Teste utilizate in Dg bolilor infectioase

I Investigatii uzuale

HLG
- neutrofilie - inf bacteriene
- neutropenie – inf bact severe, BGN
- limfopenie – HIV, TB, infectii virale (gripa)
- limfocitoza/ limfomonocitoza – inf virale
- eozinofilie – inf parazitare

- anemie – hemolitica – EI, malarie, Cl perfringens

- centrala – Parvo B19, HIV, TB

- trombocitoza – inflamatorie
- trombocitopenie – CID sepsis sever, Ac antiplachetari (VHC), hipersplenism
(ciroza)

Sdr inflamator
VSH, Fg, PCR, procalcitonina

Teste biochimice
- TGP
- Enzime de colestaza - angiocolita
- Retentie azotata – sdr diareic, sdr hepatorenal, toxicitate medicam
- Ionograma – sdr diareic
- Sumar de urina – sdr nefritic/nefrotic; ITU

Teste imagistice
- Rg
- eco abdominal
- eco cord
- CT, RMN

Lichide biologice – LCR, ascita, pleural

- glucoza↓ - inf bacteriana
- proteine – exudat, transsudat
- celularitate – PMN, Ly

Teste de evidentierea directa a agentilor etiologici

- frotiu – Gram, Giemsa, Ziel Nielson
- imunofluorescenta directa – PCP, Chlam trachom, Bord. Pertussis
- culturi – uzuale, anaerobi, Lowenstein, Sabouraud, selective (Loffler - difterie)
- culturi celulare - virusuri
Ag solubile – CIE, Elisa, Latex aglutinare
- Mg, Pn, Hib, criptococ – LCR
- Legionella - urina
PCR – ser, lichide biol, tesuturi biopsiate
- Dg – HSV, CMV, TB, Toxoplasma
- Prognostic+monitorizarea terapiei – HIV, VHB, VHC

Teste de Dg indirect - serologice

- IgM – inf acuta/recenta
- IgG – inf veche – cronica sau vindecata
- Teste de aviditatea IgG – Toxo, CMV, Rubeola – gravide
!! sensibilitate / specificitate
!! reactii incrucisate – Ex HIV/EBV, CMV

Western blot/imunoblot – teste de confirmare – HIV, Toxo, Borellia, etc