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Explain why cancer is regarded as abnormal cellular function

Most normal cells remain in a non-proliferative state unless they are stimulated to divide to
replace lost cells. Abnormal regulation of the cell cycle can lead to the over proliferation of cells
and an accumulation of abnormal cell numbers. Cancer cells arise from one cell that becomes
damaged, and when divided, the damage is passed on to the daughter cell and again to the
granddaughter cells and so on. Rather than responding appropriately to the signals that control
normal cell behavior, cancer cells grow and divide in an uncontrolled manner, invading normal
tissues and organs and eventually spreading throughout the body. The generalized loss of
growth control exhibited by cancer cells is the net result of accumulated abnormalities in
multiple cell regulatory systems and is reflected in several aspects of cell behavior that
distinguish cancer cells from their normal counterparts
Describe the occurrence of genetic diseases
A genetic disorder is a disease caused in whole or in part by a change in the DNA sequence
away from the normal sequence. Genetic disorders can be caused by a mutation in one gene
(monogenic disorder), by mutations in multiple genes (multifactorial inheritance disorder), by a
combination of gene mutations and environmental factors, or by damage to chromosomes
(changes in the number or structure of entire chromosomes, the structures that carry genes).
Reference:

Cooper, G. M. (1970, January 1). The Development and Causes of Cancer. Retrieved from
https://www.ncbi.nlm.nih.gov/books/NBK9963/

Genetic Disorders. (n.d.). Retrieved from https://www.genome.gov/For-Patients-and-Families/Genetic-


Disorders

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