description of progression Current flair up: Psoriasis gradual or sudden, where it first appeared, Topical Therapy Patho changes in severity over Chronic Autoimmune time, Anti-inflammatory Langerhan’s Overstimulation&ofsuppress cell Cells are fever and itching division Skin cells are produced faster than present they can be shed Corticosteroids inflammation Shedding o When prescribed occlusive Normal basalinc. dressings cells 28 days absorption oPsoriasis Teach:cell division avoid face, scalp,4 to 5 days skinfold areas Tar Preparation o MESSY, staining & odor Anthralin o Strong irritant can cause chemical burns o Teach: Don’t leave on to long, wash off after each use, check for local tissue reaction, do not apply to surrounding skin Calcipotriene o Synthetic Vitamin D (regulates cell division) Tazarotene o Derivative Vitamin A (slows cell division & dec. inflammation) o Teratogenic: teach strict contraceptive measures