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    2010 xu XL : LIFE SCIENCES Duration : Three Hours Maximum Marks :100 Head the following instructions carefully, |, This question paper contains 24 pages including Plank pages for rough work. Please check all pages and report discrepuney. tan. 2. White your regéiration number. your name and name of the examinatian cente al ihe specified locabons on the right hall of the Optica Response Sheet (OHS) 3. Using HIB pena) darken dhe appropriate bubble under each dignt af your registration qunnber and the leters comesponding 10 {Jour paper code. 4. Allthe questions in dis quesuon paper are of object rye. 5. Questions must be answered on Optical Response Shect (ORS) by darkening the approprlae bubble (marked A, B, C. D) ‘sing HB. peseil against the question oumnber on the lf hand side OF the ORS. For each question darken the DuDDIE of the correct anewer, In case you wish to charge an answer, erase the old answer completely. More than one answer bubbled sgzanst a question all be taken at an incorrect response, 6, There ave artal oF 65 questions canying 100 marks. 1. This question paper contains alx sections as Usted below. Sec cade scumpulaan sxqions Conse (ve wore sions foe the rerianing sections Latzough ©, Section rage Wo. | Section Pare No, GA. Generel Aptitude or [t. Botany 20 1 Chemisry 4 | K Microbioigy 5 1 Biochemisny 0 | L zeotngy 1 Using HIB pencil. mark the sccions you have chosen by darbering the approprice bubbles on the lel hand side of the ORS. provided. Make sure you have correctly bubbled the sections yoo hare chosen. ORS will ot be evaluated it this information le NOT marked. 8. There are 10 questions carying 15 marks in General Aptisade {GA) section, which is compulsory. Questions @.] -Q5 will carry ferack each, ard questions 6 - Q.10 will earyy 2-marks euch, 9. There are 15 questions cazrying 25 mavks in Chesaisury section paper (Section H), when is commpulsory. Questions Q.4 5 ‘ll cary t-mavk cath, and questions Q6 ~ Q.15 will cary ?-murks each comaining 1 pur of common data and ? paur of Uinkea questions. Questions Q.12 ard Q.13 (I pait) are corimon data questions with 2-marks each, and questions ©. 14 and 2.15 {U poin) ae Linked answer questions with 2+marks each. The answer to the secre) question of the Inked answer questions depends on the answer tothe first question of tke pair. IF he fre question in the bnked pairis wrongly anewered (ors unatempted. them the znswer Wo th second question inthe par wll not be evetusted, 10. Each of he other XL section papers (Sections | through 1 eortains 20 questions canying 30 make. Questions Q1 - Q.10 vill carry Lerark each and questions Q 1? - Q.20 will camry 2-marks each U1. Un-auerpted questions will cazry zera mats, 12. Wong answers will cory NEGATIVE marks. In GA, for Q.1 = Q.5, % mark will be deducted for each wrong answer and for Q.6 - Q.10, % mark Wall be deducted for each wrong answer. In XL Section H, fer Q.1 O15. % mark wil be deducted Fer each wrong answer and for 0.6 ~ 0.13, 3 mark wil be deducted fer each wrong answer, The question ptir (Q-14, Q.415) is questions wit linked answers. There will be negative marks anly For wrong aaswer to the first question of the ‘inked answer question pair. Por Q 14. mare will be deducted fr weong answer, There tno negative marking for Q.15. In all ‘other XL, ection papers (Scion i through L). fer Q.1 = Q 10, «nak il be deducted for eack wrong ansver ard fo¢ Q.11 =Q220, & mark wil be deducted foreach wong answer 15. Calculator ¢without data coneectivty) is alowed in the examination ball 14. Cars, graph sheets or ubles are NOT allowed in tke examination hall 18, Rough wark ean be done om the question paper liselt. Addnuoralty. Bink pages re provided at Ce end af the question pape far ough werk, xl. 1a 2010) aL GA: General Aptitude (Compulsory) Q.1-Q.5 carry one mark each. Qt Q2 Qa Qa Qs The question below consists of « pair of relaied words followed by four pairs of wards. Select the pair that best expresses the relation in the original pair. ‘Unemployed : Worker (A) fallow : land (B} unaware: sleeper EC) wit: jester {D) renovated ; house Choose the most appropriate word from the options given below io complete the following sentence: ‘His rather casual remarks on politics. (A) masked (B) belied (C) betrayed {D) suppressed Wich of the following options is the closest in meaning to the word below: Cirewitous iA) cyclic {B) indizect (© confusing {D) crooked his lack of seriousness about the subject. 25 persons are in a room. 15 of them play hockey, 17 of them play football and 10 of them play both hockey and football, Then the nuraber of persons playing neither hockey nor football is: (a2 B17 ©B @)3 Choose the mast appropriate word from the options given below to complete the following sentence: ‘our natural resources, we would leave a better planet for (A) uphold GB) restrain (C)cberish D) conserve Q.6- Q.10 carry two marks each. a6 Qr 5 skilled workers can build a wall in 20 days: 8 semi-skilled workers can build a wall in 25 days: 10 unskilled workers can build a wall in 30 days. $f a team has 2 skilled, 6 semi-skilled ard 3 unskilled workers, how long will it take 10 build the wall? (A) 20 days (8) 18 days (©) 16 days {D) 15 days Given digits 2. 2.3, 3, 3, 4, 4, 4, 4 how many distinct 4 digit numbers grea than 3000 can bo formed? ayo «B51 52 (Dy $4 th 200 Q8 101374276 = 435 how much is 731 + 672? (aysa4 4B) 1403 «) 1623 (Dy 1513 QS Hari (4), Gite (G). Irfan (1) and Saira (S) are siblings (Le. brothers and sisters). All wore born on 1" January. The age difference between any (wo successive siblings (Ihat is born one after another) is less than 3 years. Given the following facts: i. Hari's age + Gita's age > Irfan's age + Saita's age. 4L, The age difference between Gita and Saira is I year. However, Gita is not the oldest and Saiea is not the youngest. iii. There are no twins. In what order were they born (oldest first)? A) HSIG (B) SHI (©) IGSH @) ISG Q.10 Modern warfare has changed from large scale clashes of armies to suppression of civilian populations. Chemical agents that do their work silently appear (o be suited to such warfare; and regretfully, there exist people ix military establishments who think tlt chemical agents, are useful tools for their cause. Which of she following statements best sums up the meaning ofthe above passage: (A) Modern warfare has resulted in civil strife (B) Chemical agents arc useful in modern warfare. (C) Use of chemical agents in warfare would be undesirable. (D) People in military establishments like to use chernical agents in war. END OF SECTION - GA 3024 zero Qi- Qu Q2. Q3. a4 Qs. Q6- 06. Q72 Q8. x H: CHEMISTRY (Compulsory) Q.5 carry one mark each, For a spontaneos process. the total entropy change (AS ne, + AS wenuatans) (A) equal 10 zero (B) greater than zero (C) less than zero for endothermic process _(D) less than zero for exothermic process A battery delivers a steady current of 1.25 A for 90 minutes. The total charge “Q’ fin Coulomb units) is (A) 6750 (B) 1012.5 ius (D125 Molecule that has no lone pair of elecerons on the central atom (among the choices) is (A) KeFs (B) PF: (C) CHS (D) BF; ‘The oxidation state of nicke! atom in the coordination compound [Ni(NHs);C1JC1 is wel (Bo (©) 41 «D) 42 ‘The compound that is aromatic, among Une choices, is »“OV=> Ge Oe Q Q.15 carry two marks each. Consider the following equilibrium reaction: CO (g) + Ch (g) —» COO: (g) 0.60 atm of CO and 1.10 etm of Cl, were mixed in a constant volume reaction vessel at a particular temperature, After the equilibrium was established, 0.10 atm of COCK was observed. The ‘equilibrium constant for the reaction is (aon (B05 02 66 For a particular reaction, the use of a catalyst reduces the activation energy (E,) to one-third its original valve. The ratio of rate constants (Keay f Kuta) 35 2£, ‘e D FL @. (BB © om( 22) ye ) ‘Among. heptan-}-ol. heptan-2-01, heptan-3-o! and heptan-4-ol, compounds those exhibit optical activity are (A) heptan.2-ol and heptan-3-o1 (B) beptan-2-0} and heptan-4-o] (C)hepun-3-al and heptan-4-ol {D) heptan-I-of und heptan-4-o} ua x Q9. Structure of the compourd ¥ in the following reaction sequence is Bt, kKorbu OC AcOH x ‘ Br “OO «O90 Q.10. The ionization energy follows the order (A) OF > 02> O07 >0;" (B) O:> 0, > 2 > OF (Oy > 07 > 0." > 0, (D) 0.7 > O,> OF > QUL Reaction of Na;SOs with 2 equivalents of HCI produces a gas X. Solution of X in water is acidic in nature, X is (A) Or (8) Ch (© D) Hs Common Data Questions ‘Common Data for Questions 12 and 13: Fhe ionization constants of phosphorous acid (HjPO;) are Ky = 3X 107; Ka = 17x 107 Q.12. For # dilute solution of phosphorous acid in a pH 5 buffer, the predominant species is (A) HPO, (B) H.POs (C) HPO; (py POS QU3. The structure of phosphorous acid is (Hoon ® ony oon 8 he 4 oon () HO-P © me S 1 $ i» xt 34 200 x Linked Answer Questions Consider the reaction sequence "9 (CH,00),0 x i. By) NaOH Semen annydrous AIC, aier product) ii H,O* Q.14. The structure of X in the above reaction sequence is “Cy ° mond © “Oy a ok ) Meo. » CL. Q.15. The structure of Y in the above reaction sequence is on Meo. er “ @) Cr Meo, Meo, ° oO. on Br 3 END OF SECTION - H XU 64 20w “T: BIOCHEMISTRY Q.1-Q.10 carry one mark each. QL Q2. Q3. Qa. Q6. Q7. 9. Qo, Que Qu. Nucleolus is involved in the synthesis of (A) RNA (B)RNA «C) DNA. (D) mRNA In tryptophan operon, tryptophan aets as (A) Repressor ®) Activator {C) Corepressor —_(D) Co-activalor Positive selection of T cells ensures (A) MHC restriction {B) Self tolerance (C) TCR engagements (D) Activation by co-stimulatory signal A DNA-binding motif is (A) Helix-loop-helix (B) Helix-turn-helix (C) Helical wheel {D) Loop-helix-loop Amino acids responsible for N-linked and O-linked glycosylation of proteins are (A) Asparagine and Aspartic acid (B)Gloamine and Serine (C) Glutamic acid and Serine (D) Asparagine and Threonine ‘One of the following compounds is NOT a neurotransmitter {A} Dopamine (B) Glutamic acid (C) Histidine (D) Glycine. Approximate molecular weight (kDa) of the product after translation of a 390 bases mRNA will be aa B)26 39 mid Lineweaver-Burk plot is a plot of t ®) vy, ws [5] © 2 ssfs] Yo (© v% vs A. mixture of proteins (W. X, Y, Z} elute from Sepharlex G-200 column in the order W. X, Y,Z. ‘The protein with maximum electrophoretic mobility on SDS-PAGE will be ww Bx oY Oz Specific precursor for all prostaglandins is {A) Oleic acid (B) Arachidonic acid (C) Patmitic acid (D) aL inolenic acid Q.20 carry two marks each. ‘Chymotrypsin and lysoryme are involved respectively in P. Removal of successive carboxyl terminal residues Q. Hydrolytic cleavage of peptide bond R. Cleavage of glycosidic C-O bond S. Oxygen transport in blood (P.Q BQR Qs ORS XL 72a 2010 Q.12. Match the items in Group 1 with those Group] P. Isotype switching Q. Clonal anergy R Chass MHC 8, Selftolerance (AJP. O45, RB, S-2 (O)P-1,Q3, RAS2 Os. in Group 2 Group 2 |. Vy domain 2. Non-responsive to self antigen 3, Non-responsive Ty, cells 4, Brmicroglobulin (B) P-2, Q4. RL, $3 WD) P2QULRS. St Multiple RNA polymerase transcribes a DNA template, unwinding about 1.5 turns of DNA template per wanscription bubble. From the structural information of classical B-DNA, how many transcription bubbles are possible for a 18U base pair DNA molecule? (ale (B)27 QA. Group t P. Mixture of glycine and albumin Q Mixture of 26 and 60 kDa proteins R. Histones from nuclear extract S. Leetins (API,Q4,R3, $5 (C)P2.Q4, R46, Q.15. In the two alf reactions Acetaldehyde + 2H" +2e — Ethanol NADH +H ->NAD' + 2H’ +207 (F= 23,003 ca) ‘The A G? for coupled reaction will be (A) #7,400 cal (B)~7.400 cal O16, Group] Pky Q Kear Roe Roky SK, (AES, QA, R-2, $4 (CPA, Q-2, Red, 5-3 Qar. os @) 270 Match the items in Group 1 with the most appropriate separation techniques in Group 2 2 1. Gas chromatography 2 Dialysis 3 Affinity chromatography 4, Size exclusion chromatography 5. Thin layer chromatography 6, Cation exchange chromatography (B)P-5,Q3,R-4, 8-1 (D) P46, 5, R284 BE’=-0.16 V AEB=-032 V (C) -22,200 cal (D) 422,200 cal Match the parameters in Group 1 with the correct options in Group 2 Grow 2 Catalytic efficiency of the enzyme Affinity of enzyme te the inhibitor Affinity of enzyme to the substrate Maximum buffering capacity (BY P-3, QU, R-4, 8-2 {D) PA, Q4,R-2,8-3 “The rise per residue of achelix is about 1.5 A. A proicin spans 4 nm bilayer 7 times through its transmembrane a-helical domain. Approximately. how many amino acid residues constitute the transmerubrane domain of the protein (a) 105 (B) 450 XL 1) 30 Dy 199 ena aa x Q.18. Match the proteins in Group 1 with their comect functions in Group 2 Group 2 P 1. Inner membrane receptor Q Bacteriorhodopsin 2. Active transport R Porin 3. Voltage gated K* channel S. ABC transporter 4, Light driven H* pump 5. Membrane fusion 6. B-barrel simple diffusion chanel {A)P4,Q2, R555 BPS, Q5.R4,S6 (OP46.Q1.R5,S4 (@)P3,Q4,R6,S-2 Q.19. The metabolic disorders, Alkaptonuria and PhenyTketonuria are caused by defects in the enzymes P. Glucose- 6-phosphatase Q Phenylalanine hydroxylase R. Homogentisatel.2-dioxygenase S, Tyrosinase AVQR (BYP, COP,.Q Mas Q20. Match the metabolic pathways in Group 1 with the corresponding enzymes in Group 2 roup I Group 2 P.B-Oxidation 1. Ribulose bisphosphate carboxylase Q Glycolysis 2, Phosphofruciokinase 1 R. Gluconeogenesis 3. Phosphoenol pyruvate carboxykinase S. Calvin cycle 4. Thiolase ‘5. Phosphofructokinase 2 {A)P4,Q2,R3, 55 @B) P-3.Q-2.R-4, 8-1 CC)PB.QUR-S, 8-2 ) P-4,Q2, B-3, SL END OF SECTION -I x 974 aw J:BOTANY Q.1- Q.10 carry one mark each. Ql. Od Q3. Q4. Qs, Q0. Q? xh ‘When chunges in the phenotype er gone expression occur withost changes in the underlying DNA sequence. the phenomenon is called (A) Mutation, [B) Eugenics «C1 Epigenetics (W) Epistasis A population growing exponentiatly can be described by the differential equation dNfdt = rN, where divide represents the rate at which the whole population grows, N is tho size of the population. ris the intrinsic rate of increase. and is time. According to this equation, the per capita rate of growth is (A) Highest atlarge © (B) Constant (C) Lowest al large N (D) Highest at small N Which one of the following is NOT a plant hormone? {A)Abscisic acid (B) Brassinosteroid (C) Ethylene (D) Cytokine Arabidopsis and rice have diploid chromosome numbers of 10 and 24, respectively. Assuming no crossing over taking place, genetic variation among F, individuals in a genetic cross is Hikely wo be (A) Sante in both species but not ze10 (B) More in Arabidopsis (C) More in rice (D) Zero in both the species Which of the following statements is CORRECT? (A) Plants adapted to cold environment have higher ratio of “unsaturated (0 saturated” fatty acids in their membrane compared to those adapted to hot environment (B)Plants adspied to cold environment have lower ratic of “unsaturated to saturated” fatty acids in their membrane compared to those adapted to hot environment (C) Plants adapted to cold environment have same ratio of “unsaturaced (© saturatcd™ fatty acids in their membrane compared to these adapled to hot environment (D) Plants éo not have any unyacurated fatty acids in eke merabrane A sign is hammered into a wee wrunk 2 meters above the uce’s base. Ef the trec is 10 meters tall and elongates | meter each year. how high will the sign be after 10 years? (12 meters (B)7 meters (C) 4 meters {D) 2 meters, Ia the arrangement of floral parts in a bud, identify the INCORRECT statement (A) Valvate: where the petals or sepals do not overlap but simply touch one another by their Mergins (8) Seabrous: petals rough and harsh totouch (€) Epicalyx: an exica calyx found in some flowers outside the calyx (D) Imbricate: where sepals ad petals overlap each other atthe margin 124 xt ai Q8_— The possible genotypes of endosperms bore on 2 heterozygous (Rr) plant will be. (A) RRR. RRe. Rex, (B) RRs, Rr (CORRRs (D) Re Q.9._ The amount of chemical energy available to consumers in an ecosystem is best represented by (A) Gross primary production (©) Respiration (B) Net primary production (D) Photosynthesis, Q.10. Free radical scavenging aciivity of a medicinally importam planl exiract can be quantified by {A) ABTS (2.2°-azino-bis(3-ethyl benzothiczoline-6-sulphonic acid)) method {B) Bradford method (©) Walkley and Black method {D) Kjeldahl method Q.11 ~ 0.20 carry two marks each. QUEL Identify the CORRECT statements from the following P. Lemticels are the smal! pores present on the surface of the stem or branches of woody plants, Q. Glyoxysomes contain chlorophyll molecules in their thylakoid membranes R. The enzyme ribulose |, 5 bisphosphate carboxylase is otherwise known as catboxydehydratase, S. 18 ATP and 12 NADPH molecules are utilized for fixing 6 molecules of CO; reaction of photosynthesis PQ @)PR QU2. Match the following Group 1 P. Sorghum Q. Castor R. Mushroom, S. Cotton (A) Pedeih, O54, ROI, Sly (C) P25. Q5-v, Riv, S-6eii the dark QR MPs Group II Group I 1. Gossypol i Protein 2. Steychnine Glycosidic conjugate 3. Dhursin Alkaloid 4, Bungarooxin Polyphenal 5. Ricin y. Lipid 6. o-Amanitin vi. Cyclic peptide sti, Queiv, Rai, Sev 5, Qi, Rotiv. S-Ly xt 11724 019 . . _ x Q.13._ Identify the correct match Group 4 (Anther) Group Il (Type of fixation) P Q 1 Basified 2 Longitudinal 3. Dorsifixed 4 Adenate 5 Porous 6 Versatile R s {AP Q4,R-6,$-3 (BYP-2.Q-3,R5,S6 (C)PA.Q2R6S5 (D)PA.QI.R5S.S-6 Qu4. From the structures given below, identify the compounds Group I (Structure) Group If (Compound) PB 1 Ethylene oy 2 Indole butyric acid 3. Nicatine 4 Indole acetic acid om 5. Gibberellie acid wea, 6 Memhot R 8 CHy= CH, O (00H t a (A)P-6.Q3.R4$-1 (B)PS.Q2R3S1 (C)P-4.0-3,R-2, 8-6 (D) P-1,.Q-2.R-5, 5-6 Q.15. Regarding the relationships between two organisms in an ecosystem. match the following Group | (Relationship) Group II (Definition) P, Commensalisin 1 Both organisms are benefited Q Mutualism 2. One impeding the success of the other R Parasitism 3 One organisin benefits but the other is unaffected S. Amensalismn 4 One benefited, other is harmed APL Q2R3 54 (BIP2O3R4S1 (CUPL QARAS2 (DP Q4 R352 XL 12724 xt oo Q.16. Name the stmctures given below in the order of their appearance and identify corresponding glycosidic linkages 4 ae eon aan nox one : 2. » Kee] Ban A NaN ae pe wc on B ot BA © on mon a on (A) Amylose, Cellulose; (al—4), (B16) {B) Cellulose, Dextran: (B24), (3-6) (C) Starch, Cellulose; (a -»6), (al—-4) (D) Amylopectin, Amylose; (a!-»6), (e1—4) Q.17. Identify the CORRECT statements In Arabidopsis, vemalization is associated with P. Chromatin modification al the FLC (FLOWERING LOCUS C) locus Q. Degradaticn of the FLC protein R. Inactivating the FLC protein by post-transtational modification S. Down-regulation of FLC transcript Was (BPS RR ©) QR Q.18. Whick of tae following statements la plaat respiration are CORRECT? P. ‘The oxidative Pentose Phosphate Pathway can accomplish the oxidation of glucase in the stroma of mitochondria Q, ATPis produced in the reaction step of TCA cycle catalyzed by succinyl CoA synthatase R. In addition to Cytochrome ¢ oxidasc. an allemative oxidase enzyme resistaat to cyanide Teduces oxygen molecule in the electron iransport system S. In Glyoxylate cycle acetyl CoA reacts with citrate to form a~keto ghutarale APR (B)P,Q (COQR DAS XL Tia 20.9 Qi9 Q.20 Study the following diagram depicting the plart cell cycle and match the following ‘Stages of cell cycle Type of eyatin P. Late Gl-phase 1. Cyclin B ‘Beginning of S-phase 2. Cyclin E R. Prior to mitotic phase "TTB. S-Cyetin S, Early Gi-phase 4 Cyclin D (AP 4.Q3,.RAG2 BPA QIRLS4 (C)PAQ4R3S2 (D)P3,Q1R2S4 In the context of plant development, which of the following statements are CORRECT? P. Cell migration is abseru Q. Apoptosis plays a majar cole R. Patter formation continues throughout life S. Homeotic changes are caused by mutatioas in non-homeodemain proteins AIP.QR QRS CHP.QS COPPRS END OF SECTION - J 1424 200 x K : MICROBIOLOGY Q.A- Q.10 carry oue mark cach. Qu Q2 Q3 Qa Qe. QS, Xt ‘An clocivon microscope has highes resolution as compared 10 the light microscope, This is because (A} the wavctength of an clectron is longer than the wavelength of light (B) the Wavelength of an electron is shorter than the wavelength of light (C) the electrons can penetrate the sample bewer (Dy chey use differem stains, Bacterial cell lysis by lysoryme is Jue to the (A) hydrolysis of ceLs-glycosidic bonds between the N-acetylghucosamine and Neacetylinuramic acid (B) inhibition of cell wall synthesis (©) hydrolysis of pentapeptide bridges (D) hydrolysis of B-l4alycosicic bonds berween the N-acetylgluccsamine and N-acetylmara acid The recombination frequencies between three genes x, y and 2 are as follows: Noy: LO%, ye: L496 and x-z: 1.2%. Then the gene order is, Ayeny @) xyz Oynz D) xy A mutant phenotype due to a nonsense mutation can be cescued by 4 mutation in tRNA gene. This rescue is an example of (A) induced mutation (B) suppressor mutation (C) spontaneous mutation (D) deletion mutation Ames test is performed to detect (A) mutigen B) pa (C)nutzient stress (D) salinity Wild type &.coff forms purple colored colonies on EMB-laclose plate. This is due to (A) increase in pH of the medium (B) cecrease in pH of the medium «C) secretion of purple colored pigment {D) sceretion of P-galactosidase The resistance of a lambda lysogenic Ecol to re-infection by lambda is mediated by (A) blocking eatzy of the incoming lambda DNA (B) degrading the incoming lambda DNA {C) blocking transcription of the incoming lambdu DNA (D) triguesing mutation of the lambda receptor of the host Pasteurization of milk is carried out by (A) boiling for 5 min (By heating 272°C for 30 min iC) heating at 63°C for 1 (Dy heating at 63°C for 30 mia 15/24 2am Qo Quo. Qu- Qu. Qi Qu3. Qua. Qs, x Be A growing bacterial culture with a doubling time of 20 min reaches cell density of 2 x 10' cells/ml in 3 hours. How much time would it take to reach the cell derisity of | x 10°cells Aml? (A) 200 min (By 180 min (C) 160 min () 90 min The quickest way to determine bacterial growth in terms of viable cells is through (A) Most probuble mumber (MPN) technique (B) Spread plats method (C) Pour plate method (D) Slide culture technique Q.20 carry two marks each. ‘Match the scientist from Group J with the corresponding contribution listed in Group II roup I Group Il P. Robe Koch 1. Discovery of endospores Q. Walter Hesse 2. Disproved spontaneous generation R. Louis Pasteur 3. Discovery of caustive agent of tuberculosis S. Ferditand Cohn 4, Use of agar as solid media 5. Invention of microscope (AP5Q3R4, (6) P-3.0-4 ©P304R4 D)P3.Q4,R-25-1 ‘Superantigens elicit a very sirong T cell response because they (A) bind to ihe specific antigen binding site on the T cell receptors (TCR) (By bind to the site on T cell receptor (TCR) that is outside the antigen-specific binding site (C)directly activate the T cell without the help of antigen presenting cells {D) directly induce cytokine secretion by macrophages MHC-I groove can be loaded with peptides of only 8-10 arnino acids because (A) MHCI groove is closed on both ends (B) fragments of only 8-10 amino acids are generated in MHC-1 bearing cells (C) Br microglobulin of MHC-I prevents the binding of large poptides to MHC-1 (D)f polypeptides of MHC-1 prevents binding of 8-10 amino acid long peptides to MCI tna lacO lac RacO” lacZ” partial diploid, of the two lacZ eneymes, only the mutant enzyme = c (lacZ) is synthesized constitutively. This observation shows tha: facO™ mutation is. (A) zans-dominant (B) rrans-recessive (C) cis-dosninant (D) cis-recessive ‘Which one of the following events occurs in prokaryotes but NOT in eukaryotes? (A) Protein phosphorytation {B) RNA polymerase and promoter interaction (C) Control of transcription by attenuation (D) Formation of Okazaki fragments 206 xt Q.L6, Match the pathogen in Group T with the corresponding disease in Group IT roupE Group P. Bacteria 4, Measles Q Viris 2. Candidiasis R. Fungi 3, Malaria, 5. Protozoa 4. Bovine spongiform encephalitis 5. Tuberculosis (ADPe1. 2, Rot, $5 (BP. Q4R2S3 (OOPS, QU, RA 8.2 (DPS, Qe, R-2, $3 QUIT. A bacterial cukure was diluted 1000 fold and 0.1 mil of this diluted sample was spread per plate on ‘wucrient agar. In a riplicate run, the number of colonies fortmed is 121, 93 and 86. The number of colony forming units/ml in the original bacterial culture is A) 106 @B) 10° (cy 108 Dy 10 QR. Match the microorganisms in Group 1 with the application in Group IL Group Group 1! P. Aspergillus oryeae 1, Metal ore leaching Q. Brevibacteriam flavin 2, Gluccamylase producer R Thiohacillus ferracidans 3, Bread making 8. Saccharomyces cerevisiae 4, Glutamic acid produces T. Rhizobium melitoti 5. Penicillin producer 6, Symbiotic nitrogen fixer (A) PHAQSR4S-5,T2 B)P2.Q4RIS3.T6 (C)P4QURGS-3.T-5 (D)P6,Q2R3S-5T Q19. A mutant of E.coli grows normally on glucose ot on glycerol but nol on acetate, The most likely metabolic pathway that is defective in this mutant is (A) Glyoxalate cycle {B) Hexose monophosphate shunt «C} Krebs eycle {D) EninerDuodoroff pathway 20. Match the resistance mechanism in Group I with the antibiotic in Group IL Group t Group It P. B-Lactamascs 1. Aminoglycosides Q. Enhanced folate metabolism 2. Penicillins R. Drug cfflux 3. Sulfa drugs S. Phosphorylation of thedrug 4. Tetracyclins T. Murant RNA polymerase 5, Naladixic acid 6 Rifamycin (A)P2.03,R4,8.5,7.6 (C)P-2.Q-,R4S-1,.T-6 BYP3.QARAS6TS {D)PA,Q2R3S-4.76 END OF SECTION - K xt Una 2010 L : Zoology Q.1-Q.10 carry one mark each. Qn Q2 03 Qt OS. Q6. Q7 Q8. XL From the perspective of developmental origin. which of the following structures is homologous to a lortoise shell? (A} Exoskeleton of a lobster &B) Bones of a fish (C) Skull of humans {D) Feathers of hinds Acoelomates are characterized by (A) the absence of cavity surrounding the internal orgens (B) the presence of huge body cavity, as in case of terrestrial animals (C) the presence of air sacs, as in case of birds (D) the absence of brain in a group ofestincr species |dentify the phylum: that is characterized by the animals that have segmented appendages (A) Chideria (03) Porifera (©) Arthropoda 1) Mollusca Which one of the following is the smaltest biological unit capable of evolving over time? (A) A cell (B) An individual organism (C) A population (D) A species In case of parasites that require mukiple hosts to complete their life cycle. what does definitive host (A) is the host that harbors the seaual stages of the parasite, (B) Is the fost in which the parasite reproduces asexually. (©) Ihis the bost in which the parasite feeds. {D) iis the host in which the parasite cemuins in ¥ dormant stage. Enaymet catalyze biochemical reactions by (A) sequestering the product(s) (B) decreasing the 8G of the reaction (©) increasing the AG of the reaction (D) stabilizing the transition state of the reaction, Which one of the following results from Mendel’s monohybrid cross is the strongest evidence against the blending theory? (A) 3:1 ratio of phenotypes in the FL generation {B) All progeny of the F generation exhibited the dominant phenotype (© The recessive phenotype showed up in the F2 progeny (D) The observation of incomplete dominance In the coatex: of cell differentiation, lateral inhibition is referred to a the (A) formation of (wo alistinet cell types within: «uniform field. ©) inhibition of formation of a distinct cell (ype next lo an existing cell type. (C) inhibition of stem cells towards self-renewal (D} inhibition of erythepoesis in the latera) plate mesoderm, 18/24 zoo Qo. O10, xL ‘As compared to peptide hormones, steroid hormones take more lime to activate a cellular response because (A) steroid hormones show non-specific binding with diverse sets of receptors. (B) steroid hormone acts through a receptor which is a (ranseription factor. «C) cells that respond to steroid hormones are dormant in nature, (D) peptide hormanes are not transported through plastna while steroid hormones are. In allopatric mode of speciation. « new species forms due 10 (A) Geographic isolation {B) Genetie drift (C) Formation of a few fertile individeals thar can not mare with other members of the same species living in the same geographical arca (D) The formation of allopelyploid condition Q.11 - Q.20 carry two marks each. Qu a2 Qu3 Q4 ‘Neurogen

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