Forces
ranging from 2.5-7 kN was applied. The cross-section which comprised of a circle in the medial
end and a square at the lateral end was found to provide suitable design characteristics.
Assuming that the implant was made of metal and polyethylene liner the fatigue and wear
analyses were performed. CoCrMo, Ti and SS and bone cement was used for the analysis. From
the fatigue life studies it was found that Co Cr Mo did not fail under wear conditions until around
20 years, while the SS and Ti64 failed in 11 years

(Anthony L. Sabatini 2008) conducted the finite element analysis for stems with various
cross sections. Von Mises stress and displacement was recorded at designated locations. Co-Cr-
Mo, stainless steel SS 316L and titanium alloy Ti-6Al-4V was used to perform the analysis. Ti-
6Al-4V exhibited lower stress compared to other two materials. Stem cross section of trapezoid,
oval, circular and elliptical were tested for stress distribution. Even distribution of stress was
found in elliptical and circular cross section.(Oguz Kayabasi 2006) conducted the FE analysis of
four stem shape to design and optimum stem shape. Using the average body weight the static
analysis was conducted and dynamic analysis was conducted using a load of walking condition.
The stem with a notched geometry produced a better fatigue resistant structure. Ti-6Al-4V was
found to be more stable in the analysis

(Oguz Kayabasi 2007) conducted the parametric modeling of the newly designed hip
implant under body weight load condition. Ti-6Al-4V and cobalt-chromium was used as the
material for the hip implant. The stem shape was optimized by numerical shape optimization
method. Implicit static analysis was conducted with ANSYS software for femur-bone cement
interface, and the bone-cement-implant interface. Bone cement was considered to be a

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viscoelastic material model. The model consisted of 72,458 elements: 48,205 for the femur,
13,760 for the bone cement and 10,493 for the implant. These were modeled with SOLID45 of
ANSYS element library, defined by four nodes each having three degrees of freedom. Fatigue
calculations were carried out for both the materials using Goodman, Soderberg, and Gerber
fatigue theories and it was found that the best stem shape for fatigue under static and dynamic
loading condition was fabricated of Ti-6Al-4V. (Santanu Majumdera 2007) simulated the
sideways fall which is the main cause for hip fracture in elders. Finite element model of the
pelvis-femur complex was developed using the computed tomography scan. MIMICS was used
to produce the solid model after proper thresholding and segmentation. The output was taken in
DXF format and was transferred to IGS format with the help of Mechanical Desktop (version
6.0, Auto Desk Inc.) with the help of ANSYS-LS-DYNA software the IGS data was translated
and three dimensional (3D) FE model of human pelvis-femur-soft tissue complex was generated
and analyzed for various side way falls and accident like conditions

(Mohammed Rafiq Abdul-Kadir 2008) did a finite element model of the construct to
predict micro motion and instability of femoral stem. The model was correlated with an in vitro
micromotion experiment carried out on four cadaver femurs. Using AMIRA software (Mercury
Computer Systems, Inc., San Diegao, CA) the 3D model of the hip was constructed. Using
Marc.Mentat (MSC.Software, Santa Ana, CA) software the computer model was converted to
solid linear tetrahedral element. In this study Marc finite element software package was used.
The model was loaded with 3kN at the shoulder of the stem to match the experiment condition.
From the study it was found that for achieving good primary fixation and stability of the implant
an optimal level of interference fit to be around 50µm.To predict the wear appearing in hip joint
(James Shih-Shyn Wu 2003) proposed a computer algorithm using FE analysis based on
Archard’s wear law , contact features and analogue wear process. The femoral head was made of
stainless steel with an outer diameter of 22mm and the surface roughness was between 0.004 and
0.005µm. The acetabular cup was made of UHMWPE with an interior diameter of 50mm. The
wear coefficient of 0.8x10-6 mm3/Nm was taken between hip joint and acetabular cup.
Hexahedron brick element was used to mesh the femoral head and the acetabular cup.
FORTRAN with 64-but data precision was used to run the program. From the analysis it was
found that for a femoral head with a radius of 22 mm had the average yearly wear depth of 0.111

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(mm per year ) and the average wear volume is 42 (mm3 per year) which matched with the
clinical measurement and experiment data.

(A. Zafer Senalp 2007) did the finite element analysis of four different stem shape of
varying curvature. Using ANSYS finite element codes the static, dynamic and the fatigue
behavior of the design was analyses. For CAD modeling the stem shape Pro /Engineer was used.
ANSYS Workbench software was used for studying the fatigue behavior of the stem shapes. Ti-
6Al-4V and cobalt-chromium metal materials were used for the stem design and the results were
compared with the commonly used Charnley model. The model was meshed using SOLID187
which has a quadratic displacement and is well suited to modeling irregular meshes. The element
is defined by 10 nodes having three degrees of freedom at each node. From the analysis it was
found that Ti-6Al-4V had the better stability under static and dynamic loading conditions and the
stem with notched geometry was the best design for both static and dynamic loading conditions.
(E. Pyburn 2004) used different femoral cross section geometries in the presence of bone cement
for finite element analysis. It was found that the more force is transferred through the implant
with stiffer implant material. It was found that linear recesses and broad lateral areas help
transfer more of the load in a compressive manner and reduce implant failure

(Achour, Tabeti et al. 2010) used Abaqus 6.5-1 code to model the femoral part. Crack tip
was meshed using focused mesh. The plastic and cement layer was defined as isotropic and
linearly elastic and bone material was defined as orthotropic and elastic. It was found that
opening and shearing propagates the interfacial crack (cement/bone). In the distal zone the
cement/implant crack propagates by shearing.

(Dopico-González, New et al. 2010) used probabilistic finite element analysis to study
the effect of implant geometry and femoral characteristics on uncemented hip implant. Mimics
was used to generate the geometries of the model. 4- noded tetrahedral element was used to
generate the mesh and ANSYS 11.0 was used for the analysis. From the study it was found that
the maximum nodal micromotion for the IPS implant was less than 30 μm which helps in
osseointegration to take place.(Anderson, Ellis et al. 2010) analyzed the finite element models of
hips with rigid bone material assumption and simplified geometry. The bone-cartilage geometry
was subject specific, spherical and rotational conchoids. It was found that the subject-specific
bone geometry with smoothed articulating cartilage predicted evenly distributed patterns of

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contact and underestimated pressures. Higher pressures were obtained in models with rigid bones
than the subject-specific model with deformable bones.

(Jhurani and Fred Higgs Iii 2010) did the finite element analysis of artificial hip joint
made of metallic femoral head and ultra-high molecular weight polyethylene (UHMPE)
acetabular cup. The wear particle which is generated in the joint was simulated within the
lubrication regime. Mathematica programming environment was used to develop the code. The
femoral head with acetabular cup for a constant load support by the joint was used for the first
part of the code and the second part of the code was developed to simulate the motion of the
wear particles within the synovial fluid. It was found that less than 20% of the particles actually
collide with the femoral head or cup. (Bouziane, Bachir Bouiadjra et al. 2010) studied the micro
cavities in the cement mantle of total hip arthroplasty using the three dimensional finite element
method. It was found from the results that the higher stress was obtained at the micro cavity
present at the proximal zone of the prosthesis. When the micro cavity was present at the
proximal or the distal end the static loading generated higher stress than the dynamic loading and
when the microcavity was present at the medial zone then the dynamic loading generated higher
amount of stress than the static loading. (Jun and Choi 2010) developed a software system to
design a patient specific hip implant. To construct the hip implant the parameters which are
required are anatomical femoral axis, femoral shaft isthmus, femoral head center/radius, neck
shaft angle, femoral neck, anteversion, head offset length, and canal flare index (CFI). The
program was developed in C++

(Pal, Gupta et al. 2010) studied the load transfer and failure mechanisms of short-stem
femoral resurfacing component. In this study the stem length was reduced by approximately 50%
as compared to the current long-stem design. The loading conditions were normal walking and
stair climbing. Shortening the stem length helped in better physiological stress distribution and
better bone apposition, and reduced strain concentration in the cancellous bone around the
femoral neck–component junction and the bone resorption was considerably less .The short-stem
design offers better prospects than the long-stem resurfacing component.(Yang, Zhang et al.
2010) studied the loosening of model cemented joint replacement under cyclic loading condition
and the fatigue strength of the bone/cement interface was characterized. Using Digital Image
Correlation the loosening of the bone/cement interface was quantified and the specimens were

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subjected to cyclic shear of 10 million cycles. It was found that with the increase in surface
roughness of the bone and the degree of cement inter digitation the fatigue strength increased.

(Rothstock, Uhlenbrock et al. 2010) developed the elastic and plastic finite element (FE)
models of the proximal femur to study the influence of interference, bone quality and friction on
the micromotion during walking and stair-climbing. It was found that at an interference of 30 μm
the plastic deformation starts and at 150 μm interference the amount of plastified bone at the
interface increases up to 90%. It was found that for a stable situation a 60 μm press-fit and a
force of 4 kN allowed bony ingrowth for both constitutive laws (elastic, plastic) for walking and
stair climbing.(Waanders, Janssen et al. 2010) investigated how the mechanical response of the
cement–bone interface at various load levels in terms of plastic displacement and crack
formation. The deformation modes of the cement were ‘only creep’, ‘only damage’ or ‘creep and
damage’. It was found that the fatigue cracks which arose at the contact interface and
subsequently progressed further into the bulk cement was the major time dependent plastic
displacement found at the cement–bone interface. It was found that the increase in stresses in the
bone at the interface was due to the fatigue cracking of the cement, while cement creep did not
appear to have a considerable effect on bone stresses

(Meireles, Completo et al. 2010) quantified the strain shielding effect on the distal femur
after patellofemoral arthroplasty because it leads to a reduction of density in bone surrounding
the implant. Strain shielding is a mechanical effect occurring in structures combining stiff with
more flexible material. The studies were carried out at three activities of daily living: level
walking, stair climbing and deep bending at different angles of knee flexion. It was found that
with the increase in angle of knee flexion and applied load the occurrence of strain shielding was
more significant.

(Bah, Nair et al. 2009) used a mesh morphing technique to automate the model
generation process. From slices obtained from CT scan data the femur geometry was generated.
First a set of points describing the femur in 3D space, appropriate for CAD analysis, was created
and the outline curves were exported into I-DEAS to form a 3D volume and then imported into
ANSYS 11 ICEM CFD for the analysis. The bone interface region was meshed with 53,743
nodes and 232,404 elements. The rest of the femur was made of 80,522 nodes and 398,605
elements and the implant had 17,937 nodes and 78,482 elements. (Helgason, Pálsson et al. 2009)

19 | P a g e
studied the risk of failure of femoral prosthesis with direct skeletal attachment using finite
element analysis. Hollow cylindrical shaft was used to model the femur and the implant was
assumed to have a hollow conical shape. The average inner and outer diameter of the femoral
shaft were estimated from the CT data using a threshold of HU = 200 and the outer and inner
radii were found to be R = 16 mm and r = 8 mm, respectively. Meshing was done using 10 noded
tetrahedral solid element. It was found that the implant system had three times greater chance of
failure than the intact femur and it was also concluded that the porous coated implant can be
beneficial for Osseo integrated fixation than the normal implant.

(Dopico-González, New et al. 2009) used probabilistic methods to control the behavior
of the implanted femur to determine the performance of the construct. Meshes for both bone and
implant were generated using 10 noded tetrahedral elements in ANSYS and the material property
was assumed to be elastic, linear and isotropic and the bone was considered homogeneous. The
parameters that were considered for the probabilistic modeling are the magnitude of the applied
load (P) and the angle between the load and the z-axis (ANGZ), the Young's modulus of the
bone (EXB) and the Young's modulus of the prosthesis (EXP). Monte Carlo simulation
techniques were applied to provide simulations. From the study it was found that the parameters
that most affect the value of the maximum strain are the bone stiffness, followed by the load and
the prosthesis stiffness.(Afsharpoya, Barton et al. 2009) investigated the Charnley and C-Stem
model for the fixation failure and loosening in cemented total hip prosthesis. Strain developed on
the femoral surface was compared in 3 D finite element model and in an in vitro experimental
simulation. It was found that proximal de bonding of the cement/bone interface and distal de
bonding of the implant/cement interface combined with the heel-strike position applies a high
retroversion torque to the femoral stem which increases the strain transfer to the cement that may
ultimately lead to the breakdown of the cement mantle leading on to osteolysis and loosening of
the prostheses.

(Yang, Wei et al. 2009) developed a hip prosthesis model using FEM studies on the
already available prosthesis with certain amount of modification the prosthesis was made with a
hollow stem and the bore depth is extended to the distal end of the stem. Since the proximal stem
has a larger cross-sectional area and higher rigidity the wall thickness is 3 mm below a depth of
80 mm, and gradually becomes 2 mm in the upward direction. In the lower part of the proximal

20 | P a g e
stem region, the cross-sectional area is smaller because of high stress-critical region. The cross-
sectional area was larger at higher part of proximal stem region because of the stress-safe region.
The maximum stress of this final hollow design stem was 371.2 MPa (von Mises stress) and
383.5 MPa (maximum tensile stress).(Mathias, Leahy et al. 1998) studied the finite element
analysis on a hip prosthesis with two holes in the shoulders which are used to engage stem
introducer. From the FE analysis it was found that there was no unacceptable stress level around
the holes. All the three prosthesis satisfied the cyclic mechanical testing of 5 million loading
cycles at a peak load of 2.3kN with no evidence of damage.

(Gross and Abel 2001) to reduce the effect of stress shielding, a study on the use of
hollowed stemmed hip implant was done. The stresses at the proximal femur were calculated for
hollowed stem and solid stem with different values of elastic modulus. Stress shielding was
reduced in hollow stem. It was found that there in all tapered stem there was an increase in
proximal stress in the bone (El'Sheikh, MacDonald et al. 2003) used finite element analysis to
optimize the material and design for hip joint prosthesis. The loading condition in static analysis
on the head of the femur was taken as 8.7 times the body weight (BW=70 kg) while stumbling
which is resolved into Fx=2188.86N, Fy=-669.56N and Fz=5472.1N. It was found that along the
medial and lateral side of the hip prosthesis the axial stress was higher in dynamic loading than
in static loading. At the distal direction the curves diverges. From the studies it was concluded
that dynamic load condition analysis is required to get a close to reality results

(El-Sheikh, MacDonald et al. 2002) used the finite element analysis for studying the
physiological loading condition on hip joint prosthesis. The fatigue strength was used as the
selection criteria for material. The meshing of the cancellous bone was done using 4- noded
isoparametric tetrahedral elements and 8 noded isoparametric brick element was used to mesh
the rest of the model. It was found that the higher prosthesis stress and lower cement stress is
caused due to increasing prosthesis stiffness. At the proximal region maximum cement stresses
occur which may cause cracks to propagate in the distal direction.(Kluess, Martin et al. 2007)
studied the dislocation of the hip replacement based on the head size. Experimental and
numerical studies were carried out on cobalt chromium heads with head diameter of 28,32,36
and 40 mm with four different ultra-high molecular weight (UHMW) polyethylene liners, each
liner was 7 mm thick and the 2mm of head inset of acetabular component was used. ABAWUS

21 | P a g e
V 6.4 was used for the finite element modeling. It was found that there was a decrease in contact
stresses with the increase in femoral head size.

(Bouiadjra, Belarbi et al. 2007) computed the stress intensity factor along the crack front
to analyze the fracture behavior of cement of reconstructed acetabulum. It was found that the
sliding and tearing effect of the crack located at the free edge of the cement mantle was less
risky than the crack propagation by opening effect. When the crack is inclined at 45º the sliding
effect is more dominant (Li, Granger et al. 2002) developed the 3 D FE model of the femur using
I-DEAS. The prosthesis was fabricated using a carbon fiber-reinforced polyetherehterketone
(C/PEEK). The meshing was done using 20 noded quadratic brick elements and 15 noded wedge
element. The finite element modeling of the femur/implant was done using FE modeling package
I-DEAS. Form the analysis it was found that the fatigue life was limited due to the critical region
present at the neck of the implant.

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Chapter 3

Material and Method

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3. Materials and Methods
The two dimensional (2-D) model of the hip implant is shown in Fig 3 was created using
CAD software AUTODESK MECHANICAL 2008. The dimensions required for the
construction of the model was obtained from the literature (Oguz Kayabasi 2006). To reduce the
stress concentration and to increase the high fatigue life of prosthesis, stem shape was considered
to be smooth (Oguz Kayabasi 2007; Anthony L. Sabatini 2008). The CAD model was then
modeled in ANSYS 13.0.

Fig 2). 2-D model of the implant (all dimensions in mm)

The material of construct was chosen as Co-Cr, Ti-6Al-4V, 316 L Stainless Steel (SS),
and magnesium alloy AZ91, CF-PEEK, CF-PA 12 and bone. Mechanical properties of the Co-
Cr, Ti-6Al-4V and 316L Stainless Steel (SS) and magnesium alloy AZ91 are listed in table 5.
The mechanical properties of the composite and the bone are listed in table 6. A finite element
analysis was carried out using ANSYS 13.0 on the three dimensional model of the hip joint. In
the present analysis a solid tetrahedral 10node 92 was considered for finite element discretization
of the 3 D model as shown in Figure 3 , which provide good accuracy and formed consistent
mapped meshes(ANSYS 2010). SOLID92 has a quadratic displacement behavior and is well

24 | P a g e
suited to model irregular meshes (such as produced from various CAD/CAM systems). The
element is defined by ten nodes having three degrees of freedom at each node: translations in the
nodal x, y, and z directions(ANSYS 2010). The element also has plasticity, creep, swelling,
stress stiffening, large deflection, and large strain capabilities. The entire model structure was
divided into 6007 elements with 9573 nodes.

Fig 3). Solid 92 Geometry (ANSYS 2010)

Table.5 Material Properties of metals used for the implant

Material Young’s modulus (GPa) Poisson ratio (υ) Density (kg/mm3)

Ti-6Al-4V 110 0.32 4.4x10-6


Cobalt-Chromium 220 0.30 8.5x10-6
316 L-SS 200 0.30 7.9x10-6
Magnesium AZ91 41 0.281 1.74x10-6

Table 5 depicts the material properties of the metals which are used for designing the implants,
Ti-6Al-4V, Cobalt-Chromium and 316 L- Stainless Steel are the most commonly used materials
for the design of the hip implants. Magnesium is the new material which is under research for
use in implants because of the material properties are near that of the bone (Staiger, Pietak et al.
2006). Table 6 depicts the material properties of the composites and the bone which are used in

25 | P a g e
the modeling , composites are the new age materials and has many advantage over the normal
metals (K.S. Katti 2001; Fujihara, Huang et al. 2004; Joa˜o F.Mano 2004; I. Sridhar 2010 ).

Table.6 Material Properties of composites used for the implants

Material Properties Bone CF-PEEK CF-PA

EXX (GPa) 17.9 135.3 15.4


EYY (GPa) 18.8 9.0 15.4
EZZ (GPa) 22.8 9.0 3.5
GXY (GPa) 5.71 5.2 3
GXZ (GPa) 6.58 5.2 3.5
GYZ (GPa) 7.11 1.9 3.2
υ XY 0.26 0.34 0.3
υ XZ 0.31 0.34 0.3
υ YZ 0.37 0.46 0.3

Fig 4). 3D model and the meshed model

Fig 4 shows the volume model which was created using ANSYS 13.0 ,after creating the model
the meshing was done using 10 noded tetrahedral solid element .

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Chapter 4
Results and Discussion

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4. Results and discussion
In this section the results of the static and dynamic analysis are explained. To ensure the
safety of the prosthesis, static and dynamic analysis has been done. Static analysis is carried out
under body weight dynamic walking load to analyze the suitability of the prosthesis for
implantation. Static finite element (FE) analysis was carried out under body weight load and
dynamic effect adds up to 10-20% or more loading to the prosthesis (Oguz Kayabasi 2006).

For static analysis a load of 3kN (F static) with an angle of 20° is applied on the surface
of the implant as shown in the Figure 5 (Oguz Kayabasi 2006). Static loading represents a person
of 70kg (El'Sheikh, MacDonald et al. 2003). An abductor muscle load of 1.25kN (F abductor
muscle) was applied at an angle of 20° to the proximal area of the greater trochanter. An ilio tibia
load of 250 N (F iliotibial-tract) is applied to the bottom of the femur in the longitudinal femur
direction. Distal end of the femur was constrained not to move in horizontal direction.

Fig 5). The models for the static and dynamic analysis with the forces acting on them

Numerical results for static and dynamic analysis are presented in the following sub sections

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4.1 Static analysis of the model

The static analysis of the hip joint using the seven materials discussed in section 4 has
been conducted and the x-component of displacement, y-component of displacement, z-
component of displacement and von Mises stress have been obtained. If the von Mises stress is
less than the tensile strength of the material then the material is said to satisfy the safety
condition. Comparing the von Mises stress with the allowable strength of the material used it has
been found that all the materials satisfied the safety criteria. The distribution of stresses in the
various regions of the hip implant and the displacement are show in the fig 6 to 12 for the seven
different materials. If the displacement is more this may cause the displacement or loosening of
the hip joint prosthesis.(Anthony L. Sabatini 2008; I. Sridhar 2010 )

Fig 6). The static analysis of 316 L SS model, von mises stress, displacement in x-direction,
displacement in y-direction, displacement in z-direction

The results of static analysis of 316 L SS model is represented in Fig 6 it is observed that
the maximum displacement in the x direction is occurring at the head region which is represented
by red color; similarly the maximum displacement in y direction and z direction is also
represented in the figure and can be interpreted from the scale. The maximum von mises stress is
developed in the region where the abductor muscle load is applied. From the figure it can be seen
that the neck region has developed a higher amount of von mises stress of around 140 MPa
compared to the rest of the body.

29 | P a g e
Fig 7). The static analysis of Ti-6Al-4V model, von mises stress, displacement in x-direction,
displacement in y-direction, displacement in z-direction

The results of static analysis of Ti-6Al-4V model is represented in Fig 7 it is observed


that the x , y and z displacement are maximum at the head of the implant this is mainly because
of the load which is being applied at that point . From the figure it can be seen that the neck
region has developed a higher amount of von mises stress of around 137 MPa compared to the
rest of the body.

Fig 8). The static analysis of Co-Cr model, von mises stress, displacement in x-direction,
displacement in y-direction, displacement in z-direction

30 | P a g e
The results of static analysis of Co-Cr model is represented in Fig 8 it is observed that the
x , y and z displacement are maximum at the head of the implant this is mainly because of the
load which is being applied at that point . From the figure it can be seen that the neck region has
developed a higher amount of von mises stress of around 139 MPa compared to the rest of the
body.

Fig 9). The static analysis of Magnesium model , von mises stress ,displacement in x-direction ,
displacement in y-direction, displacement in z-direction

The results of static analysis of Magnesium alloy model is represented in Fig 9, from the
figure it can be seen that the neck region has developed a higher amount of von mises stress of
around 141 MPa compared to the rest of the body.

Fig 10). The static analysis CF-PA 12 model, von mises stress, displacement in x-direction, displacement
in y-direction, displacement in z-direction

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The results of static analysis of CF-PA 12 model is represented in Fig 10 it is observed that the x
, y and z displacement are maximum at the head of the implant this is mainly because of the load
which is being applied at that point . From the figure it can be seen that the neck region has
developed a higher amount of von mises stress of around 132 MPa compared to the rest of the
body.

Fig 11). The static analysis CF-PEEK model, von mises stress, displacement in x-direction, displacement
in y-direction, displacement in z-direction

The results of static analysis of CF-PEEK model is represented in Fig 11. It is observed from the
figure that the neck region has developed a higher amount of von mises stress of around 196
MPa but this region is less than what is observed with other materials

Fig 12). The static analysis bone model, von mises stress, displacement in x-direction, displacement in y-
direction, displacement in z-direction

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The results of static analysis of bone model are represented in Fig 12. It is observed that
the x , y and z displacement are maximum at the head of the implant this is mainly because of the
load which is being applied at that point . From the figure it can be seen that the neck region has
developed a higher amount of von mises stress of around 126 MPa compared to the rest of the
body.

Table.7 The von Mises Stress and Yield Strength of the metals

Material Von Mises Stress (MPa) Yield Strength


(MPa)
Ti-6Al-4V 620 800
Co-Cr 627 720
316 L SS 627 290
Magnesium AZ91 634 150

From table 7 we can see that von mises stress developed in Ti-6Al-4V and Co-Cr is less
than the yield strength of the material. This indicates that the design is safe using these two
materials. In 316 L SS and Magnesium AZ91 the yield strength is lower that the von mises stress
which indicates that the material will fail under the load condition. The stresses which are
developed in the implant can be reduced by changing the design of the hip implant , changes
such as removing the extra metal around the region of low stress density. Different alloy of the
same material with a higher yield strength can also be used for a better safe design of the implant

Table.8 The von Mises Stress developed in composite materials

Material Von Mises Stress (MPa)


Bone 570
CF PEEK 885
CF PA 12 595
From the table 8 we can see that the von mises stress which is developed in CF-PA 12 is
almost near to the value of the stress which is generated in the bone. This shows that the material
is safe for use as implant. Since the stress which is developed in CF-PA 12 is almost near to the
value of Bone the problem of stress shielding can be reduced which will help in better
osseointegration

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4.3 Dynamic analysis of the model

For dynamic analysis a time depended loading as shown in figure was applied on the hip
model. The dynamic forces acting on the hip joint was found from (El'Sheikh, MacDonald et al.
2003)

Fig 13). The graph of the various forces acting on the hip joint prosthesis during one gait cycle

The dynamic analysis results show the response of the hip joint to dynamic loading
condition. Considering the displacement as the model for safety, it can be seen that Magnesium
alloy AZ91 has got the maximum displacement; this can lead to extra motion of the implant
inside the bone structure and cause the displacement of the prosthesis. Co-Cr and 316 L SS,
produced less displacement and hence can be considered to be a safer material for the
construction. Young’s modulus determines the displacement of the material and hence the
selection of material. From the fig 14 and 15 it can be found that CF PA 12 has the von mises
stress which is almost equal to that of the bone , followed by Magnesium alloy AZ 91 , from this
observation we can say that CF PA 12 is the ideal material for the construction as said in earlier
section.

34 | P a g e
700

600

500

Von Mises Stress (MPa)


Ti-6Al-4V
400
316 L SS
Co-Cr
magnesium
300

200

100

0
0 1 2 3 4 5
time (s)

Fig. 14) The variation of Von Mises stress during dynamic analysis by the metals and bone

1000

800
Von Mises Stress (MPa)

600

400
CF PEEK
CF PA
Bone
200

0
0 1 2 3 4 5
time (s)

Fig. 15) The variation of Von Mises stress during dynamic analysis by the composite and bone

From figure 14 and 15 we can observe that the von mises stress in metals and composites
are getting constant after a period of 2 seconds. From figure 14 we can see that the metals have
almost the same amount of von mises stresses developed in them. From figure 15 it can be seen
that the von mises stresses of bone and CF PA 12 are almost similar which indicates that it will
protect the bone from the phenomenon of stress shielding.

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40

35 Ti-6Al-4V
316 L SS

Displacement in x direction (mm)


30 Co-Cr
magnesium
25 Bone

20

15

10

0 1 2 3 4 5
time (s)

Fig. 16) The variation of x-component of displacement during dynamic analysis by the metals
and bone

70
CF PA
60 CF PEEK
Displacement in x direction (mm)

Bone
50

40

30

20

10

0 1 2 3 4 5
time (s)

Fig. 17) The variation of x-component of displacement during dynamic analysis by the
composite and bone
From figure 16 and 17 it can be seen that the displacement which is produced is following the
force applied curve. This shows that the analysis is correct and also it can be observed that the

36 | P a g e
displacement produced in bone and CF PA 12 following each other very closely.

30

Ti-6Al-4V
25
316 L SS

displacement in y direction (mm)


Co-Cr
20 Bone
magnesium

15

10

0 1 2 3 4 5
time (s)

Fig. 18) The variation of y-component of displacement during dynamic analysis by the metals
and bone

60
55
50 CF PA
Bone
displacement in y direction (mm)

45
CF PEEK
40
35
30
25
20
15
10
5
0
-5
0 1 2 3 4 5
time (s)

Fig. 19) The variation of y-component of displacement during dynamic analysis by the
composite and bone

From figure 18 and 19 it can be seen that the displacement which is produced is following the
force applied curve. This shows that the analysis is correct and also it can be observed that the
displacement produced in bone and CF PA 12 following each other very closely.

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0

displacement in z direction (mm)


-20

-40

-60
Ti-6Al-4V
316 L SS
Co-Cr
-80
Bone

-100
0 1 2 3 4 5
Time (s)

Fig. 20) The variation of z-component of displacement during dynamic analysis by the metals
and bone

20

-20
displacement in z direction (mm)

-40

-60

-80

-100

-120

-140 CF PA
CF PEEK
-160
Bone
-180

-200
0 1 2 3 4 5
Time (s)

Fig.21) The variation of z-component of displacement during dynamic analysis by the


composites and bone

From figure 20 and 21 it can be seen that the displacement which is produced is following the
force applied curve. This shows that the analysis is correct and also it can be observed that the
displacement produced in bone and CF PA 12 following each other very closely.

38 | P a g e
From the dynamic analysis we can see that the von mises stresses which are developed in
the implant is less than the yield strength of Ti-6Al-4V and Co-Cr alloy which shows that the
material will be safe under the loading condition. It is also observed that the von mises stress
developed in the Magnesium AZ 91 and 316 L SS is greater than the yield strength of the
material and hence the material will fail under the dynamic loading condition. The von mises
stresses developed in CF PA 12 is almost similar to the bone which is a good indicator that the
material is an ideal candidate for hip joint prosthesis because it will prevent the phenomenon of
stress shielding which is a major cause of hip failure.

From figure 16 to 21 we can see the displacement of the implant in x, y and z direction
using different materials. Here from the graph we can observe that the metal implants have lower
amount of displacement compared to the bone and composites. If the amount of displacement is
high it may cause the loosening of the implant and also can cause the implant to come out of the
joint. This can cause major problem to the patient and also is a major cause for the failure of the
implant. From the graph it can be observed that the displacement of metals is less than that of the
bone. The reduced displacement will cause the mismatch in the movement of the implant and the
bone and can cause the failure of the implant. Composite and bones have an almost similar
displacement graph. It can be observed that the displacement produced in bones and CF PA 12
are almost similar which will help in proper flexibility and movement of the implant in the bone
and also avoid the complications of failure

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Chapter 5
Conclusion and Future Work

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5. Conclusion
The static and dynamic analysis of the hip joint model has been done using finite element
method. From the results and discussions the following conclusions can be made

1. The best material for the construction of the hip implant is CF PA 12 because of the value
of von misses stress which is generated is almost equivalent to that which is developed in
bone

2. CF PA 12 is light weight and is biocompatible and hence is the ideal material for the
construction of prosthesis

3. It was found that 316 L SS and magnesium alloy AZ91 failed because of the von mises
stress which was developed was more than the yield strength of the material. This can be
overcome by changing the design of the prosthesis or incorporating an alloy of better
properties

4. Magnesium alloy AZ91 gets corroded in the body environment and is not an good option
for load bearing implants, but these can be a good option for implants which requires
removal after surgery such as bone plates and nails etc.

5. The CF PEEK is also an option because of it low cost and ease of fabrication. The
material properties of the composites can be easily changed by varying the ply angle and
composition of the composites.

6. By using composite materials we can avoid the stress shielding and have more life for the
implant.

5.1 Future work

Much of the research work is needed in the development and analysis of newer materials for
the construction of the models, materials such as composites and functionally graded materials
are to be studied for the biocompatibility and the mechanical properties. Using MIMICS
software the modeling of the hip joint can be done and hence more studies is required in that
field of modeling. The models have to be tested for fatigue analysis and also for wear rate
measurement.

41 | P a g e
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