a = tHe esseNce of INNOVatION: now frank Hit a Home RUN Inyoymio 908 HE RDARY DRIVER OF Pol Ree Saf Untoty yaks sp of pape hesmple question “What i innovation?” sb yo il gta wide ange of espone, such as: 2 eb! tg saa the sae of 1 Aner rain uh 22.0 uhel ster 1 #80 es mal chs id il siline may hare ened sing ay meting ig a ee ATEN tof lieing poh ee eae tbl anno siealy select and buy a wie variety of books from hore Of eae Seeger mate acsuecsas ae inble pote ro the company. 7 He ny we potent eee acne Le = area eyhaleren pele grliae eee eens atc sc yo OS Eyehbesepleenplanaeadad ering Farnwsth inven «Svc, while Sia ws he ima eeepc gem cient a ree carci ceeded eee Fee ae een aarestes tama erat enh wae ee ete ie etn me ETenper al mers peo camer eh ee peerage Gio eco fr gl a re bods ST ped by sng compre a evEa ot sca eres ny. ‘Cena pl ad Nsom yoarbnnt grenade yr on 7 aan mance ype: Drie mE caer tine peda ames os RSE TASTE ah ape ban ts researc ar donne min Tes maa enn ea cen ma at fe ete sr kh cee caf mst by ring rie cont son ht oman lened—anl sonnei captcha, Thy eo Ba Nana he pet ina Tsfew may engl wih leg inserie a, ote, They el hat employes doo undertand eh fi ofthe company’s Basness and can't demensrae of ipa vlc cngh oy dear mene ‘wget. These managers hive 0 proces in place to eng ns ease reel eee ea eet raat coe eer nese cr eae ‘in eval Ar sane Por prc bt ad ‘entures mien Fank ited me in my ofr. Frank ina a See ee ‘ei ihe waste el ga cae Sees With a and ee ing igo Pan et than aul accent, x combination of Broly” ana sur om of ution, ponsning wads wih nigee sop ‘coded pion sd scenery ache ee coef Frask ask “Do ou know aychng abou bilgy? Whe elt in eld hiss hal rnc we probly atop tha ing wa cng to be sccer wo ine. He lees sxe bene Iw his at sp befor walking fu dh lend ta a opened wo happen a ai sae she lho cece he your ockoowing ay ef hi asked rik what Be wa up ed she han kad ache war bing had ime eign ‘etdinit ade him wha twas. Hesa, “Doyo dP ‘ema huge mls mde up of mary afta fs” “Yar Ind “Dojo ke wy be ed {No nda aight ge el [He tld me thax proteins had to be huge because chey hal a sl) ‘rorcalled abiding site, where chey did their work when inte=tiné ‘eh ote potin. Althowe atoms in the molecule were nee! P= ‘cause the binding sit had to be very specific in what it did, Ovi Tega emerceet coma snas se le ote etter einen me 86 re te, 8 Br pois wold annet wih ne auc te abies (rub fnction, “The mate sei oul undeseding ‘he impeaions of ae he wa Frank went onto sy tat Something ase rung with oe of your protis, yt havea lan, you nada to the ee ‘iv prea. The peblem at dag any moles compre ith psne. They mt atch ema to ey che vit ple fa rica proc do tee. Andro make ths ate, he rug states el way oer pen our aly, may cue ide ec Thee eo cera males ba develop ge Yon mur rhe broken poe and ones with any ers Ds evlopcot ike wating eto ball enn with 10,00 ws awa pectts and ein td th ote pon wb wl Beso eewithyuand nore che Ths wis ew drapcen ake lion (Syed fen year ep ny i finding eden sac “his ws ict, Lashed, "What your ea” etd, “By aelaon compute can design sal males thot wil aac hemes the rah placeom roi ofthe probes “Wow: Ishugh, iis rey important problem” On my bck eter we shld ppt prope, Fk aust ihe k= ft fb cold do chs, wold bes huge corbin to medicine "The quan wt "Could Fak rely do hs” Whar he wa ecb ing was yer ical calelaton—maybe imposible Task Fan (exp is appeach, bot we die ge vey ft Like ming bila people. Fak sumed others knew as mich he ier did't Ad fen eve at this ping, ic ie aie ‘more questions thn ic anwesd. Fo example, Lake Fk about Competing apposche. Hedda know of gy dict competition, ae thong ken fm ps experience ha there is abays competion ‘Ar this pint had ogo toa sng Frank asked, “What shold de peat te up nude page ep and come bck i a ons” ‘No Tid. "Why don you comeback at even tonight ad esen to tbe for gueions that deine your vale ‘vem Frank throm tha wold supe im by ingwha ae se four questions” Prank asked, Va, Wht the mth md? Wha is 3 rac ay hind? What re the eg orcas of your appre aa he And ‘hoe beets er cous compare withthe compte” |e at de treed to the fut goestons 2 “value proposition” 'NABC" for asd, appre, eae sp oss, ao ne ne Sea ae ‘Frank said, “Okay.” . ee ree oleae ene er soe eee make his idea a success. ae ‘corporate responsibility, engagement in the process to create a comm, oe ee. eine Menreereee e el tdi ae aan tere eerie eens Seieme ape sgee nen arenes eee scien : ap nt ingens kan: meee ov ome te Thy always ar Speling out aiden osha a buy pe auc on of the roughest challenges inthe eal tages 80% moa eomcerhvincenral hie lars eh ‘cml tion en fn rt ++ value proposition clear, ‘Bur ie was a scar, we had begun 24 Fea ase ommaing Heeane ck sud pom le=h at Scien, ideas were expressed ile more clearly, Frank inroce! a ‘0 aoter rec collage, Joho Kalp. This wat big step frwor [Now we hd wo peopl who fal el konwleige i the eld plat sme Leonibuted knowlege ofthe dpi proces we hal to go tre and what he answer ues eed oak ike shen we mete done ‘Over ime we gated ter cal collegues Fok ake so ncedf pepe, ierced with ots clint at tei ate ‘sad constantly impoved aed eed hs NABC alc ropenton Temisquitean experience Bsr" in the ld ld Faker i eas were impose. They gone hi, eee hia woes sled his. Bo nk malay pect and persevere 1 neve nd tsk Fa agus nthe champion Hs passin sox one ad, fers fr ae renin pth wa on hi wy. Hedda aie Te tok Fak and his eam oer yea of challenging work, When swe seed the prices, hd sed in wha is oul was. Hes") areca poet with fning offhand und dol {yar ue wold ike. mac ee an that” Tri," think wean Frankel Brame founding men er in an exciting new company, Lec Parmaceaticls? with & alimilion doll esac program aed with sme of he bs people inbiseld Jamra, earned many fee sls ad the dis- ‘pln ned o cae sical ovations ee and owe gain Since its formation Lacs ht Mae emasable progres. At oo pin Fank nd iscollegues tk fr $40 milion ew capital nd they eventual decid o ae $80 milion —disaca ie when most ‘nga wete ving ole atecng $10 milion invent capi tal The aso forte eceren ada Loca a doing something Import hath neve been de desing anew devs comply ina compares This development hes the potetal of enoving many ‘eas of milion of las rom he ast deg development we hing the development ime yas tsfomationaineoaton ‘Vocus nom has sever poenti bleckbuster drags dha are don lial alsin cance od inaadon—rwo vitally important tes of medicine. Thee aaringacieremens were sr in motion withthe