MR, TD & HPV VACCINE

SCHOOL BASED IMMUNIZATION

 Introduction
To generate vaccine-mediated protection is
a complex challenge. Their early
protective efficacy is primarily conferred by
the induction of antigen-specific
antibodies.
 WHY SCHOOL BASED
IMMUNIZATION?
• Booster doses maybe needed to ensure
that high levels of protection are
maintained
• New vaccines such as the human
papilloma virus (HPV) vaccine are more
effective if delivered at a specific age.
 Cervical cancer, human
papillomavirus (HPV)
World wide, almost 500, 000 women
develop cervical cancer and 274, 000 die
from the disease every year. Cervical
cancer is caused by certain types of
Human Papillomavirus (HPV) and is the
most common cancer affecting women in
developing countries (WHO 2007).
The age-standardized cervical cancer
incidence rate in the Philippines is 20.9
per 100,000, which is 30% higher than the
world rate (Ferlay et al., 2004).
 HPV VACCINE
Vaccination of HPV vaccine is one of the
preventive interventions for the cervical
cancer in the later life. WHO recommends
that primary intervention begins with HPV
vaccination of girls ages 9-13 years old,
before they become sexually active.
 HUMAN PAPILLOMA VIRUS
VACCINE
• These include two types that cause about
70% of cervical cancer and two types that
cause about 90% of genital warts. HPV
vaccine can prevent most genital warts
and most cases of cervical cancer.
• Protection from HPV vaccine is expected
to be long-lasting. But vaccinated women
still need cervical cancer screening
because the vaccine does not protect
against all HPV types that cause cervical
cancer.
 SPECIFIC GUIDELINES
VACCINATION FOR HPV VACCINE:
•Only 9-10 years old female student shall be
vaccinated with 2 doses of the quadrivalent
Human Papilloma Virus (HPV) vaccine in
the designated immunization post in the
school.
 Why is HPV vaccine given to
girls at this age?

• It is important for girls to get HPV vaccine

before their first sexual contact -- because
they have not been exposed to HPV. For
these girls, the vaccine can prevent almost
100% of disease caused by the four types
of HPV targeted by the vaccine.
 TETANUS
• Potent bacterial neurotoxins
originating from vegetative
C. tetani may cause local
muscular spasms or
generalized tetanus.
Untreated generalized
tetanus is often fatal
• It causes painful muscle
tightening and stiffness,
usually all over the body.
Tetanus is one of the vaccine-
preventable diseases included in DOH’s
Expanded Program on Immunization
 DIPHTHERIA
It is a potentially fatal, contagious
disease that usually involves the nose,

throat, and air passages, but may also

infect the skin.
• It can lead to breathing problems, heart
failure, paralysis, and death.
• Both diphtheria and tetanus are
infections caused by bacteria.
• Diphtheria spreads from person to
person through secretions from
coughing or sneezing.
• Tetanus-causing bacteria enter the
body through cuts, scratches, or
wounds.
 Tetanus-Diptheria (TD)
VACCINE
Why get vaccinated?

•Tetanus and diphtheria are very serious

diseases. TD vaccine is used to protect
adolescents and adults from both of these
diseases.
• 3 doses of
diphtheria/tetanus/pertussis vaccine
in infancy

• Tetanus-toxoid (TT)-containing booster at

school-entry age (4 to 7 years old)

• TT-containing booster in adolescence (12

to 15 years old)

• TT-containing booster in early adulthood

• TD vaccine can protect adolescents and
adults from tetanus and diphtheria. TD is
usually given as a booster dose every 10
years but it can also be given earlier after
a severe and dirty wound or burn.
MEASLES
Measles is mostly a mild disease
of young children,
characterized by fever, cough,
nasal congestion and a typical
rash.

Primarily by airborne respiratory

droplets. The virus is highly
contagious. (WHO 2012)
 RUBELLA
Rubella is usually a mild childhood disease
characterized by moderate fever,
lymphadenopathy and a rash. In adults,
transient arthralgia and arthritis may occur.
Rubella infection in early pregnancy often
results in miscarriage, stillbirth or multiple
fetal defects (WHO 2012).
 Measles-Rubella Vaccines
Measles is a live attenuated vaccine:
available either in monovalent form
(measles component only), or in fixed
combinations with one or more of vaccines
against mumps, rubella and varicella. Two
intramuscular doses are administered at
an interval of at least 4 weeks.
 TARGET POPULATION
HUMAN 9 - 10 years
GRADE PAPILLOMAVIRUS old, Female
4 (HPV) VACCINE
*Will undergo screening
TETANUS-DIPHTHERIA on past MCV
immunization history
GRADE (TD) VACCINE
*All will be vaccinated
1 MEASLES-RUBELLA (MR) with TD regardless of
VACCINE immunization history.

TETANUS-DIPHTHERIA *All will be

GRADE (TD) VACCINE vaccinated with
MEASLES-RUBELLA (MR) TD regardless of
7 VACCINE immunization
history.
SCHEDULE FOR GRADE 1
TETANUS-
MEASLES-RUBELLA
DIPHTHERIA (TD)
(MR) VACCINE
VACCINE

DOSAGE 0.5 ml 0.5 ml

ROUTE & SITE OF Subcutaenous, Right Deep Intramuscular,

INJECTION Deltoid arm Left Deltoid arm

#DOSES REQUIRED 1 dose

STUDENT WITH 2 doses with 28 days

ZERO DOSE MCV interval
STUDENT WITH
1 dose only
ONE DOSE MCV
 SPECIFIC GUIDELINES
• All the teacher in charge of grade 1 shall
check the measles immunization of each
student. The immunization card of each
student shall be requested from the
parents/guardians/caretakers and shall be
the proof of evidence that student received
the measles vaccines.
SCHEDULE FOR GRADE 7

TETANUS-
MEASLES-RUBELLA
DIPHTHERIA (TD)
(MR) VACCINE
VACCINE

0.5 ml 0.5 ml
DOSAGE

ROUTE & SITE OF Subcutaenous, Right Deep Intramuscular,

INJECTION Deltoid arm Left Deltoid arm
Some people should not get this
vaccine
• A person who has ever had a life-
threatening allergic reaction after a
previous dose of any tetanus or diphtheria
containing vaccine, OR has a severe
allergy to any part of this vaccine, should
not get Td vaccine. Tell the person giving
the vaccine about any severe allergies.
DOH will give the tetanus-diphteria
(TD) vaccine to grade 1 students
starting August.

In addition to this, grade 7 students

will also get vaccinated against
measles, rubella, tetanus, and
diphtheria (MRTD).
Garin said giving TD and MRTD
vaccines to students is crucial,
especially in a disaster-prone country
like the Philippines.
On top of the 3 doses of tetanus
vaccine given during the first year of
life, the booster shots to be given as
children reach grades 1 and 7 "will
give...lifetime immunity during
calamities."