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Table II: Summary of all the studies included in the literature review
Reference: The aim of the study Study design Date of Site of Sample size Sample criteria Methodology applied in Results/ outcomes [could be
data recruitment the Intervention/ control divided to two rows for
recruit group cases vs. controls]
ment
To investigate if parental Cohort study Not community centers in 142 parents Inclusion criteria: be A video tape was digitized Hispanic parents rated VC most
(E. Angeles background affects mentioned Indianapolis, parents of a child under and loaded onto a tablet acceptable, followed by TSD,
Martinez Mier acceptance of behavior Indiana University age eighteen, be over age device and used to show PR, and pharmacologic
et al., 2019) guidance techniques School of Dentistry 18 themselves, and be of the different techniques: techniques.
Hispanic ethnicity, non- (AR), (GA), (N2O), (OP),
Hispanic Black, or White (TDS), (VC) and (PR) Black and white parents rated
TSD, followed by N2O, as
No exclusion criteria most acceptable, and AR and PR
as least favorable
(Al Zoubi L et To investigate the parental cross- July 2016 1-University of 136 parents Inclusion criteria are Parents bringing their The acceptance of all advanced
acceptance of advanced sectional study -December Greifswald parenthood, literacy and children for dental care BMT was significantly higher
al., 2019) behavior management 2016 2-University of Berlin enthusiasm to participate answered a questionnaire on when the treatment was urgent.
techniques used in pediatric 3- University of the acceptance of four
dentistry in normal and in Leipzig Exclusion criteria are advanced BMT. Nitrous oxide sedation was rated
emergency situations in 4-University of parents of children with as the most acceptable technique in
Germany Dresden special both normal and emergency
5-University of Mainz health care needs situation.
(Heinrich M et investigated the feasibility and Not mentioned Not (LIVOPAN, Linde 210 children Children (ASA 1) were • Assessment of pain A N2O/O2 (50:50) mixture was
al., 2015) the effectiveness of mentioned Healthcare, included in the study. before, during, and after administered in 210 children.
N2O/O2 (50:50) as a Germany) Exclusion criteria were the intervention through a Three treatments were
sedative analgesic when traumatic brain injuries, self-assessment using the terminated because of lack of
performing minor surgical otitis media, bowel facescaleof Hicks et al12 compliance, nausea, or
procedures. obstruction, gastrointestinal with a score of 0 (no pain) dizziness. No other side effects
disorders, or facial to 10 (strongest pain); were encountered. During the
lacerations. , children in • Evaluation of the child’s intervention, 80.5% of all
emergency situations behavior: relaxed and patients were pain free, and
calm, crying, shows 81.9% were relaxed and calm. A
defensive reactions or higher rate of insufficient pain
additional restraint control was observed when the
needed indication was an injection of a
• Inhalation time of the digital block or a reposition of
N2O/O2 (50:50) mixture; fractures and dislocations
• The lowest oxygen
saturation during the
application of the
(S To evaluate the efficacy and RCT 2001 Not mentioned 90 children. Exclusion criteria included Nitrous oxide was OSBD scores reached a
Kanagasundara safety of nitrous oxide for Jun impaired level of administered at a maximum during the
m et al., 2001) children undergoing painful consciousness, variable concentration induction phase with lower
procedures. undrained pneumothorax, of 50±70%to achieve a scores during subsequent
recent middle ear surgery, level of consciousness. phases.
and a difficult airway. two observers were Children over the age of 6
Patients were fasted from trained in the use of showed a lower level of
solids for four hours and OSBD-R until they distress.
clear fluids for two hours obtained a minimum 86% percent of patients
of 90% interobserver had no side effects.
prior to the procedure.
agreement. The incidence of vomiting,
A third observer excitement, and dysphoria
recorded evidence of was 7.8%, 4.4%, and 2%
vomiting, excitement, respectively.
dysphoria, and 8 patients developed
desaturation. ration was oxygen desaturation (SaO2
SaO2 < 95%. This was < 95%), but none developed
chosen as the patients hypoxia, airway obstruction,
were receiving an FiO2 or aspiration.
of 30±50%. Excitement 93 % of patients fulfilled the
was defined as criteria for conscious
uncontrolled laughing or sedation, and 65% had no
hysteria and dysphoria recollection . Mean recovery
was described as time was three minutes
unpleasant dreams. The
level of sedation was
rated on a scale 0±3
(table
1) by noting the
response to touch and
voice during phase 2,3.
The recovery was
recorded as the time
taken from phase 4 to
sitting up on command.