One must consider that each patient’s skin represents a unique combination of their DNA,

environment, life- style choices, and product usage.

Patients that exhibit dramatic degeneration of critical matrix components, due to

overexposure to UV rays, smoking and other exogenous offenders, may require more
invasive thera- pies to ameliorate their visible facial degradation.

That said, even patients with advanced matrix breakdown can benefit from the use of
proven topicals to impede further destruction.