BIOSCIENCE REPORTS
ACCEPTED MANUSCRIPT

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Cite as Bioscience Reports (2016) DOI: 10.1042/BSR20160149

Copyright 2016 The Author(s).

This is an Accepted Manuscript; not the final Version of Record. You are encouraged to use the final Version of Record that, when
published, will replace this manuscript and be freely available under a Creative Commons licence.
All other rights reserved.
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