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In this write up, the aspirin tablet formulation process, the excipients of the tablet,
biopharmaceutical properties and quality control measures during the whole manufacturing
process for the 300mg aspirin tablet have been explained. Besides the availability of alternative
formulations of aspirin such as creams. Aspirin tablets are the most common formulation in use.
Aspirin tablets require regular oral administration as they are subject to pre-systemic metabolism
in the gastrointestinal tract and the liver once ingested. The direct compression method is the best
formulation for aspirin tablets due to its advantages, though there are other methods such as dry
granulation and wet granulation which can also be used. The preparation process is complex and
it entails the use of excipients in addition to the starting materials. A conventional aspirin tablet
exhibit certain biopharmaceutical properties which used to be adhered to and quality control
measures are incorporated into the preparation process to check its quality.