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Isopropyl Rubbing Alcohol
» Isopropyl Rubbing Alcohol contains not less than 68.0 percent and not more
than 72.0 percent of isopropyl alcohol, by volume, the remainder consisting of
water, with or without suitable stabilizers, perfume oils, and color additives
certified by the FDA for use in drugs.
Packaging and storage— Preserve in tight containers, remote from heat.
Labeling— Label it to indicate that it is flammable.
Acidity— Transfer 50 mL to a suitable flask, and add about 75 mL of carbon dioxide-free water.
Titrate potentiometrically to a pH of 8.5: not more than 1.0 mL of 0.020 N sodium hydroxide is
required for neutralization.
Assay— Transfer 50.0 mL of Isopropyl Rubbing Alcohol to a 250-mL distilling flask, and add 100
mL of water. Arrange the flask for distillation, distil, and collect 95 mL of distillate in a 100-mL
volumetric flask. Dilute to volume with water, mix, and determine the specific gravity of the distillate
at 25 (see Specific Gravity 841 ). The specific gravity is between 0.955 and 0.950,
corresponding to between 68.0% and 72.0% of isopropyl alcohol in the specimen taken.
Expert Committee : (MDAA05) Monograph Development-Antivirals and Antimicrobials
USP30–NF25 Page 2415
Phone Number : 1-301-816-8394