Professional Documents
Culture Documents
Gap in risk communication (e.g. HKAPI maximum limit far above WHO maximum
limit
Risk communication
- Hedley Index for air pollution
Calculate pain (excess number of adverse health outcomes per yea
Illness cognition: A patient’s own common sense beliefs about their illness, serves as
a framework or schema for coping with and understanding their illness, and telling
them what to look out for if they are becoming ill
Five dimensions of illness cognition
- Identity
- Perceived cause of illness
- Timeline
- Consequence
- Curability and controllability
Stages of illness
- Symptom experience
- Assumption of sick role
- Medical care contact
- Dependent-patient role
- Recovery and rehabilitation
Health behaviour
Vaccine effectiveness
Herd immunity: vaccinating an individual indirectly reduces the risk of infection of his
contacts, his contacts’ contacts, and so on, i.e. the whole population
Medicalisation of devision
- The process of defining an increasing number of life’s problems (non-medical) as
medical problems
Causality
- Derministic causality: necessary cause, sufficient cause, sufficient-component
cause (no one cause is sufficient)
- Probabilistic causation
- Prediposing factors: prepare, sensitize, condition or otherwise create a situation
that the host tends to react in a specific fashion to a disease agent.
- Precipitating factors: associated with definitive onset, usually necessary
- Enabling factors: facilitate the manifestation
- Reinforcing factors: perpetuate or aggravate the presence
- Counterfactual definition
Henle-Koch’s postulates
- Agent present in every case of the disease
- Agetn must not be found in cases of other disease
- Once isolated, agent must be capable of reproducing the disease in experimental
animals
- Agent must be recoverd form the experimental disease produced
Mill’s Canon
- Method of agreement
- Method of disagreemtn
- Joint method
- Method of concomitant variation
- Method of residues
Health economics
Cost-effectively analysis
- Cost: medical cost, productivity loss
- Outcome:
- QALY: measures equivalent healthy years lived (0=comparable to death)
- DALY: measure loss of health (1=death)
- Mortality rate: the number of deaths in a population per 1000 individuals
per year
- Crude death rate: the number of deaths per year per 1000 population at
risk of dying in the middle of the year
- Standardized rates (age/sex standardized)
-
- Incremental cost-effectiveness ratio (ICER): difference in cost/difference in
outcome
Measurement of morbidity
- Health care utilization data
- Surveillance data
- Registration of disease
- Population-based health information
- Trade-off between coverage, specificity and timeliness
- CART: completeness, accuracy, Relevance, timeliness
Gut microbiota
- manipulated by probiotics, prebiotics, antibiotics, fecal transplant, weight loss
- Types and location
- Upper GI: acidic, oropharynx,
- Small intestines: short transit time, bile, facultative anaerobes
- Large intestines: slow flow rate, neutral to mildly acidic pH, low oxygen,
obligatea anaerobes
- Function
- Help digest
- Produce nutrients (biotin, vit K)
- Trains immune system
- Stops growth of pathogenic bacteria (competition, fermentation makes
colon more acidic)
- Modifies drugs
- Potential chronic disease relevant: obesity, diabetes, mental health, hormone
levels, colorectal cancer, infections, malnutrition