The nephrotic syndrome is caused by renal diseases that increase the

permeability across the glomerular filtration barrier. It is classically

characterized by four clinical features, but the first two are used
diagnostically because the last two may not be seen in all patients:

 ● Nephroticrangeproteinuria−Urinaryproteinexcretiongrea
terthan50 mg/kg per day
 ● Hypoalbuminemia−Serumalbuminconcentrationlesstha
n3g/dL(30 g/L)
 ● Edema
 ● Hyperlipidemia