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SCHEME OF VALUATION
Action potential:
When the cell is excited, then the cell membrane changes its characteristics.
The permeability of cell membrane to sodium ions (Na+) increases and it
allows some of Na+ ions to enter. The ionic flow of sodium further reduces
the barrier of membrane to sodium ions.
At the same time, K+ ions, which were in higher concentration inside the
cell during resting state, try to move outwards, but at a slower rate.
This potential is known as the action potential. The typical value of action
potential is +20mv.
OR
Time Typical time Physical Polarisation Typical
intervals in in normal activity phase amplitude
cardiac cycle heart
P – wave 0.1 – 0.15 sec Completion of Complete 0.1 to 0.3mv
atrial depolarization
contraction of atrium
P – Q interval 0.15 – 0.16 A – V node Start of
sec triggered depolarisation
of ventricle
muscle
QRS wave 0.05 – 0.1 sec Ventricular Completion of 3 to 4mv
contraction depolarisation
of ventricle
muscle and
atrium muscle
repolarisation
S – T interval 0.05 – 0.15 Ventricular
sec contraction
continues
T – Wave 0.2 sec Ventricular Repolarisation 0.1 to 0.5mv
muscles of ventricle
return to muscle
resting state
Microwave diathermy:
Microwave:
They are electromagnetic radiation with frequency range of 300 – 30000MHz
and
wavelengths varying from 10mm to 1m. They lie between short waves and IR
rays in the electromagnetic spectrum. The most used microwave frequency for
therapeutic heating is 2450MHz corresponding to a wavelength of 12.25cm.
Delay circuit: The magnetron has to warm up for 3-4 min before power is
derived from it. A delay circuit connects anode supply to the magnetron and a
lamp lights up indicating that the apparatus is ready for use after 4 minutes.
Magnetron circuit: The magnetron filament heating voltage is obtained directly
from a separate secondary winding of a transformer. The filament cathode circuit
has interference suppression filters. The anode supply to the magnetron can be
DC or AC. DC voltage is obtained by a full wave rectifier followed by a voltage
doubler circuit. A high wattage variable resistance, connected in series controls
the current applied to the anode.
Safety circuit: A fuse (500mA) is inserted in the anode supply circuit of the
magnetron, to protect the magnetron from damage due to excessive flow of
current. The considerable interference produced by the apparatus necessitates the
use of large self-inductance coils in the primary supply. Since the cores become
saturated due to the small dimensions, the coils are split up and fitted such that
there is no magnetization.
MCH: The mean cell haemoglobin is the ratio of haemoglobin (Hb) count to the
red cell count. It is expressed in pictogram.
MPV: It is the ratio of the integrated platelet volume to the platelet count and is
expressed in femoliter.
RDW: The RDW measures the deviation of the RBC width, not the actual width
or size of the individual cell.
The most important indicator of chemical balance in the body is the “pH” of
the blood and other body fluids.
In pH metry we deal exclusively with the concentration changes of
hydrogen ion in solution.
The term ‘pH’ refers to free hydrogen ion concentration.
Working of digital pH meter:
Buffer amplifier:
The buffer circuit is one kind of emitter follower and is generally used for
impedance matching.
Summing Amplifier:
The output voltage of pH electrode is very much low.
Display System
It is used to display the output in the form of digital.
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PART – B
10. (a) What is electrode? Mention the types of electrodes.
The electrodes are used to pick up the bio electric potential from the body or
converts the quantity to be measured into a usable electrical output.
OR
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The electrodes are used for picking up the bio electric events of the body for
measuring the potentials and currents in the body.
The bio current is carried within the body by ions and carried in the
electrodes and associated wires by electron.
Because the electrical characteristics of the electrodes specify the type of
amplifier.
Types of electrodes:
Mainly there are four types of electrodes are:
1. Micro electrodes.
2. Needle electrodes (skin electrodes).
3. Surface electrodes.
4. Indwelling electrodes.
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11. Illustrate the 10 – 20 3electrode placement for EEG with neat diagram.
In EEG the electrodes are placed in standard positions according to committee
of international federation of societies for EEG on the skull and this
arrangement is called 10 – 20 system. There are 21 electrode location in this
system.
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Electrodes are named according to their positions on the skull like FP for
frontal polar, F for frontal, C for central, P for parietal, T for temporal and
O for occipital, Z denotes the middle line.
Odd number are given to electrodes on the left side. Even numbers are
given to right side of the head.
The reference electrode is placed on the midline forehead.
In this system the electrodes are placed at the distance of 10% and 20%.
These distance are the measured distances along coronal, sagittal and
circumference arcs on the skull.
Procedure:
Draw a line on the skull from nasion to the inion.
Draw a same type of line from the left pre auricular point (ear) to the right
pre auricular point.
The intersection of these two lines is marked as CZ.
Mark the points at 10, 20, 20, 20, 20 and 10% of the total nasion – inion
distance. They marked as FP2, F8, CZ, PZ and 02 on the right and FP1, FZ, CZ,
PZ and 02 on the left.
Mark points at 30, 20, 20 and 30% of the total nasion inion distance along
the midline. These points are FZ, CZ and PZ.
mark the points at 25% along the circumferential passing through C 3
between FP1 and O1 on the left side as F3, C3, P3 and passing through C4
between FP2 and OZ on the right side as F4, C4 and P4.
Ear electrodes A1 and A2.
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OR
Both bipolar and monopolar techniques are used in EEG electrode systems.
In bipolar technique, the potential difference between two adjacent
electrodes is measured.
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12. Mention the application of ECG, EEG, EMG and ERG. (any five
applications each).
Applications of ECG:
Heart rhythm.
Diagnose poor blood flow to the heart muscle.
Diagnose a heart attack.
Diagnose cardiac abnormalities such as heart chamber enlargement and
abnormal electrical conduction.
Detection of heart arrhythmia, cardiac abnormalities.
Portable ECG is used in telemedicine. It is used in primary health care units
where trained cardiologists are not available.
Applications of EEG:
Depth of coma.
Brain disorders.
Depth of anesthesia.
Migraine variants.
Epileptic seizures.
Brain death.
Applications of EMG:
Neuro muscular diseases.
Kinesiology.
Disorders of motor control.
To control signal for prosthetic devices.
To sense isometric muscular activity.
Unvoiced speech recognition.
Applications of ERG:
Used by opthomologistis and optometrists.
Diagnose of various retinal diseases.
Inherited retinal degeneration.
Diabetic retinopathy.
Autoimmune retinopathies such as cancer associated retinopathy.
Retinal detachment.
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Then the discharge current passes through fencing transformer placed in the
circuit. The current fencing transformer provides ground isolation for
patient circuit and also measured the discharging current through patient.
The transformer detects the peak voltage and gives it to microprocessor for
recording. Microprocessor take discharging current and stored energy to
determine the patient’s impedance and delivered energy.
The delivered energy is converted into a digital format by the means of A to
D converter for displaying the recording on monitor.
The poor paddle (electrode) contact warming is activated when patient’s
impedance exceeds the 100ohm. Thus the microprocessor based
defibrillator provides the control range of energy to be delivered for patient
requirements and there is a provision for an operator to have a control over
the delivering energy, thereby increasing effectiveness.
14. What is laser? List different types of lasers. Mention its application in
medicine.
LASER is light amplification by stimulated emission of radiation.
Laser light is highly monochromatic energy, thereby increasing
effectiveness.
The word laser has been derived by taking the first letters of the expression
light amplification by stimulated emission of radiation.
It is an extension of the maser to the optical region of the electromagnetic
spectrum the laser is used as a generator of light.
Types of laser:
1. Ruby laser.
2. Nd – YAG laser.
3. Helium – neon.
4. Argon laser.
5. Krypton laser.
6. Co2 laser.
Applications of laser:
1. Neurosurgery.
2. Treatment of detached retina.
3. Gastroenterology.
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M – mirror.
L – lamp.
S1 – entrance slit.
S2 – exit slit.
C – Cuvette, in which sample solution
whose absorbance or transmittance is
to be measured, is taken.
D – A sensitive photodetector (often a
photoelectric cell).
G – Grating.
Light from the radiation source ‘L’ is allowed to pass by means of a lens,
through a narrow slit ‘S1’ and then by means of a mirror ‘M’, to an optical
grating ‘G’, which divides light into narrow spectral region corresponding
to different wavelengths.
An exit slit ‘S2’, selects a narrow band of the spectrum, which is used to
measure the absorption of a sample in the cuvette ‘C’.
The narrower the exit slit, the narrower the bandwidth of the light.
The light of a desired wavelength emerging from the exit slit ‘S2’ is
allowed to pass through the cuvette ‘C’, contact with a galvanometer ‘G’.
The intensity of light which is measured by the deflection in the
galvanometer, is recorded.
The cuvette C, is now replaced by another cuvette containing pure solvent
and the same light is allowed to pass through it and then to photoelectric
cell ‘D’.
The intensity of light is again measured by the deflection in the
galvanometer, as before.
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The physiological effect of the current depend not only on their magnitude
but also on the current pathway through the body, which is turn depends on
the location of the first and second contacts.
Depending on how the currents are introduced into the body, there are two
particular situations:
When both contacts are applied to the surface of the body (macro shock).
When one contact is applied directly to the heart (micro shock).
A micro shock can be applied by applying the current inside the body.
In micro shock the current doesn’t have to pass through the high resistance
of the skin.
It instead follows the arteries and passes directly through the heart.
Hence, ventricular fibrillation can be induced with micro shock current
levels that are much smaller than the current levels needed to induced it
under macro shock conditions.
In AC defibliator a brief (0.25 to 1 sec) burst of 60 – Hz AC with an
intensity of around 6A is applied to the chest of the patient through
appropriate electrodes.
The application of electric shock to resynchronize the heart is sometime
called “counter or macro shock”.
Falling prices.
Planned obsolescence.
E waste treatment and disposal method:
Landfilling.
Incineration.
Recycling of E waste.
Reuse.
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