~ = 10, White R. Advanced: Oxford-Supplementary Skill 314 Ed. Oxford University Press; % > 2099, 11. Wong L, Essential Study Skills, 7” 12d, Wadsworth Publishing; 2011. i SECOND PROFESSIONAL r PHAI Course Objective: “The objective to teach dosage form science is to give the students knowledge about different Gosage forms used in pharmacy, their small and large scale preparation, formulation of dif JARMACEUTICAL CALCULATIONS: sat dosage forms, and their role in the practice of community pharmacy. ‘The Metric “System> The Fundamentals of Measurements and Calculations. Percentage calculations, Some -Common Systems. Conversions. Calculation. of Doses. Reducing and Enlarging Formulas. Weights and Volumes of Liquids. HEB Values. 1 Caloulations. Calculations involving parenteral admixtures. Some involving Hydrogen-ion “Industri Calculations involving isotonic, “calculations concentration. \d buffer solutions. - electrolyte a INTRODUCTION: Dosage form, Ingredient, Product formulation. Infusions, Decoctions, Extracts, Fluid extracts, +S “GALENICAL PREPARATIO! [Tinetures, Aromatic waters. 4, SOLVENTS USED IN PHARMACEUTICAL PREPARATIONS: - 5. ORAL SOLUTIONS, SYRUPS, ELIXIRS AND SPIRITS: Solutions: Preparation, dry solutions, oral colonic lavage * solution. mixtures for solution, oral rehydrate Syrup: components and preparation of syrups. Elixirs: Preparation of elixirs, Mediéated and non-Medicated elixirs. Spirits: Preparation of Spirits.2am . & ORAL SUSPENSIONS, EMULSIONS. MAGMA AND GELS: Preparations, ‘examples + and importance. a4 7; TOPICAL AND TRANSDERMAL DRUG DELIVERY SYSTEMS: Introduction of Ointments, Creams, Pastes, Poultice, Plasters, Lotions, Liniments, Topical gels, Topical Tinctures, Collodions, Topical solutions, Topical powders, Percutaneous absorptio, Transdermal systems in use. 8. OPHTHALMIC. NASAL AND OTIC PREPARATIONS: Ophthalmic solutions, suspensions, ointment, inserts, contact lens “solutions. Nasal decongestant solutions, Decongestant inhalers. ‘Ear preparations: Anti-infective, anti-inflammatory and analgesic. 9. SUPPOSITORIES AND ENEMAS: Semi-solid preparations, Suppositories: Bases, Preparation, packaging and storage; Solutions/Enemas: Preparation, packaging and storage. \0-AEROSOLS. INHALATIONS AND SPRAYS: Acrosol: Principle, container and valve assembly, propellants, filling, testing, packaging, labelling and storage. Inhalations: Principle, container and valve assembly, propellants, filling, testing, packaging, labelling and storage. Sprays: Principle, container and valve assembly, propellants, filling, testing, packaging, labelling and storage. .11. POWDERS, CAPSULES, TABLET DOSAGE FORMS: Preparation of Powders, mixing of powders, uses and packaging of powders, granules, effervescent granulated salts. Hard. gelatin capsules: Capsule sizes, preparation of filled hard gelatin capsules. Soft gelatin capsules: Preparation and its application. Tablets, their types, characteristics and methods of preparation. 7 12. DUCTION TO PARENTERALS: Official types of injections, solvents and vehicles for injections, added substances. 13. A BRIEF ODUCTION TO ORAL HYG! PRODUCTS:‘simple ‘syrup, Orange syrup, Ferrous sulphate syrup, Cod Liver oil Emulsion, Liquid -paraffin Emulsion, Throat paint (Mandle’s paint), Boroglycerine glycerite, Tannic ‘giycerin, Spirit ammonia aromatic, Spirit of Ethyl Nitrite. Preparation of Methyl salicylate ointment, Sulphur ointment, eal lotion, Iodine tincture, Preparations of oral hygiene products, Poultice of ala Effervescent granules, Distilled Water for _ conducted), — .__ injections (A minimum of 20 practicals will SUGGESTED READING! _ 1. Allen LV, Popovich NG, Ansel HC. Ansel's Pharmaceutical Dosage Forms and Drug Welivery Systems. 9"" Ed. Lippincott Williams & Wilkins; 2010. 2. Armstrong NA, James KC. Understanding Experimental Design and _ Interpretation in Pharmaceutics. 1°' Ed. Taylor & Francis Ltd; 1990. _ 3, Aulion ME. Autton's Pharmaceutics: The Design and Manufacture of Medicines. ~~ 1 3" Ed. Churchill Livingstone; 2007. a Bentley AO. Text book of Pharmaceutics. 8" Ed, Macmillan Publishing Co Inc; 1977. arstensen JT. Pharmaceutics of Solids and Solid Dosage Fi st ‘ ns Inc; 1977, ’ 'g¢ Forms. 1°” Ed. John Wiley HM. Bentley’s Text book of Pharmaceuticals. 24 £4, Tindall and Cxea A, Engel J, Kutscher B, Reichert D. Pharmaceutical Substances: Synthesis. _ Patents, Applications of the most relevant APIs. sth Ed. Thieme; 2008. ‘11. Lewis GA, Mathieu D, Phan RTL. Pharmaceutical Experimental Design. 18! Ed. - Informa HealthCare; 1998. | —) End W. The Pharmaceutical Codex: Principles and Practice of Pharmaceutics. 12! " - “'Ed. The Pharmaceutical Press; 1994. : 13. Mehta D. British National Formulary (BNF). 54! Ea. Pharmaceutical Press; 2007. 14. Rowe RC. Handbook of Pharmaceutical Excipients. 2009. oth Ed. Pharmaceuthal Press; Pp 15. Sinko PJ, Martin AN. Martin's physical pharmacy and pharmaceutical seiences: physical chemical and biopharmaceutical principles in the pharmaceutical sciences. 5‘" Ed. Lippincott Williams & Wilkins; 2006. 16. Winfield AJ, Richards RME. Pharmaceutical practice. gr Ed. Elsevier-~" of drugs. Median lethal dose (LD:50), ‘Median effective dose (ED:50) and Therapeutic Index, Dose-response relationshi 2. DRUGS ACTING ON AUTONOMIC NERVOUS SYSTEM (ANS): 2 a, Organization of ANS its subdivisions and innervations, b, Neurotransmitters in ANS, their synthesis, release and fate. ‘Sympathetic agonist drugs: Catecholamines and Non-catecholamines. d. Sympathetic antagonist drugs: Adrenergic receptor Blockers and neuron blockers. €. Parasympathetic (Cholinergic) agonists and _—_Anticholinestrase inhibitors. Parasympathetic antagonists f, Ganglion stimulants and Ganglion blockers g. Neuromuscular Blockers RACT: 3. DRUGS ACTING ON GASTROINTESTINAL a, Emetic and anti-emetics. b. Purgatives. c. Anti-diartheal agents. d. Treatment of Peptic ulcer: Antacids, H2-Receptor antagonists, antimuscarinic agents, proton pump inhibitors, prostaglandin agonists, gastrin _ receptor antagonist and cytoprotective agents. €. Drug treatment of chronic inflammatory bowel diseases. f. Drugs affecting bile flow and Cholelithiasis. 4, AUTACOIDS AND THEIR ANTAGONISTS: Histamine and Anti-histamines, Serotonin and Serotonin Antagonists, Prostaglandins and their antagonists. 5. DRUGS ACTING ON RESPIRATORY SYSTEM. ~* . Dewick PM. Medicinal Natural Products: Biosynthetic Approach. Wiley & Sons; 1997. 8. Evans WC, Trease GE, Evans D. Trease and Evan’s Pharmacognosy. 16 Ed. ith Sciences Publisher; 2009. 9. Forhne D, Plander HJ. Poisonous Plants: A Hand Book for Doctors, Pharmacists, inarians. 284 Bd. Timber Press; 2005. Elsevier Healt Toxicologists, Biologists and Vete iO. Harbome JB, Baxter H. The Hand Book of Natural Flavonoids. Willey & Son; 1999. 11. Jackson BP. Atlas of Microscopy of Medicinal Plants, Culinary Herbs and Spices. ond Ed. CBS Publishers; 2005 12. Khandelwal K. Praetical Pharmacognosy. gt Ba. Nirali Prakashan Publishers; 2008. 13. Lesley Braun and Mare Cohen. Herbs and Natural Supplements: An evidence Based Mosby; 2010. guide. 3" Ed. London: Elsevier oa 14. Lockwood B. Nutraceuticals: A Guide for Healthcare Professionals. Pharmaceutical Press; 2007.Products. John Wiley & Sons: 1981. : Alknfolds: Chemistry and Physiology. Academic Prest 1970, Chauhan. Ayurvedic Phe sac (08) 18 Bd.Son iF tical 42007. re 20 JA, Medicinal Plants of thy Wo 2" £4, Humar +19, Smith AB. Poisonous Plants of (Cntr 2M gq. pod) Exp 20k; 1988 20. Smith AB, Poisonous Plants »f at! Coun ies: With t Ace, Ch aic:| Principles Which They Contain; and th Tevic Syr toms Prod) dy Bach iro p. 4th pd. General Books LLC; 2010. 21. Tyler VE, Brady LR, Robbers Ji P arma jnsy. 10" d, and Febiger; 2001. 22, Wichtl M. Herbal Drugs and hy opha aceuticals. "4, Medpharm Publishers; j e NX. 4 a 2004, : are ~~“) PHARMACEUTICS-INl (PHARM. M_ CRO LOGY M (NOLOGY) (Theory) Marks 100 _ Course Objectiv« Sy Students shall be taught tl the principles of Rate) with special reference to Pharmaceutical Microbiology including environmental Microbioiogy and other relevant aspects. The modem “concepts of microbiological application shall be taught to students. ‘The staining of slides and ion of culture, media, etc., including, migcbioieaiat assays of Pa shall be4 cial reference to Pharmaceutical Sciences, Nomenclature and | Organisms, et a. The Bacteria: General and cellular Morphology, structure and function. Classification of Bacteria. Growth curve, growth factors and growth characteristics. — Nutrition requirements and nutrition factors affecting growth. Culture Media, E _ Bacterial cultures and staining Methods. b. The Viruses: Introduction, Classification (and detail of at least one species from ~~ every group), cultivation and replication. =e. The Fungi olds: | y ‘ | ~~ d. The Protozoa: * 3. THE NORMAL FLORA: Microbiology of air, water aad soil (general introduction nd normal inhibifknts of air, water and soil). | 4. INDUSTRIAL MICROBIOLOGY: Introduction to Sterilization’ Disinfection. Fermentation. Pharmaceutical products Produced by fermentation process (Penicillins, ‘Cepalosporins, Gentamycin, Erythromycin, Tetracyclinés, Rifamycin, Griseofulvin). ' r ae “ie 5. IMMUNOLOGY: Introduction and types of Immunity: Specific and non-specific | ' (Cellular basis of Immune response. Immunity, autoimmunity, tolerance. Antigen. Antibodies). Auitigen-Antibody reactions and their clinical and diagnostic applications. Hypersensitivity ‘and allergy. Drug allergy mechanism. Vaccination: i is a eosin Introduction and aims. Types of D_Goop Control of microbial contamination during, a ues, A Guide to Current Good Pharmaceyticat Mi Jaccines. Current vaccine practices._ To enhance understanding of the students regarding Islamic Civilization 3 To Students skill to perform prayers and other worships ; 3. To enhance the skill of the students for understanding of issues Related to faith and, religious life. 4 1. Introduction to Quranic Studies: a 1. Basic Concepts of Quran : 2. History of Quran 3. Uloom-ul-Quran ‘2. “Study of Selected Text of Holly Quran: 1. Verses of Surah Al-Baqra Related to Faith (Verse No. 284-286) i 2. Vetses.ofSurah Al-Hujrat Related to Adab Al-Nabi (Verse No. 1-18) eo etn i 3, Vetses of Surah Al-Mumanoon Related to Characteristics of faithful (Verse No. 1- =a of Surah al-Furqan Related to Social Ethics (Verse No. 63-77) of Surah Al-Inam Related to Ihkam (Verse No. 152-154)-MATICS AND. BIOSTATISTICS) (Theo 3 Paper 6 | Marks 100 | 6 a : [CE-I (PHARM. MATHE! Course Objective: Mathematics is the language of science. The study mathematics is important as all the equations used in pharmacokinetics and pharmaco-dynamics are in the mathematical forms and studies of such results are in logarithmic and integration forms. (40 MARKS) PART A: (PHARMACEUTICAL MATHEMATICS) als ALGEBRA: a. Solution of Linear and Quadratic Equations: Equations reducible to Quadratic Form. Solution of simultaneous Equations. rogressions: Arithmetic, Geometric b. Arithmetic, Geometric and Harmonic and Harmonic Means. c. Permutations and Combinations: 4. Binomial Theorem: Simple application 2. TRIGONOMETRY: Measurement ‘of Angles in Radian and Degrees. Definitions of circular functions. Derivation of circular function for simple cases. 3. ANALYTICAL GEOMETRY: Coordinates of point in a plane. Distance between - inz, Equation of Parabola, Circle and Ellips. two points in a plane. Locus, Equations of straight 4. DIFFERENTIAL CALCULUS: Functions, variations in fimetions, limits, _» coefficient, differentiation of algebraic, trigonometric, exponential and functions, pe ; Pa ‘ partial derivatives. Maxima and minima values. Points of inflexion. 1, CALCULUS: Concept of integration, Rules of integration, INTEG Integration of algebraic, exponential, logarithmic and trigonomet ic fictions by using different techniques and a! cal integration. ‘ 11 - i1. Daniel WW. Bio-Statistics: Foundation for Analysis in Health Science. oth Ed. Wiley Publishers; 2009. i ‘ 2. Nilton JS. Statistical Methods in Biological and health Sciences. 3d Ed. McGrew 4 i 3 7 Hill; 1998. 3. Hoel PG, Port SC, Stone CJ. Introduction to Statistical Theory. 1" Ed, __ Brooks Cole; 1972. Samuels M. Statistics for the life sciences. 3™ Ed, Dellen Publishers co; 2002. 5. Zar JH, Biostatistical analysis. 4" Ed, Francis Hall; 1999. » THIRD PROFESSIONAL