ACUTE MYELOID LUKEMIA

PREDISPOSING FACTORS: PRECIPITATING FACTORS:

 Male sex  Did not come back for

 Age follow up check-up
 Repeated exposure

 to benzene

Alteration of the cell’s DNA structure

Proto-oncogenes
Bruises
Decreased Vitamin C
Gum 500mg
Oncogenes platelet count
bleeding 1tab OD

Activation of Tumor suppressor genes

but doesn’t work

Decreased Proliferation Increase numbers of •Neutrophils – 80.5% (HIGH)

Control immature WBC that •Eosinophils – 9% (HIGH)
are unable to •Monocytes – 15% (HIGH)
destroy or fight •Lymphocytes – 60% (HIGH)
microorganism
Cell Mutation

Increased WBC
Severe Bacterial and 18,000 /uL
Bone marrow Disrupted Genes Viral invasion
aspiration
•Neutrophil, total – 70% (HIGH) Immature clone of cells Cefuroxime
•Eosinophils -10% (HIGH) 500 mg IVTT
•Myeloblasts – 5% (HIGH) every 8 hrs.
•Myelocytes – 25% (HIGH) ANST
•Lymphocytes – 16 % (LOW)
Rapid proliferation of
•Plasma cells – 8% (HIGH)
•Myeloid: Erythroid ratio – 5 (HIGH) Abnormal Cells

Circulates the
Bone marrow bloodstream  HCT – 30% (LOW)
Decrease RBC
count  Hgb – 8 g/dL (LOW)

Formation of neoplastic
cells in the bone marrow Decrease O2 Pallor
Fatigue
concentration/
distribution in the
blood Increased HR Decreased O2
Myeloblast abnormality (100 bpm) sat (85%)

Mutation of abnormal cells Furosemide Blood

10 mg IVTT 30 Transfusion
mins. before BT and 1 unit of
after BT PRBC

Cell Differentiation arrest

Weight increased RR
Anorexia loss (35 cpm)
Immature clone of cells

Oxygen
Inhalation
Abnormal hematopoiesis 2 L/min. via
nasal cannula
Legend:

Precipitating & Predisposing Factors Not experienced by the client

Disease Process Treatment

Manifestation Laboratory Results

Experienced by the client Procedure