Professional Documents
Culture Documents
Hpaa057 PDF
Hpaa057 PDF
The world is currently suffering from COVID-19 patients are hypertensive is formation of angiotensin II in the case
the outbreak of a pandemic caused by not entirely surprising nor does it nec- of ACE inhibitors, or by antagonizing
com/apps/opsdashboard/index.html#/ 6. Wan Y, Shang J, Graham R, Baric RS, Li F. 10. Imai Y, Kuba K, Rao S, Huan Y, Guo F, Guan B,
bda7594740fd402994. Accessed 30 March 2020. Receptor recognition by the novel corona- Yang P, Sarao R, Wada T, Leong-Poi H,
3. Zhou F, Yu T, Du R, Fan G, Liu Y, Liu Z, virus from Wuhan: an analysis based on Crackower MA, Fukamizu A, Hui CC, Hein L,
Xiang J, Wang Y, Song B, Gu X, Guan L, Wei Y, decade-long structural studies of SARS coro- Uhlig S, Slutsky AS, Jiang C, Penninger JM.
Li H, Wu X, Xu J, Tu S, Zhang Y, Chen H, navirus. J Virol 2020; 94:e00127-20. Angiotensin-converting enzyme 2 protects
Cao B. Clinical features of patients infected 7. Hoffmann M, Kleine-Weber H, Schroeder S, from severe acute lung failure. Nature 2005;
with 2019 novel coronavirus in Wuhan, Krüger N, Herrler T, Erichsen S, Schiergens TS, 436:112–116.
China. Lancet 2020; 395:497–506. Herrler G, Wu N-H, Nitsche A, Müller MA, 11. Phadke M, Saunik S. Rapid response: use
4. Wu C, Chen X, Cai Y, Xia J, Zhou X, Xu S, Drosten C, Pöhlmann S. SARS-CoV-2 cell of angiotensin receptor blockers such as
Huang H, Zhang L, Zhou X, Du C, Zhang Y, entry depends on ACE2 and TMPRSS2 and is Telmisartan, Losartsan in nCoV Wuhan
Song J, Wang S, Chao Y, Yang Z, Xu J, Zhou X, blocked by a clinically proven protease inhib- Corona Virus infections—novel mode
Chen D, Xiong W, Xu L, Zhou F, Jiang J, Bai C, itor. Cell 2020; 181:1–10. of treatment. Response to the emerging