ABSTRACT

Osteoporosis is a bone disease that occurs when bone density decreases as well as the
damage of bone architecture that weakens the strength of bones; in this case, it is bone loss, which
can lead to increased risk of fracture. The research method used in this present study was
interviews and observations which conducted at the Sakinah Islamic Hospital in Mojokerto. It was
found that the number of people who suffer from osteoporosis in the last two years have increased.
Osteoporosis patients are mostly older women due to lower levels of the hormone estrogen that
affects the bone metabolism. The patients are given a prescription of chemical drugs that require
a cost which is more than one million rupiah for a month of treatment. That led us to do this
research in order to help people reduce the cost of the treatment. Marsilea Crenata or water clover
is a water-nail plant and lives wildly in Surabaya, East Java, which contains isoflavones that can
prevent osteoporosis. A research which was conducted by Salma (2016), proves that the leaves of
Marsilea Crenata have passed the pre-clinical test on mice that were used as an analgesic activity
test for 80% ethanol extract and it is supported by Trisunuwati (2016) who claimed that the
distillation of water clover leaves can increase estrogen levels in the blood of the animal model.
The previous studies underlie the creation of our product innovation, namely marsilea crenata
jelly candy. The jelly candy was chosen because of its chewy shape, sweet taste, and attractive
color; consequently, it can be accepted by the public. This jelly candy does not have side effects if
it is consumed regularly since it is made from natural ingredients. A further research needs to be
done thus marsilea creanata jelly candy can be an alternative treatment for osteoporosis.

Keywords: marsilea crenata, osteoporosis, a jelly candy, water clover.