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a.

How to Prepare (Including Formula)


b. Indications along with ideal Concentration for Use
c. Storage and Specific Container to be Used
d. Beyond Use Date
e. Information that Should be present on the label

70% Ethyl Alcohol

a. A quick means of making a known concentration of ethanol from a stronger


concentration without having to do any calculations is to take the volume
equivalent to the concentration wanted and add water to the volume
equivalent to the stronger concentration used. For example, to make 70%
ethanol from 95% ethanol, take 70 mL of 95% ethanol and add enough water
to bring the volume to 95 mL. You will then have 95 mL of 70% ethanol. This
works for any dilution and all that is required is a large enough graduated
cylinder.
Lugol’s Solution

a. Dissolve KI in about 20-30 ml of distilled water. Add iodine and heat gently with constant mixing
until iodine is dissolved. Dilute to 100 ml with distilled water. Store in amber glass-stoppered
bottle in the dark.

b. LUGOL’s is a topical antiseptic. Strong Iodine Solution is a germicide and fungicide. LUGOL’s is
preservative-free.
c. Keep tightly closed. Protect from light (Place in amber bottle or other light resistant containers).
DO NOT use if seal has been broken. Store at controlled room temperature 15°-30°C (59°-86°F).
d. May last indefinitely when stored in controlled room temperature.
e. It should be indicated that Lugol’s Solution should only be for EXTERNAL USE ONLY.

Reference: http://ftp.uspbpep.com/v29240/usp29nf24s0_m41243.html

https://dailymed.nlm.nih.gov/dailymed/getFile.cfm?setid=7d8f4f37-948c-4740-8e23-
2f23e47ebd5b&type=pdf&name=7d8f4f37-948c-4740-8e23-2f23e47ebd5b

KMnO4 solution for wound dressing

a. A potassium permanganate solution is made by dissolving crystals or powder in water aiming for
a 1-in-10,000 solution. Potassium permanganate tablets can also be used. If using 400 mg
tablets, add one to each 4 L of water. The tablets should be dissolved in hot water before
pouring into the bath. The potassium permanganate solution should be a pink colour.
b. The potassium permanganate solution may be used as wet soaks to blistering wounds such
as ulcers and abscesses. Strips of cotton or gauze should be soaked in the solution and
wrapped around the affected area for 20–30 minutes. The astringent action of potassium
permanganate helps to dry out the blister and prepare the wound for other treatment. For
wet dressings or baths, use approximately 0.01% (1 in 10 000) solution.
c. Store in a well closed container. Store at +15°C to +25°C away from combustible materials.
d. Stable under normal conditions of use and storage. Indefinite shelf life, store in cool, dry
environment.
e. Potassium permanganate crystals and concentrated solutions are caustic and can burn the
skin. Note that potassium permanganate may leave a brown stain on skin and nails as well
as the bath or vessel holding the solution. Use nail varnish or by apply soft paraffin to
fingernails and toenails before treatment.

References: https://dermnetnz.org/topics/potassium-permanganate/
http://www.druginfosys.com/drug.aspx?drugCode=590&type=1#StorageConditions

http://www.valentis.com/uploads/shop/docs/69_8359989405150401c445f8adde76128a.pdf

https://www.mccsd.net/cms/lib/NY02208580/Centricity/Shared/Material%20Safety%20Data%20Sheets
%20_MSDS_/MSDS%20Sheets_Potassium_Permanganate_Solution_0_1M_584_10.pdf

KMnO4 solution for Vaginal douche

a. A potassium permanganate solution is made by dissolving crystals or powder in water aiming for
a 1-in-10,000 solution. Potassium permanganate tablets can also be used. If using 400 mg
tablets, add one to each 4 L of water. The tablets should be dissolved in hot water before
pouring into the bath. The potassium permanganate solution should be a pink colour.
b. A 1% solution (1 in 100) is used as a direct application to treat fungal infections such as
those infections in the vagina. Twice daily baths for two days help to dry out the weeping
sores.
c. Store in a well closed container. Store at +15°C to +25°C away from combustible materials.
d. Stable under normal conditions of use and storage. Indefinite shelf life, store in cool, dry
environment.
e. Potassium permanganate crystals and concentrated solutions are caustic and can burn the
skin. Note that potassium permanganate may leave a brown stain on skin and nails as well
as the bath or vessel holding the solution. Use nail varnish or by apply soft paraffin to
fingernails and toenails before treatment.

40% Ethyl Alcohol

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b. Antiseptic and Disinfectant at 40% concentration
– Antisepsis of intact skin prior to injections and venopunctures
– Disinfection of latex stopper of infusion bottles and drug vials (except vaccines), latex injection
sites of infusion sets

c. Store below 25 °C. Away from sunlight. Close bottles tightly to avoid evaporation. Keep away
from sources of ignition (flame, spark, incandescent material).
d. Stable under normal conditions of use and storage. Indefinite shelf life, store in cool, dry
environment.
e. – Do not apply to mucous membranes, wounds or burns: it is painful, irritating and slows the
healing process.
– Do not apply on neonatal skin.

References: http://www.labchem.com/tools/msds/msds/VT270.pdf

https://medicalguidelines.msf.org/viewport/EssDr/english/ethyl-alcohol-ethanol-16687895.html

http://www.pharmacopeia.cn/v29240/usp29nf24s0_m1238.html
KCL Oral Solution

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b. Potassium chloride is a potassium salt indicated for the treatment and prophylaxis of
hypokalemia with or without metabolic alkalosis, in patients for whom dietary management
with potassium-rich foods or diuretic dose reduction are insufficient

• Adults: Initial doses range from 40-100 mEq/day in 2-5 divided doses: limit doses to 40 mEq per dose.
Total daily dose should not exceed 200 mEq (2.2)

• Pediatric patients aged birth to 16 years old: 2-4 mEq/kg/day in divided doses; not to exceed 1 mEq/kg
as a single dose or 20 mEq whichever is lower; if deficits are severe or ongoing losses are great, consider
intravenous therapy. Total daily dose should not exceed 100 mEq (2.3)

c. Store at 25°C (77°F); excursions are permitted to 15° to 30°C (59° to 86°F). [See USP Controlled
Room Temperature]. Dispense in a tight, light-resistant container as defined in the USP.
d. Manufacturers Expiry, no preservative, discard 7 days after opening; stored at room
temperature until opened, then store in fridge for 7 days
e. • Gastrointestinal Irritation: Dilute before use, take with meals

Reference: http://www.lupinpharmaceuticals.com/pdf/18/10/potassium-chloride-oral-solution-pi-
artwork-6-2018.pdf

https://cdhb.health.nz/wp-content/uploads/1907c646-potassium20chloride.pdf

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