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STEP 1 REVIEW COURSE – Part 1, Set 28

1. What physiology accounts for the automaticity of the AV and SA nodes? (FA13 p260) (FA14 p275)
(SU14 p64-65) (Phys p111-112)

2. What test is used to detect corneal abrasions?

3. A patient with an epilepsy diagnosis is pregnant with her first child. She is concerned that her child
may also have seizures. What are the most common causes of seizures in children? In adults? In the
elderly? (FA13 p445) (FA14 p485) (SU14 p46)

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STEP 1 REVIEW COURSE – Part 1, Set 28
4. What is p value? What is an acceptable p value? (FA13 p54) (FA14 p57) (SU14 p21)

5. What organism causes Hansen disease? What animal serves as the reservoir for this organism in the
US? Where in the body does this organism live? (FA13 p133) (FA14 p135) (SU14 p460-461)

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STEP 1 REVIEW COURSE – Part 1, Set 28
6. Which diuretics lower serum calcium levels? What is the mechanism by which this patient developed
hypocalcemia? (FA13 p500-501) (FA14 p547-548) (SU14 p166-167)

7. A 9-year-old child is brought into the clinic for evaluation of a right wrist drop and confusion. Physical
exam reveals a bluish line on the gingivae. What peripheral smear finding is consistent with lead
poisoning? What is the treatment for lead poisoning in this patient? (FA13 p350, 353) (FA14 p380,
383) (SU14 p281)

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STEP 1 REVIEW COURSE – Part 1, Set 28
8. What is BNP, and how is it useful in cases of heart failure? (FA14 p279) (H p2216)

9. A kidney transplant patient begins to experience renal failure seven years after receiving her kidney
transplant. What type of rejection is this, and how is it mediated? (FA13 p208) (FA14 p214) (SU14
p267)

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STEP 1 REVIEW COURSE – Part 1, Set 28
10. A 62-year-old man complains of weak urine stream and hesitancy when trying to urinate. His physician
prescribes finasteride. How does this agent treat benign prostatic hyperplasia? (FA13 p539) (FA14
p591) (SU14 p219, 225) (GG p1205)

*Page references are as follows:

FA13: First Aid for the USMLE Step 1 2013


FA14: First Aid for the USMLE Step 1 2014
SU14: Step-Up to USMLE Step 1 2014
R: Robbins and Cotran Pathologic Basis of Disease, 8th ed. (2010)
Phys: Guyton and Hall Textbook of Medical Physiology, 12th ed. (2011)
H: Harrison’s Principles of Internal Medicine, 18th ed. (2012)
COA: Clinically Oriented Anatomy, 6th ed. (2010)
GG: Goodman and Gilman Pharmacological Basis of Therapeutics, 12th ed. (2011)

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