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After reviewing these notes don’t forget to take the quiz that contains tetralogy of fallot
NCLEX questions and to watch the lecture.
The word tetra or tetrad (tetralogy) means it’s a condition that consists
of FOUR problems.
Aorta displacement
Pulmonary stenosis
To understand tetralogy of fallot, let’s talk about NORMAL blood flow because then the
defects make complete sense.
1. The un-oxygenated blood (this is blood that has been “used-up” by your body that
needs to be resupplied with oxygen) enters to the heart through the SUPERIOR
AND INFERIOR VENA CAVA.
2. Blood enters into the RIGHT ATRIUM
3. Then it is squeezed through the TRICUSPID VALVE
4. Blood then enters into the RIGHT VENTRICLE
5. Then it is squeezed into the PULMONIC VALVE
6. Blood is then shot-up through the PULMONARY ARTERY and then enters into the
lungs for some oxygen
Left Side of the Heart (goal of this side is to get the richly, oxygenated blood to the
body to feed the brain, tissue, muscles, organs etc.)
7. Blood enters from the lungs through the PULMONARY VEIN that has just been
refreshed with oxygen to go
8. into the LEFT ATRIUM
9. Down through the BICUSPID VALVE (also called mitral valve)
10. Then blood is squeezed into the LEFT VENTRICLE
11. Up through the AORTIC VALVE
12. Lastly up through the AORTA, where it pumped throughout the body
Tetralogy of Fallot
Blood Flow:
Let’s start on the right side:
As blood enters in from the superior and inferior vena cava it goes into the right atrium,
down through the tricuspid, and then the left ventricular
But we have a problem at this point and it’s called a VENTRICULAR SEPTAL
DEFECT (VSD).
This is a fancy word that means there is a hole in the ventricular wall. Normally
this wall separates the RIGHT and LEFT ventricle, but in TOF the blood is
mixing….this is a problem because we will have exhausted, unoxygenated blood
mixing with fresh oxygenated blood.
Unfortunately, the problem doesn’t stop here. The blood that is in the right ventricle has
a strong desire to reach the lungs to get oxygenated. To do this, it must go up through
the pulmonic valve and pulmonary artery.
Activity (feeding, crying, playing) causes cyanosis “TET spells”… cyanosis, shortness
of breath, increased breathing, fainting…think “activity intolerance”
Nurse’s role with a “Tet spell”: knee-to-chest position, calm infant, and apply
oxygen. Patient may need medication to calm or to increase systemic vascular
resistance (IV fluids etc.)
Fingernail changes (clubbing due to hypoxia) noticeable at about 6 months
Fatigues or faints easily (especially during a “tet spell”….due to low oxygen levels)
Lift knees-to-chest position or squatting (children) WHY? squatting and the knee-to-
chest position increases systemic vascular resistance, which will decrease the
right to left shunting in the ventricles and helps increase oxygen levels.
Trouble feeding and thriving (not gaining weight, small for age, doesn’t achieve
developmental milestones etc. )…think “failure to thrive”
Temporary surgery is performed to help with cyanosis and improve blood flow. It can
include shunt placement to shunt oxygenated blood through the heart so oxygen levels
are increased or stent placement to open up the stenosis. In addition, complete repair
can be performed when the child is older enough to tolerate surgery (about 6-12 months
of age). This includes placing a patch over the septal wall defect to prevent blood mixing
in the ventricles.
If a child has a severe case of TOF, where there is a severe defect to the pulmonary
valve (blood won’t be able to get to the lungs) and the newborn is very cyanotic at birth,
a temporary surgery may be performed and a prostaglandin infusion started.
Aprostadil (prostaglandin E) will keep the ductus arteriosus open (this normally closes
shortly after birth) to allow more blood to flow to the lungs for oxygenation.
References:
Congenital Heart Defects | National Heart, Lung, and Blood Institute (NHLBI). (2018). Retrieved from https://www.nhlbi.nih.gov/health-
topics/congenital-heart-defects
Tetralogy of Fallot Facts | Congenital Heart Defects | NCBDDD | CDC. Retrieved from
https://www.cdc.gov/ncbddd/heartdefects/tetralogyoffallot.html
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