02 Basicsin 43 dermatology I! a. Diascopy = The glass slide is pressed on lesions Cvitropression ) exythema Purpura = Pblood in vessel = Extravasation of 26C. = Blanching response = Stain on blood vessel wall = Non-blanching response ~ Polpable purpura \ ‘Small vessel vasculitis + Diascopy : uses > Lupus vulgaris (cutaneous TS ) + Glass slide is pressed ( ‘ Apple jelly nodules Dermatologic investigat 00:92:54 = woods light = wavelength * 360-364 nm = woods lamp fiter ! > Nickel oxide (9%) > Barium silicate Dermatology + v2.0 * Marrow 4.0 « 202014 Dermatology 02 woods lamp uses # 1. Infections = Fungal and corynebacterial A. Tinea capitis, = mierosporum -> Blue green = Trichophyton schoenieini > dull blue 8. Pityriasis versicolor ~ Superficial fungal infection = malassesia, globosa >? Surfur = Yellow Suoreseence erythrasma, = Produced by corynebacterium minutissimum = Coral red Suoreseence C coproporphyrin = i 4. Pigmentary disease C1) Ash leat macule (Tuberous sclerosis ) Ca) vitiigo (a) melasma 3, miscellaneous 8. Porphyria cutanea tarda ~ Pik (urine) = Enzyme defect : ueoD ‘ uroporphyrinogen decarboxyiase 8. Congenital erythropoietic porphyria - 8/6 / A Gunther's disease, ~ Teeth : Red ( erythrodontia ) Dermatology + v2.0 * Marrow 4.0 + 2020Dermatologic diagnosis - LAB investigations 00:40:10 1. Koh mount = Sample + Skin / Hair / Noil 4 oh Dissolve Keratinocytes + Koh mount uses A. Dermatophytosis 6. Pityriasis versicolor C. Chromoblastomycosis C Subcutaneous mycosis J = Branching retractie - short hyphae. = Grown coloured hyphae, (spaghetti + bodies (sclerotic / round spores, media / muriforrn / Crmeatinalt) Copper penny bodies ) = Spaghetti and meattoalt appearance a. Tzanek smear = Cytodiagnostie test NG = vesicle > deroot > base of vesicle scraped = Stain: eiemsa, * Tzanek smear uses A. Pemphigus group 8 Herpes - |, a, 3 infection = Acantholytic cetis / = Multinucieated Tanck cells, giant celis Dermatology + v2.0 * Marrow 4.0 © 2020 0: Basics in dermatology I! 1516 Dermatology 02 * Basics in therapeutics, Cryotherapy, = Liquid n, (196° ¢) ~ For treatment of warts (palo / plantar), genital warts (pregnancy) 8 6. Phototherapy = used in# 1. Psoriasis a. Atopic dermatitis 2. vitlign = Commonly used NB - Uv (ii a om) PuvA: Psoralen + uve Cphotosensitiser ) Dermatology + 2.0 * Marrow 4.0 + 2020