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Eye-tracking-based assessment suggests preserved well-being in locked-in patients.
Linse K, et al. Ann Neurol. 2017.
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Abstract
We assessed quality of life (QoL) and psychological well-being in patients with amyotrophic
lateral sclerosis-induced locked-in state and their next of kin in a fully unbiased manner using eye-
tracking computer systems. Eleven of 30 screened patients and 9 next of kin completed study
procedures. Patients reported good QoL, which appeared to be at the cost of the QoL of their next
of kin. Next of kin rated their own or patients' QoL similarly, but they identified different areas as
important as compared with patients. Our results are of importance for the discussion of end-of-
life decisions and the evaluation of patients' presumed wishes as well as for psychosocial
interventions. Ann Neurol 2017;81:310-315.

© 2017 American Neurological Association.

PMID 28074605 [Indexed for MEDLINE]
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Comment in
Ann Neurol. 2017 Sep;82(3):491-493.
Ann Neurol. 2017 Sep;82(3):490-491.
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