HUMAN GENOME PROJECT

- Decoding and sequencing

A 13 YEAR
the human genome ( 1990-
2003) EFFORT
DR. JAMES WATSON An international research
with collaboration of
- Molecular Biologist scientists from 6 countries
- First Director of HGP

Hierarchal shotgun sequencing• Manual sequencing • Harnessing

data• Large scale sequencing using computer• Sharing data•
Cultural change on data sharing• Information gathering to be used in
future• Addressing societal concerns
Offered information on how the body works - Provided details on how diseases
generate - If and how drugs work - Transformed healthcare - Genetic
information - Proved genes have different functions - 3.2 billion A C G T bases
make up the human genome - Some genes come from bacteria - Provided
detailed information about chromosomes - HGP cost 3 billion dollars
ELSI PROGRAM’s FOCUS ON GENOMIC RESEARCH
ETHICAL, LEGAL AND SOCIAL 1. Discretion and fairness of genetic information (e.g genetic discrimination in employment)
Reference:
IMPLICATIONS (ELSI) PROGRAM
2. The incorporation of new genetic technologies (e.g genetic testing in medicine practice)
- Created in 1990 to address
3. Ethical Issues on the design and conduct of genetic research (e.g Informed consent)
genomic research that affects
the society and its people 4. The knowledge of professionals about genetics and complex issues resulted from genetic
research
Help Me Understand Genetics - Genetics Home Reference - NIH. (n.d.). Retrieved April 04, 2020, from
https://ghr.nlm.nih.gov/primer

DNA Sequencing. (n.d.). Retrieved April 04, 2020, from https://www.genome.gov/dna-day/15-ways/dna-sequencing