XII.

DRUG STUDY
Drug Name Mechanism Indications Contraindications Adverse Effects Nursing Responsibilities RATIONALE
of Action
 Generic Name: -Bacterial -Treatment -Contraindicated to CNS: Lethargy - Assess for allergies to To prevent any
Ampicillin action for infections patients with allergies hallucinations, penicillin cephalosporin’s problems and errors,
 Brand Name: against caused by to penicillin’s, seizures. or other allergens and about the patients
Ampicin sensitive susceptible cephalosporin’s, or GI: Glossitis renal disorders. condition.
 Classification: organism strains of H other allergens stomatitis, gastritis,
*Antibiotic influenza. soremouth furry
*Penicillin -Inhibits tongue black “Hairy” -Check IV site carefully -To assure that the
 PREGNANCY synthesis of Vomiting, Diarrhea, for signs of thrombosis drug is not
RISK bacterial cell Abdominal or drug reaction. interrupted and
CATEGORY: “B” wall, causing pain,Bloody, direct on the system
 Dosage: cell death. Diarrhea,Enterocolitis, -Teach SO to report affected during the
500mg Pseudomembranous patients pain or administration.
 Route: Colitis, nonspecific discomfort at sites,
IVTT hepatitis. Unusual bleeding or -To know If there are
 Frequency: bruising mouth sores unsual discomfort
*q 6 hrs ANST (-) Hypersensitivity: rash hives fever itching about the patient
Rash, fever, wheezing, severe diarrhea difficulty condition.
Anaphylaxis. breathing.
Local: Pain Phlebitis
thrombosis at - Observed 12r’s of -To ensure the
injection medication patients safety and
site(parental) administration. prevent medical
Others: Super errors.
infections –oral and
rectal moniliasis.
 Drug Name Mechanism Indications Contraindication Adverse Effects Nursing Responsibilities Rationale
of Action s
 Gentamycin -Inhibits -Serious infection -Contraindicated  EENT: -Assess for infections (vital To note if thier are
(Gentamycin) protein caused by with allergy to ototoxicity signs, wound appearance, changes in patient
 Classification: synthesis in susceptible any vestibular sputum,urine,stool,WBC) condition or arises of
Anti- Infectives bacteria at strains of aminoglycosides. and at beginning of and WBC count that
 Pregnancy Risk level of 30s pseudomonas -Use cautiously cochlear. throughout therapy. indicates infection.
Category: ribosome aeruginosa with renal or  GU:
“B” bactericidal proleus species, hepatic disease, Nephrotoxic
 Dose: action. Escherichia coli, sulfite sensitivity ity
240mg klebsiella preexisting  F&E:
 Route: enterobacter- hearing loss Hypomagne
IVTT serratia species, active infections saemia
 Frequency: citobacter, and mycobacterial  MS: Muscle -Monitor intake and output -To identify problem
staphylococcus infections paralysis and daily weight assess areas promptly for
 OD ANST (-)
species. (ophthalmic (High hydration status and renal treatment and
-serious infection preparations) Parenteral function. prevention.
when causative myasthenia Doses)
organisms are gravis  Misc:
not known( often parkinsonism Hypersensiti
in conjunction infant botulism vity -Assess skin and inform -Helps maintain the
with penicillin or burn patient reactions. health care professional If balance of the body
cephalosporin’s. lactation skin irritation develops or fluids.
pregnancy. infections worsens.

-Always advice the patient -To ensure the

about the importance of patients safety and
drinking plenty of prevent medical
liquids/water. errors.
 Drug Name Mechanism of Indications Contraindications Adverse Effects Nursing Responsibilities Rationale
Action

 Generic name: -Direct acting -Bacterial -Hypersensitivity -Fever flushing -Monitor liver function test -To ensure the patients
Metronidazole trichomonacid infections caused -Pregnancy, 1ST abdominal results carefully in elderly safety and prevent
 Brand name: e by anaerobic trimester. cramping or patients. medical errors.
Zalvos And amebicide microorganism. pain nausea
 Classification: that works at and vomiting -instruct patient to take -To avoid fetal alcohol
Amebicides both intestinal constipation oral form with food to spectrum disorders.
 Dose: and dry mouth minimize GI upset but tell
500mg extraintestinal metallic taste the patient/s to extend
 PREGNANCY sites. Its darkened urine. release tablets at least
RISK thought to 1hour before or after 2
CATEGORY: enter the cells hours after meals.
“B” of
 Route: microorganism -tell the patient to avoid -To inform the patient
IV that contain alcohol. about the normal
 Frequency: nitroreductase, -tell the patient that she adverse effect of the
q 8 hrs unstable may experience a metallic medication.
compounds are taste and dark or red brown
then formed urine.
that bind to
DNA and
inhibit
synthesis
causing cell
death.

Drug Name Mechanism of Indications Contraindication Adverse Effects Nursing Responsibilities Rationale
 Action
 Generic Name: -Hinders Amebic Hypersensitivity Seizures, dizziness -Assess patient infection. -To prevent any
Metronidazole growth of hepatic Hypersensitivity headache, -Give drug with meals to problems and errors,
 Brand Name: selected abscess, to parabens. abdominal pain, minimize GI distress. about the patients
Flagyl organisms, intestinal First trimester of anorexia nausea, condition.
 Classification: including most amebiasis, pregnancy. and vomiting
Anti-bacterial Anti anaerobic Trichonomiasis diarrhea, dry
protozoal bacteria and Bacterial mouth glossitis,
 Dosage: protozoa. Infection, rashes skin
500mg TAB caused by irritation. -Tablets may be crushed -To assure that the drug
 PREGNANCY anaerobic for patient/s with difficult is not interrupted and
CATEGROY: microorganism swallowing. direct on the system
“B” Pelvic affected during the
 Route: inflammatory administration.
PO disease.
 Frequency: -Tell patient that metallic -To know If there are
1 TAB q 8 hrs taste and dark or red unsual discomfort about
brown urine may occur. the patient condition.

-Instruct patient to -To ensure the patients

complete full course of safety and prevent
therapy. medical errors.