Professional Documents
Culture Documents
EVALUA
NO OBJECTIVE LEARNING BOARD AIDS TION
ACTIVITY
1 ½ State the Introduction
min introduction Tuberculosis is an infectious disease that primarily
affects the lungs parenchyma. It is also may be
transmitted to other part of the body including the
kidneys, bones & lymph nodes etc. the primary
infectious agent mycobacterium tuberculosis is an
acid fast aerobic that grows slowly & is sensitive to
heat & ultraviolate light.
Definition:-
It is an infectious disease caused by mycobacterium
tuberculosis & lungs is the common site of disease.
Base :-
This is concave & semilunar in shape & rice on the
thoracic surface on the diaphragm.
Costal surface :-
The surface is convex & lies against the costal
cartilages, the ribs & the intercostals muscles.
Medial surface :-
This surface is concave & has a roughly triangular
shaped area, called hilum at the level of the 5th, 6th &
7th thoracic vertebrae.
Associated structure of lungs :-
The area between the lungs in the mediastinum. It is
also occupied by the heart, great vessels, trachea,
right & left bronchi oesophagus, lymph nodes, lymph
vessels & nerve.
The right lungs is divided into three
distinct lobes superior, meddle & inferior. The left
lung is smaller because the heart occupies space left
of the midline. If is divided into two lobes superior &
inferior.
Etiology:-
The risk factor of tuberculosis [TB] are given below :
Inhaled the air which is contaminated with
mycobacterium tuberculi
Close contacted with an infected person .
Living in crowd and powerty.
Occupation
Malnutrition
Pathophysiology :
A succeptible person inhales micro bacterium bacilii
and becomes infected. The bacteria are transmitted
through the airway to the alveoli, where they are
deposited and began to multiply. The bavilli also are
transpposrted via lymph system and blood streem to
other parts of the body and other areas of the lungs
the bodies immune reaction phagocyte ingulf many of
the bacteria and TB – specific lymphocytes
destroy.the bacilli and normal tissue reaction result in
the accumulation of exudates in the alveoli causing
bronchopneumonia . the initaial infection usullay
occurs 2-10 weaks after exposure .
After initial exposure and infection the person may
develop active disease because of a compromised or
in adequate system response .
Diagnostic findings ;
1. A complete history
2. Physical examination
3. Chest x ray
4. Acid fast basillus smear
5. Sputum culture
6. Montus test
7. Polymerase chain reaction(PCR).
8. according to revised national tuberculosis
control program to find out :
ask the patient if he have had cough for 3
weeks or more .
for the patient with cough 3 week or
more ensure that 3 sputum
examinations(spot-morning –spot).are
done in a designated microscopy center.
Management :
pulmonary TB is treated :primarily with
chemotherapeutic agent for 6-12 months .
Several types of drugs resistancy must be
considered when planning effective therapy.
1. Primary drug resistance: resistance to one of
the first line anti tuberculosis agent In a person
who has not had previous treatment.
2. Secondary or acquired drug resistance:
resistance to one or more anti tuberculosis
agent in a patient under going therapy.
3. Multi ddrug resistance :resistency to two agents
isoniazid and rifampcin the population at
highest risk for multi drug resistance are those
who are HIV positive, institutionised or home
less.