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epithelial tumors of the ovary have been


i controversial for over a century, in spite of the
o acceptance of a borderline category in almost
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i all current classifications of ovarian tumors.
Typically, borderline tumors are noninvasive
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l neoplasms that have nuclear abnormalities and
Outcome and reproductive funct
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n mitotic activity intermediate between benign and after conservative surgery for
malignant tumors of similar cell type. Borderline
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t tumors of all surface epithelial cell types have
borderline ovarian tumors
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o been studied. The most common and best
Robert T Morris, David M Gershenson, Elvio
f understood are serous borderline tumors and
s Silva, Michele Follen, Mitchell Morris, J Tayl
mucinous borderline tumors of intestinal type,
u Wharton
r which are the subject of this review. Some of the Obstetrics & Gynecology 95 (4), 541-547, 20
v most challenging issues for serous tumors
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v
include: the criteria and clinical behavior of Objective: To study reproductive function an
a stromal microinvasion; the high prevalence of disease outcome in women with borderline
l synchronous extraovarian disease; the
o ovarian tumors who were treated with
f classification and histopathologic features of conservative surgery.
p associated peritoneal tumor implants, especially
a invasive implants; and, the prognostic Methods: Patients with borderline ovarian
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i significance of micropapillary tumors. The tumors were identified from institutional
e mucinous borderline tumors of intestinal type databases. Patients were eligible if they had
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have a different set of considerations, including: pathologically confirmed borderline ovarian
s their frequently heterogeneous composition with tumors, no prior sterilization, no history of
w coexisting benign, borderline and malignant radiation therapy, retained their uterus and
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elements; the classification and significance of ovarian tissue, and were younger than age 4
h accompanying noninvasive carcinoma; the Information was acquired by retrospective
m recognition of stromal invasion, including medical record review and patient interview.
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c microinvasion and expansile invasion; and, the
i historically misunderstood relationship to Results: Forty …
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