- Blood type = screening - Administration Transfusion o 1-2 mL/min - Administration of any blood products o 5 minutes per single donor bag Blood transfusion o Given rapidly - Lifesaving therapy, medical and surgical - Platelet derivatives conditions in need of blood o Separating and freezing the plasma o Plasma expander within 8 hours o Hemorrhage o Uses National blood service act 1994 Multiple coagulation factor - Republic act 7719 derivatives - Act, voluntary blood donation, safe blood Warfarin - Eligible donors DIC o 18 Massive transfusion o 110 lbs (50 kg) administration o Skin diseases Cryoprecipitate – shelf o 56 days life of 1 year o HBG 12.5 gl/dl – women o System 13.5 gl/dl – men fibrinogen - Ineligible donors o Chemotherapy o HIV or AIDS o DIC o Illegal drugs – IV o Massive o Sex, prostitutes – past 12 months hemorrhage o Hepatitis o Hemophilia o Cancer Administration of blood component o Received clotting factor, concentrations 1. Recipient consent Blood collection methods 2. Verifying authorized prescribers order - Unrelated donor – allogeneic 3. Pretransfusion - Directed donor 4. Vascular access; selecting and preparing the - Autologous donor (self) equipment o Blood donor resources o Increase temperature = hemolysis Blood components therapy o Cold infusion = venous spasm - Whole blood – RBC, plasma, WBC, platelets 5. Preparing the patient - 500 mL, 200 mL of RBC and 300 mL of plasma 6. Dispensing and transportation with 33% HCT 7. Initiating the transfusion - Acute, massive blood loss w/ s/sx o Prescriber’s order o Hypotension o Transfusion consent form o Dyspnea o Recipient o Tachycardia o Unit o Pallor o Blood type Administration o Expiration RBC o Compatibility - 2500350 mL o Appearance - 20-30% plasma, leukocytes, platelets 8. Monitoring the transfusion Washed RBC 9. Completing the transfusion - Severe allergic reactions Documentation - Wash w/ cellular saline 1. Medication order Irradiated blood products 2. Consent - Transfusion associated GVHD 3. Name/type o Leukemia/lymphoma 4. Donor unit o Bone marrow 5. Date and time o Cell transplant 6. VS o Immunodeficiency 7. Volume transfused o Neonate and low birth weight infants 8. Transfusionist Platelets 9. Adverse effects - 100,000-300,000 Complications - Room temperature 20-24 C 7 days Acute hemolytic + transfusion reactions - Single apheresis unit = 6-8 random donor Signs and symptoms platelets - Fever and tachycardia Blood transfusion therapy - Mild - Severe - Red/dark urine - Shock/DIC Interventions - Droplet recognition - Stop infusion - Discontinue tubing - Notify physician/blood bank - VS - Furosemide Febrile nonhemolytic febrile reactions Signs & symptoms - Fever - Chills - Headache - Vomiting Interventions Allergic reactions - Allergic to the component or less often by antibodies from an allergic donor o S/SX: Mild – itching, hives, urticarial, angioedema, deep swelling around the eyes/hips Severe – anxiety, bronchospasm, wheezing, hypotension o Interventions: Stop the transfusion Keep the vein open with normal saline Notify physician Monitor VS Antihistamines Anaphylactic reaction o Preventions: Mild reaction Transfusion related acute lung injury Transfusion associated circulatory overload