Heart

The heart contracts at different rates depending on many factors. At rest, it might beat around 60
times a minute, but it can increase to 100 beats a minute or more. Exercise, emotions, fever,
diseases, and some medications can influence heart rate. For more information on what is
"normal,".

The left and right side of the heart work in unison. The right side of the heart receives
deoxygenated blood and sends it to the lungs; the left side of the heart receives blood from the
lungs and pumps it to the rest of the body.

Kidney
Angiotensin II exerts a vasoconstrictive effect on both afferent and efferent arterioles, but
because the efferent arteriole has a smaller basal diameter, the increase in efferent resistance
exceeds the increase in afferent resistance. Afferent vasoconstriction is further minimized by
angiotensin II–mediated release of vasodilatory prostaglandins and nitric oxide. In addition,
angiotensin II can constrict the glomerular mesangium, thereby reducing the surface area
available for filtration.
The net effect of angiotensin II on filtration invokes the opposing factors of reduced renal blood
flow and mesangial surface area (causing a decrease in filtration) and the increase in glomerular
capillary pressure (which tends to increase filtration).