COURSE CODE:                                  PHA 326

COURSE TITTLE:                                 PHARMACOLOGY - QUIZ

INSTRUCTOR:                                    MRS M MATOME

DURATION:                                         9 to 11 am

DATE:                                                    19 June 2020

TOTAL MARKS:                                  10 Marks                   

Name:Mompati Letsweletse Id:201100183

1) Advice on how to handle the situation for hypertensive patients and why  (4)
Advice the prescriber to consider using the following drugs as an alternative:
1) Telmisartan + Amlodipine (80+5) mg tablet
2) Telmisartan + Amlodipine (80+10) mg tablet
3) Enalapril maleate 20 mg tablet
4) Enalapril maleate 5 mg tablet
5) Hydrochlorthiazide 12.5mg
Reasons: For hypertensive patients who have been on ARBS and a thiazide consider
switching them an ace inhibitor and a thiazide if they are intolerant suggest Telmisartan +
Amlodipine
Ace inhibitors are considered because safe and effective for treatment of both hypertension
and heart failure. They reduce mortality in patients with heart failure and reduce
cardiovascular outcomes.Acei are suggested because they demonstrates comparable clinical
outcomes with Arbs

2) Advice on how to handle the situation for patient with heart failure and why (4)

1) Enalapril maleate 20 mg tablet

2) Enalapril maleate 5 mg tablet
3) Hydralazine 10 mg tablet
4) Hydralazine 50 mg tablet
5) Isosorbidedinitrate 10 mg tablet
6) Hydrochlorthiazide 12.5mg

Reasons: For heart failure patients who have been on ARBs switch them to Ace inhibitor if
intolerant suggest hydralazine and a nitrate. For patients who have been on ARB/Thiazide
suggest ACE and thiazide.
How are you going to implement the above advice?  (2)
Talk to the prescriber about the drugs that are available and provide evidence in terms of the
pharmacokinetics, pharmacodynamics ,contraindications drugs-drug interaction for each and
every medicine to be introduced .For every switching the following information from the
patient should be changed
Upon receiving a prescription from the doctor Pharmacists must collect and/or generate the
following information about the patient: subjective and objective information about the
patient's general health and activity status, past medical history (i.e. the diseases and
conditions they have had), include family medical history, medication history, social history,
diet and exercise history, history of present illness. The sources of the aforementioned
information can be collected from Patients’ interview, medical charts and reports,
Pharmacist-conducted health/physical assessment, the patient's family or caregiver, insurer,
and other healthcare providers e.g. prescribers. After going through the process the patient
can now be switched to a new drug with continuous monitoring