(B.

Pharmacy 3" Year-Supplementary)

PHARMACEUTICS-VII
(Physical Pharmacy)
(2008 Batch) BPH-303
Note: Attempt any five questions. All questions carry equal marks.
0.1 Discuss the factors miiuencing the P� of buffer solutions. What is buffer
capacity & how can it be determined?
Q.2 Describe chelates and their physical properties. What differentiate them from
organic molecular complexes? What type of forces hold
such complexes togethef? Explain with illustrations.
Q.3 What are various physical degradation methods of pharmaceutical products?
Identify their causes and remedial measures.
Q.4 What is solubilization and detergency? Underline and discuss the adsorption at
liquid interfaces.
Q.5 Define and calculate two sedimentation parameters, sedimentation volume and
degree of flocculation. How can these properties vary &
affect the stability?
Q.6 What are various derived properties of powders? Describe the relevance and
applications of various types of densities and
bulkiness for the pharmaceutical dosage forms.
Q.7 Differentiate between the flow properties and corresponding rheograms between
Newtonian and non-Newtonian materials. Relate
them to relevant phannaoeutical dosage forms.
Q.8 Enumerate various derived properties of powders. Describe the evaluation and
relevance of Compessibility Index, and Porosity.