NAME OF ADVERSE NURSING

CLASSFICATION MECHANISM OF INDICATION CONTRAINDICATION

DRUG EFFECT CONSIDERATION
ACTION
Mucolytic Bind either nonselectively to Liquefaction of secretions in Caution should be used in GI: Nausea, vomiting, Assess for possible
Generic central and peripheral histamine, high-risk respiratory patients cases of acute bronchospasms, anorexia. contraindications and cautions:
Name: (H,) receptors or selectively to who have difficulty moving peptic ulcer, and esophageal any history of allergy to the
acetylcysteine peripheral H, receptors, causing secretions including varices because the increased CNS: Headache, drug; persistent cough due to
either CNS stimulation or postoperative patients (e.g., secretions could aggravate the dizziness. smoking, asthma, or
depression patients with tracheostomies problem. emphysema, which would be
Brand name: to facilitate airway clearance Acetycysteine is a preganancy Underlying cough: The cautions to the use of the drug;
Mucomyst, and suctioning). risk category B medication. most important and very productive cough,
Pulmozyme Clearing of secretions for This medication should not be consideration in the use which would indicate an
diagnostic tests (e.g., used in client at risk for GI of these drugs is underlying problem that
diagnostic bronchoscopy). Hemorrhage. discovering the cause of should be evaluated.
Dose: Used orally to protect the Use cautiously in client who the underlying cough;
10%; 20%; 600 mg; 500 liver from acetaminophen have peptic ulcer disease, prolonged use of the Perform a physical
mg; 2.5 g. toxicity. esophageal varices, and severe OTC preparations could examination to establish
Treatment of atelectasis from liver disease. result in the masking of baseline data for assessing the
Route: thick mucus secretions. Due to the potential for important symptoms of a effectiveness of the drug and
Instilation inhalation bronchospasm, acetylcysteine serious underlying the occurrence of any adverse
should be used cautiously in disorder. effects associated with the
client who have asthma drug therapy.
Respiratory: Rhinorrhea,
bronchospasm. Assess the skin for the
presence of lesions and color
Skin: Rash. to monitor for any adverse
reactions.