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ABSTRACT
The authors examine the impact of a firm’s innovation by analyzing its position in a global research-and-development
network and its orientation toward using scientific knowledge (science intensity). Drawing on organizational learning
and network theory research, they focus on the moderating role of a firm’s network position in the relationship between
the firm’s science intensity and the impact of its innovation. Data derived from the global pharmaceutical industry indi-
cate that a firm’s science intensity enhances the impact of its innovation by facilitating effective search. This relationship
is reinforced when the firm has network resources derived from an efficient network position. These results support the
idea that the impact of innovation is strengthened when internal research capability and external network resources are
combined. This study, which is conducted in a global industry network context, also enables the authors to examine the
role of international gatekeepers in bridging ties across U.S., Japanese, and European geographic boundaries.
s business becomes increasingly global, corporate Sorescu, Chandy, and Prabhu 2003; Yalcinkaya, Calan-
The purpose of this study is to examine the issue of THEORY AND HYPOTHESES
learning and innovation in the context of a global R&D Theoretical Model
alliance network to address a gap in innovation research
in the international marketing field. Two important We examine a firm’s innovation impact by drawing
questions to be addressed include the following: How from research on organizational learning and network
does a firm’s internal research enhance its innovation? theory. From a network perspective, we investigate
and How do internal R&D efforts and external R&D innovation within the boundary of the network in which
collaborations interact with each other to improve firm-level technological trajectories influence and are
innovation? influenced by other firms’ trajectories. To capture such
embeddedness in a technological network, it is impor-
In this study, we focus on the impact of a firm’s innova- tant to understand the extent to which innovations gen-
tion, paying particular attention to the firm’s position in erated by a firm are recognized and assimilated by other
a network of R&D alliances. We take a network firms. At a network level, innovations that serve as
approach in our study of innovation impact under the sources for many subsequent innovations by other firms
premise that the impact of innovation is largely a func- can be considered high-impact innovations (Rosenkopf
tion of the quality and diversity of inputs and that a and Nerkar 2001). In this study, the term “innovation
firm’s network position is associated with the quality impact” refers to the degree to which other members of
and diversity of information and resources the firm can a firm’s network have retained and built on that firm’s
acquire from the alliance network (Swaminathan and technology.
Moorman 2009).
In Figure 1, we hypothesize that a firm’s innovation
Despite the importance of the network approach in the impact increases with its science intensity—that is, its
study of learning and innovation, international market- level of efforts and inclination to use scientific knowl-
ing literature has paid little attention to the network of edge. We hypothesize that such an effect is enhanced by
R&D alliances that exists in the global marketplace network position variables such as network efficiency
(Atuahene-Gima and Murray 2007). For example, the (i.e., the extent to which the firm’s partners provide
bulk of past alliance research in the international mar- nonredundant information and resources). Our sample
keting field has taken the firm, or dyad of firms that consists of 32 U.S., 33 Japanese, and 24 European firms,
make up an alliance, as the unit of analysis, examining a multinational sample that enables us to examine the
each alliance partner’s characteristics and the type of role of international gatekeepers (Spencer 2003). We go
alliance to assess the formation, entry modes, and per- further to hypothesize that the effect of a firm’s science
formance of international collaborations such as inter- intensity on its innovation impact will be strengthened
national joint ventures (e.g., Calantone and Zhao when the firm plays the role of an international gate-
2000). However, studies in organizational theory, such keeper by absorbing knowledge from foreign firms and
as that by Powell, Koput, and Smith-Doerr (1996), have disseminating it to local firms.
added a network perspective by suggesting that a firm’s
formation of an alliance and the outcomes of that In Figure 1, the moderation model is specified according
alliance also depend on the position of the firm in the to our view that internally accumulated R&D capabili-
network of R&D alliances. Therefore, firm- and dyad- ties are the basic building blocks of innovation (Cohen
level alliance studies in international marketing can be and Levinthal 1989). We expect R&D alliances to
(+)
Science Intensity Innovation Impact
of a Firm of a Firm
(+)
complement internal R&D capabilities (Teece 1992) some firms in the industry conduct more science-driven
because each alliance partner is a potential conduit for R&D than others (Cockburn, Henderson, and Stern
valuable information and resources. Thus, being a well- 2000).
connected and significant player in an R&D alliance
network can be a crucial strategic advantage in acquir- Our prediction for the direct effect of science intensity
ing external technologies and related capabilities (Pow- on innovation impact is based on the two lines of logic
ell, Koput, and Smith-Doerr 1996). Therefore, we that underlie science-driven R&D: those of exploration
hypothesize that the diverse technologies and capabili- and focus. First, science intensity reflects a firm’s ten-
ties acquired from alliance partners contribute to a dency to engage in an explorative distant search (Cock-
firm’s internal ability and effort in producing new high- burn, Henderson, and Stern 2000). Science-based R&D
impact technology. is uncertain and costly, but the payoffs can be high when
it is successful, which is a typical pattern for an explo-
Predicting Innovation Impact from Science rative search (Atuahene-Gima 2005; March 1991).
Intensity When a firm is more science driven in its R&D, it is
more likely to appreciate the value of exploration and,
Innovation builds on knowledge gleaned from scientific consequently, be more willing to engage in exploration
studies (Gittleman and Kogut 2003). In particular, the in R&D. As such, the potential for innovative techno-
pharmaceutical industry, which is our research setting, is logical developments in R&D will be greatest when the
dependent on a complex and always-evolving scientific firm’s tendency to search for explorative technological
research base (Pisano 2006; Sorescu, Chandy, and developments is high.
Prabhu 2003), largely because of an increasing reliance
on biotechnology for its R&D activities. As a result, the Second, a firm’s science search tends to lead to more
pharmaceutical industry has become one of the most focused R&D. A firm’s focus may help it employ the
science-intensive sectors in the economy (Pisano 2006). results of scientific developments more quickly and
Although the pharmaceutical industry as a whole is sci- effectively. The capacity of a firm to take advantage of
ence driven, we still expect to find firm-level variations the results of scientific developments better and faster
in the level of reliance on science for innovation and that than competitors is a major source of competitive
Variable M SD 1 2 3 4 5 6 7 8 9 10 11
3. Firm network
efficiency .39 .48 .14** .14**
4. International
gatekeeper .14 .68 .04 .08* .22**
7. Number of R&D
alliances .52 .95 .08* .13** .64** .64** .25** .19**
8. U.S. firm dummy .36 .48 .23** .31** .08* .05 .09* –.02 .06
9. Japanese firm dummy .37 .48 –.26** –.28** –.13** –.10** –.29** –.37** –.14** –.57**
12. Firm-type dummy .59 .49 .23** .34** .12** –.04 –.31** –.05 .02 .28** –.31** .04 .12**
*p < .05.
**p < .001.
The data in Table 1 demonstrate that science intensity our sample had a higher average level of R&D expendi-
and network efficiency are positively correlated with ture than their counterparts, which may have led Euro-
innovation impact. These data indicate that both inter- pean firms to outperform U.S. and Japanese firms in
nal research efforts and external R&D collaborations terms of the number of patents acquired during our
are associated with high-impact innovation. The U.S. research period. Table 2 also shows that, in general, U.S.
and European firm dummies are positively correlated firms had the highest level of innovation impact, though
with innovation impact, whereas the Japanese firm they produced a smaller number of patents than Euro-
dummy is negatively correlated with innovation impact. pean firms. This result may be due to the difference in
However, the patterns and trends across the three science intensity between U.S. and European firms. We
regions (see Figure 2) corroborate that there is a positive broke the firm types into dedicated pharmaceutical
association between science intensity and innovation firms and diversified firms and found that both U.S. and
impact. European groups were dominated by dedicated pharma-
ceutical firms, whereas the Japanese group was domi-
Table 2 presents the descriptive statistics of the U.S., nated by diversified firms. Firm-type data indicate that
European, and Japanese firms. On average, U.S. firms the difference in innovation impact across the three
employed the highest level (4.03) of science intensity, groups is partially affected by the different business
followed by European firms (2.19) and Japanese firms portfolio profiles of these groups.
(1.02). Network position variables for U.S. and Euro-
pean firms revealed that these firms used external R&D Table 3 shows the results for the hypotheses tests.
collaboration more efficiently than Japanese firms. The Model 1, a baseline model consisting only of control
data in Table 2 also reveal that the European firms in variables, indicates that the Japanese firm dummy
1.4 6
1.2
8
1
4
.8
3
.6
2
.4
1
.2
0 0
88 89 90 91 92 93 94
Year
Innovation impact of U.S. firms Innovation impact of European firms
Innovation impact of Japanese firms Science intensity of U.S. firms
Science intensity of European firms Science intensity of Japanese firms
(b = –.517, p < .001) and the firm-type dummy (b = ciency is positive and significant (b = .156, p < .001),
.212, p < .05) have significant effects on innovation and Model 6 shows that the interaction term between
impact. Model 2 shows a significant, positive associa- science intensity and international gatekeeper also is
tion between science intensity and innovation impact positive and significant (b = .064, p < .05). We included
(b = .252, p < .001). The coefficient of science intensity the two interaction terms together in Model 8 and
remains positive and significant regardless of the model found that only the interaction term between science
specification. These results provide strong support for intensity and firm network efficiency remained positive
H1. and significant (b = .149, p < .001). Taken together,
these results support H2a but only weakly support H2b.
Before testing H2, we included network position
variables in the model to control for the main effects of Figure 3 graphically shows the interaction, for which we
these variables. Though not our main focus of interest, relied on Jaccard, Turrisi, and Wan’s (1990) procedure.
the results are presented in Models 3 and 5. Firm net- First, we divided the sample into two groups based on
work efficiency has a significant and positive effect on the median value of firm network efficiency. We further
innovation impact, whereas the effect of international divided each of the two groups (i.e., lower and higher
gatekeeper is insignificant. network efficiency groups) into lower and higher science
intensity groups in terms of the median value of science
To examine H2, we also included the interaction term intensity. Second, we calculated the mean values for
between science intensity and each of the two network each of the four resulting groups and used the results
position variables. Model 4 indicates that the inter- from Model 8 (Table 3) to develop plots for the moder-
action term between science intensity and network effi- ating effect of firm network efficiency. As Figure 3
Network Positions
Firm Firm Number Science Firm Network International R&D Number of Innovation
Nationality Type of Firms Intensity Efficiency Gatekeeper Expenditurec Patents Impact
U.S. firms Dedicated 25 (78%) 4.786a .483 .158 400.4 53.5 1.083
pharmaceutical (5.866)b (.496) (.503) (323.1) (47.1) (.747)
shows, the positive relationship between science inten- academics and practitioners who work to understand
sity and innovation impact is more pronounced in the durable and sustained superior performance (Sorescu,
higher network efficiency group than in the lower net- Chandy, and Prabhu 2003).
work efficiency group. This pattern is consistent with
our argument in H2a. Therefore, the interaction graph In this study, we observed that a firm’s science intensity
presented in Figure 3 provides additional support for has a positive direct effect on the impact of its innova-
H2a. tion. This finding is consistent with Fleming and Soren-
son’s (2004) observation that utilization of scientific
knowledge in patented inventions generates more inno-
DISCUSSION AND CONCLUSION vation impact by facilitating effective search. Further-
more, our data suggest the critical role of science inten-
High-impact innovations represent rare, valuable, and sity in integrating scientific research (R) with
potentially inimitable sources of competitive advantage technological development (D), though previous studies
(Rosenkopf and Nerkar 2001). Understanding how have suggested that the social structures of the science
firms create breakthrough innovations and sustain their world and the technology world are distinct (Murray
preeminence in an industry is of fundamental concern to 2002). Science is characterized by publication and sup-
Independent Variables Model 1 Model 2 Model 3 Model 4 Model 5 Model 6 Model 7 Model 8
Number of patents –.136† –.075 –.075 –.070 –.073 –.076 –.077 –.072
(.072) (.071) (.071) (.070) (.071) (.071) (.071) (.070)
R&D expenditure .030 .018 .013 .025 .015 .018 .017 .027
(.070) (.068) (.068) (.067) (.068) (.068) (.068) (.067)
Number of R&D alliances .058 .031 –.037 –.043 .041 .039 –.057 –.056
(.042) (.041) (.050) (.049) (.052) (.052) (.066) (.064)
Japanese firm dummy –.517*** –.337** –.335** –.353** –.337** –.345** –.335** –.358**
(.130) (.130) (.130) (.128) (.130) (.130) (.129) (.128)
European firm dummy –.206† –.099 –.092 –.115 –.098 –.097 –.094 –.114
(.106) (.105) (.104) (.103) (.105) (.104) (.104) (.103)
Firm–type dummy .212* .126 .102 .126 .124 .135 .103 .127
(.096) (.095) (.095) (.094) (.095) (.094) (.095) (.094)
Regional network density .124 .118 .116 .107 .119 .127 .113 .106
(.106) (.103) (.103) (.101) (.103) (.103) (.103) (.102)
Year 1989 dummy –.254 –.304† –.322* –.304† –.306† –.319* –.319* –.305†
(.162) (.158) (.157) (.155) (.158) (.157) (.157) (.156)
Year 1990 dummy –.177 –.218 –.239 –.199 –.222 –.220 –.234 –.197
(.166) (.161) (.161) (.159) (.162) (.161) (.161) (.159)
Year 1991 dummy –.318 –.366† –.410* –.349† –.371† –.369† –.405* –.347†
(.196) (.191) (.191) (.189) (.193) (.191) (.191) (.189)
Year 1992 dummy –.251 –.339** –.349* –.337* –.340* –.335* –.348* –.336*
(.154) (.150) (.149) (.147) (.150) (.149) (.149) (.147)
Year 1993 dummy –.109 –.208 –.218 –.168 –.215 –.210 –.207 –.162
(.226) (.220) (.219) (.217) (.221) (.221) (.220) (.218)
Year 1994 dummy –.451 –.534† –.575† –.504 –.539† –.531† –.567† –.501
(.330) (.321) (.320) (.317) (.321) (.320) (.320) (.317)
Independent Variables Model 1 Model 2 Model 3 Model 4 Model 5 Model 6 Model 7 Model 8
Wald chi-square 88.54*** 130.71*** 137.65*** 157.17*** 130.81*** 135.98*** 137.92*** 157.42***
†p < .10.
*p < .05.
**p < .01.
***p < .001.
Notes: This table reports standardized regression coefficients, with standard errors in parentheses.
ported by a priority-based reward system, which is in point to the conflicting logic behind innovation rate and
contrast to the world of technology, in which ideas are innovation impact. There is an inherent tension between
produced for economic ends and encoded in patents exploitation and exploration in innovation processes
to facilitate appropriability. Given the two distinctive (March 1991): Exploitation improves innovation effi-
communities of science and technology, Gittelman ciency, whereas exploration is required to produce new
and Kogut (2003) emphasize the bridging role of technologies of high quality and impact (Atuahene-
inventors in a firm as a critical function in the firm’s Gima 2005). Thus, firms must undergo the paradoxical
ability to materialize scientific research into valuable strategic task of balancing between exploitative and
technologies. explorative innovation strategies (He and Wong 2004).
This study measured science intensity by the extent to Our finding that science intensity interacts with R&D
which a firm cites scientific findings in its patents. By alliance network variables supports the complementary
explicitly tying scientific publishing and patenting roles of internal and external R&D activities in innova-
together, this measure incorporates the degree to which tion. In particular, the data support our network moder-
a firm encourages inventors who are directly involved in ation argument that the effect of science intensity on
the firm’s technology development to participate in the innovation impact is stronger when a firm’s science
scientific community. We conclude that in circumstances intensity is combined with its network resources (i.e.,
in which scientific research is tightly linked to tech- the quality and diversity of information and resources
nology developments, how firms access and practice sci- derived from the firm’s position in the network of R&D
ence plays a critical role in the production of valuable alliances). As Table 3 shows, the direct effect of network
technologies. variables is, by and large, weak or nonexistent; however,
we estimated all the interaction terms as positive and
The data in Table 2 indicate that U.S. firms score rela- significant. Figure 3 also shows that the effect of science
tively high with regard to science intensity and innova- intensity on innovation impact is more pronounced in
tion impact, whereas European firms score high in both the high than the low network efficiency group, provid-
R&D expenditure and number of patents. Therefore, it ing support for our argument on firm heterogeneity in
seems that R&D expenditure is associated with the network resources. Not all firms can enhance their inno-
number of patents produced, though science intensity vation impact by configuring their portfolios of alliances
itself is associated with innovation impact. These results into efficient networks.
Innovation Impact
2.339
Firm network efficiency: high
1.276
Firm network efficiency: low
.438
.187
Science Industry
Low High
When the two network variables (firm network effi- licensing, joint R&D contracts, and joint R&D
ciency and international gatekeeper) enter an equation ventures. However, there is a substantial difference
simultaneously, only the significance of the efficiency between R&D alliances designed mainly to effect an
variable survives, and that representing the international exchange of existing technologies and those designed to
gatekeeper variable disappears. These findings suggest generate new technologies. In addition, R&D alliances
that leveraging knowledge globally, rather than region- provide access to external complementary technologies,
ally, is more important in producing high-impact inno- facilitating the exploitation of existing technologies
vation because the efficiency variable measures the con- (Teece 1992), and offer a way to explore new technolo-
cept of network range in the global industry context, gies jointly with partners (Powell et al. 1996).
whereas the international gatekeeper variable measures Because the exploitative licensing mode is different
the same concept in the domestic-foreign context, with from explorative joint R&D modes, for an
reference to the United States, Japan, and Europe as ex post check, we eliminated licensing from our sample
regional groups. This finding agrees with extant inter- and reran the analysis but found no significant devia-
national marketing research on the globalization of tions from our results. However, distinguishing a net-
R&D activities (Murray and Chao 2005; Özsomer and work of explorative R&D alliances from that of
Gençtürk 2003). In an era of globalization, configuring exploitative ones remains an area for further research,
and managing a portfolio of alliances worldwide has perhaps with an enriched database on R&D collabora-
become more salient and important. tions. Second, given that cross-country comparisons in
patent indicators are useful areas for study, further
Although this study directly examines the impact of research should be conducted with multicountry patent
innovation in a global industry network context, it has data. Third, although we believe our findings can be
a few limitations. First, notwithstanding the aforemen- generally applicable to other science-intensive indus-
tioned merits of network analysis, with its primary tries in which integrating scientific research with tech-
focus on the network as a whole, network analysis nology development is important, we admit that such a
does not differentiate between the types and modes claim is actually an empirical question. Therefore, we
of alliances within the domain of a R&D network. also suggest that our findings be validated with further
Broadly defined, R&D alliances include technology research in other industrial settings.
Greene, William H. (2003), Econometric Analysis. Upper Sad- Powell, Walter W., Kenneth W. Koput, and Laurel Smith-Doerr
dle River, NJ: Prentice Hall. (1996), “Interorganizational Collaboration and the Locus of
Singh, Jasjit (2008), “Distributed R&D, Cross-Regional Knowl- Changsu Kim is Associate Professor of International
edge Integration and Quality of Innovative Output,” Research Business at Sogang University, Korea. He earned his
Policy, 37 (1), 77–96. doctoral degree at Rutgers University. His research
Sorescu, Alina B., Rajesh K. Chandy, and Jaideep C. Prabhu
interests include cross-border alliances, learning and
(2003), “Sources and Financial Consequences of Radical innovation, and foreign direct investment from emerg-
Innovation: Insights from Pharmaceuticals,” Journal of Mar- ing markets.
keting, 67 (October), 82–102.
Spencer, Jennifer (2003), “Global Gatekeeping, Representation, Jong-Hun Park is Professor of Strategic Management at
and Network Structure: A Longitudinal Analysis of Regional Sogang University, Korea. He obtained his doctoral
and Global Knowledge-Diffusion Networks,” Journal of
degree from the Sauder School of Business, University of
International Business Studies, 34 (5), 428–42.
British Columbia. His research interests center on strate-
Swaminathan, Vanitha and Christine Moorman (2009), “Mar- gic leadership, strategic alliance, and innovation
keting Alliances, Firm Networks, and Firm Value Creation,” management.
Journal of Marketing, 73 (September), 52–69.