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INSIDER’S BOOK OF SECRETS THE REAL CURES BURIED BY CLINTON'S CARTEL © Copyright 2016 by the Institute of Health Sciences, LL.C., PO. Box 913, Frederick, ‘MD 21705, All rights reserved. No part ofthis report may be reproduced by any means ‘or for any reason without the consent ofthe publisher. he information contained herein is obtained from sources believed tobe reliable, but its accuracy cannot be guaranteed. Additional orders and inquiries can be directed to the Health Sciences Institute, Mem- ber Services Department, PO. Box 913, Frederick, MD 21705; tel. (443)353-4201, fax (410)230-1273, For international orders, please dial 01-(443)353-4231., All material in this publication is provided for information only and may not be con- strued as medical advice or instruction, No action or inaction should be taken based solely on the contents of this publication; instead, readers should consult appropriate health professionals on any matter relating to their health and well-being, The informa- tion and opinions provided in this publication are believed to be accurate and sound, based on the best judgment available to the authors, but readers who fail to consult with appropriate health authorities assume the risk of any injuries. The publisher is not responsible for errors or omissions. nora Table of Contents Chapter 1 Rare Brazilian compound defeats the most devastating cancers while strengthening your immune system and vitality 1 Chapter 2: Tomorrow's Alzheimer’s drugs will do what this brain-saving herb does today Chapter 3: The NO-pills way to erase arthritis pain for good. in just seven days, 1 Chapter 4: The Key to peaceful sleep found in a natural autism therapy?.......15 Chapter 5: Keep your insides from turning to stone with this proven vitamin secret Member Source Directory Ber 29 References 30 CHAPTER ONE Rare Brazilian compound defeats the most devastating cancers while strengthening your immune system and vitality D™“” diseases—like cancer—are attacking faster than we can stop them. ‘And they're becoming ever more resistant to even the most powerful and toxic drugs... though those treatments take a devastating toll on patients desperate to survive. More and more, doctors and researchers are turning to nature to find cures for “incurable” cancers and other difficult-to-treat diseases. And they found the solutions they were looking for... in a very small area in the northeast corner of Brazil Only in Brazil Bee propolis is as common as bees themselves—every hive creates it. But the plant sources of the propolis make a big difference... and so does geography. Propolis composition varies widely around the world, even within countries. In the heart of Brazil lies a tiny region where native bees create the rarest propolis on earth: Brazilian red. And though other propolis from the same area isn’t quite as unique, the bees in this area—which is very close to the equa- tor—make some of the most distinctive and powerfully cur: you'll find. ve compounds 2 | INstDER’s Box oF Secrers: THE REAL CURES BURIED BY CLINTON'S CARTEL. With an unmatched antioxidant and isoflavone profiles, propolis from Bra- zil draws the interest of scientists around the globe—especially the red, which isn’t found anywhere else.' And that gives them unmatched disease-fighting powers... Three types of propolis brings triple cancer-fighting properties ‘There are three distinct varieties of propolis made only by bees in Brazil— green, brown, and the very rare red—so unique that they've been the subjects of dozens of studies. Their chemical makeup is different from other propolis, and from one another... and so are their extensive cancer-fighting properties. Each contains hundreds of therapeutic compounds, and some of those have been clearly identified as powerful weapons in the war against cancer: Brazilian green propolis contains a potent cancer inhibitor called artepillin- C (ARC) that takes on a particularly vicious cancer promoting enzyme known, as PAK1. Brazilian brown contains very high levels of CAPE, or caffeic acid pheneth- ylester, which thwarts many different kinds of cancer, as well as a novel com- pound called diterpene 3. Brazilian red propolis contains mainly newly discovered unique cancer- fighting compounds, including vestitol and formononetin2 ‘And though their make up is very different, all three forms of Brazilian bee propolis have been shown to effectively defeat several cancers... both in the lab and animal studies (there haven't yet been any published human trials) and in practice. “A whole medicine chest in one substance” Holistic healer Mark Kaylor gives Brazilian propolis to most of his cancer patients... and wishes he'd known about its cancer-fighting capabilities years ago. “P've treated a lot of late stage cancer patients, people whose lives were on the line. Some of my patients are still fighting, some are in recovery. But I recommended almost all of them take propolis as part of their holistic regi- men,” he said. Unlike conventional cancer treatments—chemotherapy and radiation— Research explodes Right now, there are 17 seventeen propolis studies underway, according to clinicaltrils.gov, pitting “bee glue” against everything from gingivitis to wound care to psoriasis to cancer. that seck to destroy every cancer cell, but often fail, Dr. Kaylor’s approach cen- ters on maximizing his patients’ vitality and quality of life. And that’s where Brazilian propolis comes in. Because unlike those conventional treatments.. “T've never had a patient decline when I added propolis to their treat- ment—my patients continue to do well. Maybe that's because propolis has such a broad range of compounds and actions—it's like a whole medicine chest in a single substance.” “The only effective therapeutic available” When it comes to fighting disease, you need to know exactly what you're fighting: a bacteria, a virus, a toxin, or an enzyme, And there's a dangerous enzyme called PAK-I linked with many deadly diseases... * Recurrent colorectal cane: * neurofibromatosis (a severe brain tumor disease)* * cancers with solid tumors? * brain tumors (glioblastoma)* * breast cancer” + lung cancer” + pancreatic cancer + acute myeloid leukemia® When PAKI works overtime, it helps cancer cells invade and spread. In fact, more than 70% of cancers depend on PAK\ for survival So it makes sense that a compound that can stop the enzyme could halt cancer in its tracks... which is why drug companies are in a desperate race to come up with the first drug to control PAKI. Even after 20 years of research, though, they still have nothing.’ But there is a very effective PAKI blocker... and it’s well known to corporate 4 | IssiDen’s Book oF SecRETS: THE REAL Cues BURIED BY CLINTON'S CARTEL and U.S. government researchers... though they don’t seem to want to let you know about it. Which is why HSI exposed this hidden cancer cure back in May 2013 when we uncovered a shocking government email chain where researcher wrote freely about a known treatment for a deadly PAK1 fueled cancer... propolis is the only effective therapeutic available on the market so far. ‘That's right: bees can create anti-PAKI compounds. And you'll find thi most powerful—along with many other anti-cancer compounds—in Braziliat propolis." Brazilian propolis foils deadly cancer ‘When it comes to fighting cancer, PAKI is a prime target. And nothing— at least nothing we know about so far—thwarts that destructive enzyme bette than the ARC in Bra ARC and Brazilian green have also been shown to defeat lung cancer,! Prostate cancer," colon cancer,'’ and even neurofibromatosis tumors.'¢ ian green.!™ Bur that's certainly not all it can do. CAPE, plentiful in Brazilian brown propolis, also boasts proven cancer fighting powers, and research into this special propolis is just picking up steam. So far we know that CAPE: + prevents deadly oral cancer cells from multiplying, spreading, and surviv ing, leading researchers to conclude that CAPE should be used “for treat ment of advanced oral cancer patients.””” + has a lethal impact on triple-negative breast cancer cells, stopping thei growth, and making them much more vulnerable to chemotherapy drugs!” + increases the success of conventional treatment in cases of advanced 0 resistant prostate cancer” And diterpene 3, a novel compound found only in Brazilian brown propo lis, has fifteen times the cancer-fighting a ty of other similar chemicals.” ‘Then there's Brazilian red. A recent study” of the many anti-cancer com pounds found in Brazilian red showed so much promise that it led researchers © conclude that this unique propolis “has potential to serve as an anticancer drug.” If defeating so many kinds of cancer was all Brazilian propolis could de that alone would be miraculous. But this natural “bee glue” brings hundred of health benefits... Hundreds of actions So far, we know that propolis has hundreds of beneficial actions to boost your health and well-being. And new uses are being uncovered all the time. One of the most important things Brazilian propolis can do for you is to greatly empower your immune system,” and help defeat: * influenza + inflammation” * inflammatory diseases" * gingiviti + candida?" + herpes" * re int enterococci bacteria On top of that, propolis has been proven to promote wound healing,”® block nerve pain and fight inflammation.” Ie truly is an entire medicine cabi- net in a single substance. The most powerful propolis product ever created Whether you're fighting cancer, battling disease, or hoping to strengthen your immune system, Brazilian propolis holds the key. Through our extensive HSI connections, we have located a reliable, pris- tine, potent source of green, brown, and rare red Brazilian propolis for you. This is 100% Brazilian propolis, made with absolutely no foreign materials, and the extracts are made exclusively in the U.S. using a an exclusive water based extraction process called Green Extraction™. And for the first time ever, the three are combined in a single potent prod- uct, Bee Propolis Ultimate. Since there haven't as of yet been any human can- cer trials with this Brazilian propolis blend, the proper curative dosing has not yet been firmly established. The recommended dosage for maintaining good health is one capsule per day. For more active support, it’s safe to rake up to six capsules per day in divided doses. For more information on Bee Propolis Ultimate, please turn to the Member Source Directory on page 29. CHAPTER TWO Tomorrow’s Alzheimer’s drugs will do what this brain-saving herb does today O”" out of every nine Americans over age 65 has Alzheimer’s disease... [And the odds get worse as we get older: one in three after age 85, Today, more than five million Americans struggle with the debilitating disease—but experts expect the number to more than triple by 2050. Yes, there are drugs... and we all know they don’t work. Now we know why. Even better, we know what will work—and you can have access to it right now, years before Big Pharma comes out with a much more expensive and probably much less effective version. And if you start now—while you can still read this—you may be able to avoid the terrifying decline into darkness all together. The slide starts sooner than you think The road to Alzheimer’s disease is very long—scientists now believe it starts up to twenty years before symptoms appear—but it’s not usually noticed until brain function has taken a major slide. The earliest symptoms are very similar to age-related of stress-related issues, like difficulty remembering new names, taking longer to recall basic facts, and forgetting where those keys are. But inside your brain, things may look very different from someone who just has age or stress related memory issues. 8 | InstpeR’s Book OF SECRETS: THE REAL CuRES BURIED BY CLINTON’s CARTEL ‘What's happening in your brain It starts inside your brain cells, with their inner transport system. In healthy brain cells, that transport system is very neat and orderly, organized in parallel strands, like train tracks. ‘When everything is working the way it should, nutrients and waste prod- ucts ow where they're supposed to. Bur the protein that’s meant to keep those tracks straight—a protein called rau—can go rogue. Tau is sort of like the plastic coating on wires, and once it starts to fray, things get very messy. When those tau structures collapse, they form bundles of twisted threads (technically called neurofibrillary cangles).! ‘And the cells waste products, which include beta amyloid, suddenly can’t get out. The cell does its best with clean-up duty, and randomly dumps out amy- loid, like a train running off the track. ‘That dumped amyloid clumps up, and forms plaques throughout the brain. And brain cells start to die off, causing disruptions throughout the whole brain call network. The language and memory areas of the brain shrink. And without the right intervention, cognitive loss is inevitable. Focused on the wrong problem Anyone who's ever looked into Alzheimer’s disease has heard of beta amy- loid, or amyloid plaques, the hallmark of the condition. And for decades, scientists believed these were the problem, the cause of Alzheimer’s disease... and it became the focus of mountains of research and drug development. But now we know that amyloid plaque is an effect of the real problem, a breakdown in tau. Now scientists have to change their whole way of looking at Alzheimer’s disease and cognitive decline, and new research is getting started, But there is already something that can help, a natural herb that takes on tomorrow's brain research targets today. Real hope for your future brain To be clear: There are not yet any published studies about the impact of this brain-saving herb, called andrographis, on Alzheimer’s disease in people. But the animal studies show immense promise. And the leading researchers are brimming with hope. I talked to one of them, direct from Chile, and he told me about some of the promise they're seeing, For example, a friend's father had Alzheimer's dis- ease, and suffered memory loss from one day to the next. After taking androg- raphis for one month, he began recovering some day-to-day memory. And researchers have seen some results in the clinical setting, like patients being able to read again, or remember what day it is. ‘They're now working on a clinical trial to measure cognitive changes, and have great hope—but those results won't be in any time soon. But there are animal studies, and they give us a good peek into the furure— revealing how to keep your brain from slowly declining. When we talked about the possibility of prevention, there was excitement. In animal models before the disease starts, andrographis appears to prevent memory loss. “It may be wishful thinking,” he said, “But it could happen in people, too.” Potent plant compound fixes the right problems The science here gets very technical—but the basics are pretty clear. Andrographis contains powerful plant compounds called andrographolides. And these compounds act directly on the brain chemicals and signals that keep tau (the railroad track protein) in line. ‘One study” found that andrographolide activates a very important pathway— called Wnt signaling, crucial to proper tau functioning —that often stops working properly in brain diseases like Alzheimer’s. That finding led researchers to con- clude that the andrographalide “could be used as a potential therapeutic drug,” And andrographis protects the brain in other ways as well. An animal study? found that andrographolide decreased inflammation in the brain, which helps increase communication among brain cells. But the most impressive study so far involves the very clear impact of andrographis on the brain function of lab mice. Protecting against brain cell and memory loss To really see what andrographolide could do in the brain, researchers looked at two mouse models of Alzheimer’s disease with mice aged either seven months or twelve months.* ‘The mice were given andrographolide, to see how it impacted the progres- 10 | Inster’s Book oF Secrets: THE REAL Cures BuRiEp By CLINTON’s CARTEL sion of Alzheimer’s disease. And it did have a major impact: * reduced tau breakdown + decreased harmful amyloid levels and prevented clumping + prevented disease progression + reduced cognitive impairment * decreased oxidative stress and inflammation in the brain * protected against brain cell loss + increased creation of new brain cells ‘These results indicate that andrographolide could help prevent Alzheimer’s disease progression—maybe even in people. Five brain-supporting ingredients help get your brain back on track ‘Though andrographis is the star performer in a brand new—so new it’s just now being made available—brain protective stipplement called NeuroActin®, the formula contains five additional ingredients to pack in even more brainpower. Schisandra protects your brain cells to prevent cognitive deficits. St. John’s wort can significantly improve recognition memory and spatial memory declines caused by stress.° B vitamins—B3, BG, and B12—are closely linked to cognition and aging, especially because older adults are likely to have small deficiencies in these crucial vitamins.” They're especially critical for adults with mild cognitive impairment and high homocysteine levels (a key factor in Alzheimer’s disease), according to a recent placebo-controlled clinical trial.® That study found che B vitamins slowed cognitive decline, and may even help prevent the conversion from mild cognitive impairment to dementia. Protect your brain and your memory with NeuroActin® Don’t wait until it's too late to save your precious brainpower. You can protect your memories and prevent cognitive decline with NeuroActin. ‘The manufacturer recommends taking two NeuroActin capsules per day. Keep in mind that changing the brain takes time, so allow a month or two to see the impact. For ordering information on Neuroactin, turn to the Mem- ber Source Directory on page 29. ju CHAPTER THREE The NO-pills way to erase arthritis pain for good... in just seven days Ww you wake to stiff joints and unbearable pain, knowing there’s no real relief in sight, it’s hard co even get out of bed. But you take some pain pills, grimace your way into clothes and shoes, and get started on your day. Unfortunately, that’s the normal way to start your day when you suffer from arthritis. And no matter what pain relievers you take, no matter which ones you've and they do nothing to tried, they ALL come with damaging side effec actually solve the problem. Now you have a better choice—a li hanging natural compound that qui- ets pain and eases stiffness while it begins to repair and rejuvenate your aching joints... and it's not another pill that you have to choke down. Trash or treasure It's one of the only natural compounds on earth that contains everything your body needs to build cartilage and connective tissue—that basic materi- als that form healthy, flexible, painfree joints. But in an odd twist of fate, we usually just throw it in the trash. Ever peel a hard-boiled egg? Then you have thrown this joint miracle in the garbage. Because that thin—and, honestly, annoying—film that insists on clinging when you try to peel that egg, that’s exactly where all of those crucial building blocks are held. INTON’S CARTEL, 12 | INstDeR’s Book OF SECRETS: THE REAL CURES BURIED BY ‘That film, known as eggshell membrane, contains a substantial amount of the most important structural protein your body needs: collagen. In fact, it's the number one protein in your body, coming in at up to 35% of the total. ‘With enough collagen, your body creates the strong and supple connective tendons and ligaments—that hold your bones and allowing them free and easy movement. tissues sin place, ‘And eggshell membrane naturally contains so much more than three cru- cial forms of collagen (Types I, IV, and X), such as more than a dozen amino acids, essential proteins, and healing minerals including: * glucosamine + chondroitin + hyaluronic acid * calcium, * keratan sulfate + methionine * cysteine But here’s the catch—not just any eggshell membrane supplement will do. In fact, even though they may quote the same research, they are not the same. inal NEM® eggshell membrane works like no other. First on the scene, patented NEM was subjected to extensive studies, including three robust published clinical trials. You want the ot ‘And while other brands piggyback on that rescarch, it doesn’t really apply «0 them, Because unless the eggshell membrane is processed in a specific, nutrient sparing manner, you won't be getting even close to the same quality. Unlike other products on the market, NEM is prepared using a gentle proprietary steam-based method, developed to preserve the healing nutrient content of the membrane... and that method took years of trial and error to perfect. In fact, it actually works with your digestion for optimal absorption and effectiveness. ‘And all of that care comes shining through in their clinical seudies... and in the many arthritis patients who no longer suffer excruciating pain every day. Just 500 mg of NEM a day brought on substantial improvements in pain, stiffness, flexibility, range of motion, and quality of life, And this innovative form of NEM—a delicious chewable, sort of like a very soft cherry Starburst candy—gets to work as soon as you pop it in your mouth, Range of motion pain drops 75.9% ‘The very lucky arthritis patients involved in the first NEM clinical trials enjoyed quick and sustained pain relief... despite the fact that during these two small open-label trials' they were only allowed to use acetaminophen for pain relief. And by the first check-in, on day seven of taking 500 mg of NEM daily, they understood why. And after the full thirty-day trial period in the single-arm trial, eleven arthritis patients saw: + 72.5% decrease in pain + 43.7% increase in flexibility + 75.5% reduction in range-of-motion related pain On the heels of that success, researchers ran a randomized double-blind, placebo-controlled trial? with 67 osteoarthritis patients, to see just how well ardaily dose of 500 mg of NEM worked compared to a placebo. Participants were not allowed to take any pain medication at all. Within just ten days, researchers saw pain decreased 15% more with NEM than placebo, and stiff ness decreased by 13%. And after a full sixty days using NEM, a third of the patients experienced at least a 50% reduction in pain. Most recently, an open-label clinical scudy? found that patients suffering with knee, ankle, and hip osteoarthritis enjoyed rapid and continuous pain relief with NEM. And some of the biggest improvements came in specific activities: + 35.6% pain reduction after sitting with their legs bent for a long time + 34.9% pain decrease while doing household chores + 33.6% less pain putting on socks * 32.6% pain reduction when going up and down stairs + 32.8% less pain when getting in or out of a car or bathtub ‘These real-life improvements can change your life if you've been suffering constant arthritis pain. And all three studies found that NEM works very fast, and keeps working to decrease pain and stiffness more every day. 14 | INsipeR’s Boox oF SzcRets: THE REAL Cures BURIED BY CLINTON'S CARTEL “My knees aren’t worried about it” Playing college football—and baseball and basketball—takes a toll on your body. And thirty years later, Alan Taft was feeling the consequences. “Lhad knee injuries, torn ligaments, my shoulder popped out. And as I got older, bending down or climbing up stairs brought on stabbing pain in my knees, My joint flexibility was shor,” he told me. “Whenever I needed to go upstairs, I knew the pain was coming. It would start with the first few steps, idn’t and just get worse—but I just got used to it. I was in pain, but I really want to take prescription drugs.” So Alan did a litle research, and he tried “a bunch of stuff, but none of it really worked. When it got bad, I'd mask the pain with anti-inflammarories like Aleve, but that really isn’t a longterm solution, Then I found out about NEM, and it made sense to me—at least on paper—so I decided to try it. And, luckily, I found the Redd Remedies Joint Health Soft Chews (which contain NEM). I hate to take pills, so I tried them. And they made a definite difference—really left an impression.” In just four days, Alan noticed his knees were felling better. So he kepe using the chews every day, and his mobility and flexibility kept getting better. He had less discomfort than before. And soon, he didn’t feel any pain on those first few steps. “This isn’t just a pain mask or a joint lube—this has some regenerative properties, I can perform better than I have in years. In fact, last week I was laying hardwood floors, and I was crouched in a catcher’s stance for hours. My muscles were sore, but my joints felt fine. Before the Joint Chews, that would have been impossible—I wouldn’t have been able to do it. I still have more floor to lay, but my knees aren’t worried about ir.” Joint Health Soft Chews make defeating arthritis a piece of candy If you're tired of struggling with pain and stiffness, and just as tired of tak- ing handfuls of pills, Joint Health Soft Chews solves both problems with a delicious candy-like chewable that defeats arthritis pain for good. ‘The manufacturer recommends taking one Joint Health Soft Chew daily. Turn to the Member Source Directory on page 29 for ordering information. CHAPTER FOUR The key to peaceful sleep found in a natural autism therapy? osing sleep makes everything harder: focus, concentration, not snapping I 4at your spouse. And it can be a terrible cycle: insomnia makes you more tense and anxious, and anxiety makes it harder to sleep well. Millions of us turn to sleeping pills when we just can’t take the exhaustion anymore—but those can lead us down a very dangerous... possibly deadly... path, And while these drugs will definitely knock you out, you probably won't wake up feeling rested and refreshed. In fact, chances are you'll wake up feel- ing hung over, groggy, and confused... if you were lucky enough to avoid perilous behavior while you were sleeping. On top of that, sleeping pills can’t do anything for your mood during the day. And they're well known for causing memory and cognition issues— exactly what you're trying to avoid. But there is a natural way to feel calm and focused all day, and get a solid night's sleep every night, thanks to an accidental discovery made by parents and grandparents of children struggling with autism or ADHD. Sleeping pills: Even worse than you think Honestly, the research on sleeping pills—both prescription and OTC—is thoroughly frightening. It’s baffling that these drugs continue to be approved by the FDA and prescribed by doctors who know full well the damage the pills can do... until you remember that there’s a lot of money to be made here... 16 | INstpER’s Book OF SecRETS: THE REAL CURES BURIED BY CLINTON’S CARTEL From January through June 2015 (the latest information available), Lunes- ta brought in nearly $80 million and Ambien CR sales topped $45 million... and those ate just two of the most-prescribed sleeping pills over a short six- month period. So, once again, Big Pharma and their pals at the FDA knowingly put profits over safety. In fact, a just-published study! updating information presented to the Commissioner of the FDA reported: Almost every month, new information appears about the risks of hypnotics Gleeping pill). The most important risks of hypnotics include excess mor- tality, especially overdose deaths, quiet deaths at night, infections, cancer, depression and suicide, automobile crashes, falls, and other accidents, and Iypnotic-withdrawal insomnia. The recommended doses objectively increase sleep little if at all, daytime performance is often made worse, not better, and the lack of general health benefits is commonly misrepresented in advertising. And that's just one of many studies highlighting the extreme dangers and questionable effectiveness of both prescription and OTC sleep medications. Other terrible outcomes include: + 70% increased risk of developing an autoimmune disease” + 65% increased risk of stroke? + respiratory failure and coma‘ + sleep-related eating disorder’ * traumatic brain injury and hip fracture® * premature death’ + 1,016 adverse reports already 1,016 adverse reports already The newest sleeping pill on the market, Belsomra, was FDA-approved in early 2015, and in the blink of an eye, the drug had 1,016 adverse reports filed by June 2015. Some of the worst complaints included sleep disturbances—like horrible nightmares and sleep paralysis—and suicidal depression. And on the drug's own website, it states that people should not do any activities that “require clear thinking after taking Belsomra.” li ‘The newest sleeping pill on the marker, Belsomra, was FDA-approved in early 2015, and in the blink of an eye, the drug had 1,016 adverse reports filed by June 2015. Some of the worst complaints included sleep distur- bances—like horrible nightmares and sleep paralysis—and suicidal depres- sion. And on the drug’s own website, it states that people should not do any activities that “require clear thinking after taking Belsomra.” Luckily, you don’t need to risk your life or your health to get a good night's sleep, thanks to a serendipitous discovery. When conventional medicine failed... ‘When physician and clinical researcher Dr. Hatipoglu of the Cleveland Clinic desperately needed safe and effective medicine for her child, it came up shore. “was so used to understanding a problem and finding a medical solution,” she told me. “But when I found out my son was autistic on top of having a heart arrhythmia, there was nothing in medicine to turn to, We tried every- thing: the typical interventions, occupational therapy, everything—but they all focused on changing my child’s behavior. But some things you can’t teach, and you can’t learn to change.” Ic was a heartbreaking situation. Her son couldn’t talk, or make eye contact. But, still, Dr. Hatipoglu was strongly connected to her son. As his mother, she knew when he was hungry, thirsty, or tired. But as he grew older, the problems became harder to handle—and she couldn't use any of the medi- cations available because of his heart condition, The situation felt frustrating and hopeless—but she never gave up. And then one day, she was attending a medical meeting about a new path- way for diabetes and weight loss, and got her first glimpse of a crucial body system called the endocannabinoid system—one that also had strong ties to behavior. ‘That sparked an idea—one that would lead to the creation of a patented natural therapy to help children with autism, ADHD, and other behavioral issues... and it was just the beginning. A doctor and a pharmacist cook up a solution Dr. Hatipoglu’s research led her to a naturally calming plant that had been used for generations all over the world: passionflower. And the pub- lished literature confirmed that passionflower worked along those very 18 | INSIDER'S Book OF SzcReTS: THE REAL Cures BURIED BY CLINTON'S CARTEL pathways. Excited to try it, Dr. Hatipoglu bought an over-the-counter passionflower supplement—but it didn’t do much, and she gave up. But as fortune would have it, she connected with a compounding pharmacist who knew why it hadn’t worked. “He said he was going to find me a better source,” she told me. “I never even considered shelf life issues, or the supplement source. And he did find the best source, and sent me some to try. It worked so fast, and calmed my son down, Within one week, he was making eye contact and starting to sing songs 6 Over time, the doctor and the pharmacist perfected the formula known as Neural Balance. with words. The change was dramatic—ie was amaz A unique system Passionflower works so well because it gently rebalances signals in the endo- cannal (EC) system, a series of pathways and transmissions that work like nothing else in your body. Cannabinoids are chemicals that your body naturally produces to impact how you feel, think, and react. They affect special receptors in your brain... but not in a way that scientists ever expected. You see, your brain works by sending chemical signals between brain cells to regulate everything you do. ‘Typically, a brain cell releases a chemical, that chemical travels through a gap (called a synapse), then attaches to the receptors of the next brain cell. The receiving brain cell gets the message and springs to action, and that chemical message gets passed along. The EC system, though, works backward. When the receiving brain cell gets activated, cannabinoids travel back to the sending brain cell, and attach to EC receptors there. And instead of controlling the receiver, they control the sender, acting almost like a dimmer switch to tone down the amount of brain chemicals that get released... essentially calming things down. Because of the widespread impact of the EC system, researchers have honed in on these pathways to develop new disease therapies for conditions like dia betes, obesity, osteoporosis, insomnia," and anxiety disorders.” But they con- tinue to overlook what nature has already provided, a highly safe and effective EC system moderator—passionflower. j9 Ie takes a special blend For more than 3,000 years, people have counted on passionflower to keep them calm and help them sleep—but science only recently began to catch up. A large body of evidence supports passionflower’s soothing capabilities, clearly demonstrating it’s effectiveness for treating stress, anxiety, and insom- nia! and its healing impact on a crucial brain chemical called GABA that influences relaxation.'* Now, you can find dozens of over-the-counter supplements that contain passionflower—but none with the highly effective combination in Neural Bal- ance, Not all passionflower is the same... and for it eo work properly, you need a therapeutic dose at a high enough concentration of bioflavonoids. Ic took a lot of trial and error, fine-tuning, and perseverance, but Dr. Hati- poglu and the compounding pharmacist she worked with finally discovered blend and dose of passionflower that brought the results they'd g for. Using three distinct types of passionflower, and including both flower and fruit extracts, they created the perfect mix with a high level of healing biofla- vonoids. And because original focus of Neural Balance was helping autistic children, they added some key calming nutrients: magnesium chloride from the Dead Sea, Coenzyme QU0, and vitamin B6. By gently tweaking the endocannabinoid system, Neural Balance helps settle down overexcited brain cells and nudge underactive ones, keeping a fine balance that brings a sense of calm and focus—no matter your age. Grandmother finds relief in children’s remedy Denise Coleman had never needed an antidepressant in her life. But the year she turned sixty, the unthinkable happened. “Te was an unbearable year,” she told me. “Both of my parents died, and then my daughter had a stillborn child. Everything was so hard, I was filled with despair. I couldn’t eat, I couldn't sleep. Then one day at church, a friend gave me two containers of Neural Balance to try. And things started to get berter.” Within about a week, Denise felt more in control. “I was still very sad, but I didn’t feel ike I needed to walk around with a bag on my head. I slept better, ate better. I got through everything I needed to get through. “I'm a nurse,” 20 | INstDER’s BOox oF SECRETS: THE REAL CURES BURIED BY CLINTON'S CARTEL she continued. “And I wouldn’t have hesitated to take an antidepressant if 1 needed it, but this really worked.” Passionflower is approved as a drug in Germany, deemed safe for children and pregnant women. Neural Balance worked so well for Denise that she thought it could help her two grandchildren, both of whom had tried taking Ritalin for focus and behavior issues. “They're both off Ritalin now—those late day meltdowns when the drug left their body were so difficult, and it really messed with their appetites. But after they started taking Neural Balance, their parents got notes home from teachers asking what was different at home. My granddaughter was now participating and focused, my grandson wasn’t stirring up trouble. My granddaughter calls it her brain juice.” “As for me,” she said, “it helped me sleep a lot berter, and it helped me stay asleep. I was so tired, emotionally tired, and I would finally fall asleep, but I would wake up and couldn’t get back. Now, I sleep.” Neural Balance: The safe way to get a good night’s sleep Don’t turn to dangerous drugs to help you fall asleep at night. Neural Bal- ance helps you fall asleep, and stay asleep, without risking your health or your life, And for those days when stress and anxiety are getting the better of you, Neural Balance restores your sense of calm focus. ‘The manufacturer recommends mixing a one-teaspoon scoop of Neural Balance into 4 to 8 ounces of cold water. (It comes with a convenient scoop in the container.) Most users benefit from two servings per day, one in the morning and one in the evening. For extra support, you can take up to four servings per day. ‘Anote: Since Neural Balance was originally designed for kids, it does taste sweet and fruity, but it does not contain any sugar. For ordering information on Neural balance, turn to the Member Source Directory on page 29. Ja CHAPTER FIVE Keep your insides from turning to stone with this proven vitamin secret ye could be doing everything right: eating healthy, exercising, watching your blood pressure, perfectly managing your cholesterol and blood sugar. But you're still facing a very high chance of fatal heart attack. All because of a hidden risk factor so subtle you won't feel a thing until it’s too late. But if you take steps now to protect yourself from this insidious foe, with the only proven solution, you can stop—maybe even reverse—its progress... Before it kills you. The most deadly secret Meet Joe and Bob, two guys in their mid-sixties. Joe works out a few times a week and eats a super healthy diet—mostly chicken, fish, and vegetables. His blood pressure, cholesterol, and blood sugar are firmly under control. But he has the hidden tisk factor... he just doesn’t know it. Bob is a meat-and-potatoes guy all the way. The closest he gets to exercise is watching football, and it shows. His weight, blood pressure, and choles- terol levels drive his doctor crazy and his wife to nagging, and his blood sugar runs dangerously close to diabetes. And, unlike Joe, Bob doesn’t have the hidden risk factor. If you had to guess who was more likely co suffer a fatal heart attack, 22 | INsipeER's BOOK OF SecReTS: THE REAL CURES BURIED BY CLINTON'S CARTEL you'd probably pick Bob—almost everyone would. But with that hidden risk factor, Joe is much more likely to die... soon. Many of us will turn to stone Sounds crazy, but it’s 100% true. As we head into our 60s and beyond, many of us have started turning to stone... we just don’t know it, or feel The slow process of calcification—where unwanted calcium deposits build up in your blood vessels, organs, and soft tissue, literally hardening your body from the inside out—impacts so many of us... * A study! of 577 adults aged 55-86 found that more than half had calci- fication, and the severity increased with age. * A study” in China that included 10,305 older adults, average age of 65, found that more than 40% had calcification. * Avery large study* of 44,052 people found that among healthy subjects without any risk factors for heart disease, 48% had some level of calci- fication. And it’s even worse for people already struggling with diabetes or kidney disease.* Bur it can be stopped, maybe even reversed... If you start addressing it right now, before your calcification takes a fatal urn. Essential mineral turns deadly You need calcium to survive. And your body needs a very specific amount circulating in your bloodstream—so if you aren't taking in enough from food and supplements, it will steal calcium from your bones, But it’s not enough to consume enough calcium. You also have to be able to process it properly, and here’s where things turn tragic. When your body can’t use calcium the right way, to shore up your bones, you begin to suffer from bone loss and osteoporosis. ‘Ac the same time, the calcium that’s not getting into your bones starts depositing in your blood vessels and soft tissue—where you absolutely don’t want it.’ That's called calcification, and it can make your blood vessels so stiff that healthy blood flow to your heart gets blocked. [23 Ie’s the calcium paradox: your bones get too little calcium at the same time that your organs and arteries get too much... setting you on a deadly path. Heart failure and death Too often, heart failure is the first sign that calcification has taken hold. In fact, calcification alone is closely linked with heart failure... and death. In one study,* 1,897 older adults with no known symptoms of heart dis- ease had their calcification levels measured at the start, and were followed for nearly seven years. And the people with higher levels suffered a much higher incidence of heart failure—nearly four times higher than people with very low or no calcification. Another study’ showed that higher calcification levels were strongly asso- ciated with coronary heart “events, ” including heart failure and death, in 10,746 people with no cardiac risk factors or symptoms. Most alarming, this trend held true for people under age 40. One very large study’ that followed 44,052 adults with no symptoms and no existing coronary heart disease found rruly frightening results. People with high calcification levels and no risk factors (such as smoking, high blood pressure, diabetes, high cholesterol, and family history of heart dis- ease) faced seven times the chance of premature death than people with low levels and three risk factors. Another look at thar large study also showed that high blood pressure sends the risk level sky high. Subjects with the lethal combination of high blood pressure and calcification had the highest fatality rate of all.® And the opposite is true as well: A brand new U.S. study? of 13,092 What the numbers mean Ideally, your calcium score would be zero, indicating very litte risk of heart attack in the next two to five years, As the score increases so does the risk. Scores of 400 or more indicate concerning calcium buildup, and a substantially increased risk of heart attack in the next ten years. A score of 1000 or more means you have a 25% of having a heart attack within one year, and must take immediate steps to avoid that tragedy. ‘Age plays a part here, too. A safe score at age 80 could be a fatal score at age 40. 24 | Insiver’s Book oF SecreTs: Tae Reat Cures BURIED BY CLINTON'S CARTEL people showed thar death rates of older adults with no calcification was sub- stantially lower than the general population. Know the score Ir may be the most important number you'll ever know: your CAC score. ‘The CAC measures coronary artery calcification, and it’s eerily accurate for predicting your risk of heart attack and premature death. The higher your CAC, the more danger you face—even if otherwise you're the picture of perfect health. ‘The CAG, also known as the Calcium Score or the Agatston Score, ranges from zero—for no calcification at all—into the thousands. And scores great- er than 400 are considered very high risk, regardless of your age or any other risk factors. The test to determine the score calls for a simple, non-invasive CT scan—and knowing your score can save your life... especially if you have no obvious risk factors for heart disease. If your score signals danger ahead, you can start taking immediate steps to stop the calcification progress. You can ensure that calcium goes where you want it to, and stays out of your soft tissue where it wreaks that deadly damage... with a new heart- saving supplement called Artery Strong. The only way to thwart calcification If you want co ensure full blood flow to your heart and keep your arteries from turning to stone, you need the only substance that can do it: vitamin K2, and not just any form will do. Along with the right kind of K2, you need two other vitamins that it can’t work without: vitamin A and vitamin D3. And while all three are important, vitamin K2, in a special form known as MenaQ7, is the most crucial for stopping calcification. Now you may think you can get this in any old multi-vitamin, but you can’t. Most don’t contain K2... or true vitamin A... or enough D3. And, together, these three simple but powerful nutrients can do what nothing else can: thwart calcification. Fortified with these three essential fat-soluble vitamins found in Artery Strong, your cardiovascular health will improve dramatically, your blood 25 vessels will stay strong and flexible, and your calcium stores will be used the right way... maintaining strong bones. You need all three Each of these vitamins plays a key role in cardiovascular health—though K2 seems to be the most important for keeping calcium where it belongs. But even powerful K2 can’t do its most important task without A and D. Most vitamins these days contain beta-carotene rather than the activ form of vitamin A—retinol. Now beta-carotene converts into vitamin A in your body, or at least it’s supposed to, but that system isn’t always perfect. To make sure you're actually getting the vitamin A you need, Artery Strong, contains straight retinol, no conversion required. Some key jobs only retinol can do include: * keeping vitamin D in balance + regulating special proteins involved in new cell production, including cells that line your blood vessels * significantly lower your five-year risk of death from cardiovascular disease" In addition, vitamins A and D seem to work together for improved cell communication—especially in cells tied to calcium regulation. And it curns out that patients with coronary artery disease have significantly lower blood levels of vitamins A and D than healthy people." Vitamin D3 helps manage calcium absorption, and is critical for main taining bone density. It’s also used to strength the walls of your blood ves- sels, keep your blood pressure in check, and strengthen cells in your heart muscle. Coumadin works against K Many people with cardiovascular issues take a drug called warfarin (also known as Coumadin}—a drug that has the unfortunate side effect of increasing blood ves- se! caleification by blocking vitamin K.® Some studies have indicated that tiny doses of K2 can help reduce that risk, and help keep coagulation markers more stable. but only under the guidance of an experienced cardiologist. Patients taking warfarin should not take vitamin K without consutting their doctors. 26 | Inster’s Book oF Secrets: THe REAL Cures Buriep By CLINTON’s CARTEL And then there's K2... K is the key ‘There's no doubt about it: vitamin K2 is the key to stopping calcification. Studies show that people with vitamin K deficiency—low K status—are more likely to develop calcification." One Italian study" found that “important proportions” of patients were vitamin K deficient, and that an MK-7 deficiency was closely linked with calcification of the iliac arteries—the vessels that bring blood from your heart to the whole bottom half of your body. So getting enough K2 can turn that around... as long as there's also enough D. K and D together In order for K2 and D to work their best, they need to be together. ‘That's especially important for calcium management. Together, these two essential nutrients keep calcium where it belongs—in your bones.'* But neither can do that alone. Vitamin D plays a crucial role in producing osteocalcin, a protein that lets fresh calcium into your bones... but osteocalcin needs to be activated by K2 before it can lock that calcium in place. Without enough vitamin D, there wouldn’t be any osteocalcin to activate—so these two nutrients must work rogether to keep calcium from running wild, On top of thar, a 2015 study" indicated that vitamins D and K together offer protection against cardiovascular disease and premature death. Which K matters When it comes to fighting deadly calcification with vitamin K2, the right form is crucial. Relief from rheumatoid arthritis MK-7 also brings much-needed relief to rheumatoid arthritis patients. A new clinical trial shows the vitamin reduces inflammation markers and reduced RA ‘symptoms. \27 ‘The two forms commonly used in supplements are MK-4 and MK-7... and the one you want is lucky 7, superior in every way. One clinical trial!” directly compared both forms of K2, in single doses and over a seven-day period. MK-7 was well absorbed, and was still detected a full 48 hours after the single dose, while MK-4 couldn't be detected at all. And even after a week of MK-4 supplementation, there was no sign of the vitamin in the subjects’ blood... but MK-7 levels increased substantially for all subjects taking it. In fact, it cakes just micrograms of MK-7 to improve vitamin K status. ‘And you'd need a thousand times that to see a bump using MK-4 In fact, a 2015" study found that supplementing with daily wich MK-7 for three months substantially improved vitamin K status. And more K is exactly what you need to stop coronary artery calcification, CAC. The MK-7-CAC connection ‘When it comes to stopping CAC, MK-7 has a very strong track record. A three-year double-blind placebo controlled clinical trial!” found that MK-7, specifically MenaQ7?—the exact form found in Artery Strong—sig- nificantly improved arterial stiffness in healthy older women... especially in women with the stiffest blood vessels. Of the 244 healthy postmenopausal women participating in the study, 120 received 180 mcg of MenaQ7 daily. ‘And those women had unprecedented improvements in the flexibility of their arteries—crucial for cardiovascular health. And a brand new animal study" confirms that high-dose MK-7 reduces cardiovascular calcification. Now, there’s an ongoing clinical study” looking into how well MK-7 works to reverse—or at least slow down—CAC progression in patients with existing coronary artery disease and CAC scores between 50 and 400. If it works as expected, researchers will have verified the best treatment for vascular calcification: vitamin K2, the starring ingredient in Artery Strong. Artery Strong stops calcification before it destroys you ‘The time to stop calcification is right now, before it progresses to a fatal degree—and Artery Strong contains exactly what you need to make sure calcium stays out of your blood vessels. 28 | INSIDER'S BOOK OF SECRETS: THE REAL CuRES BURIED BY CLINTON'S CARTEL ‘The manufacturer recommends taking one Artery Strong sofigel daily. To order Artery Strong, turn to the Member Source Directory on the next page. ‘These are all fat-soluble nutrients, so it's best to take them along with some healthy fats. “Unhealthy” K2 foods There's a reason most people—especially people who worry about heart dis- ease—don't get enough vitamin K2 through diet... the foods naturally high in this nutrient are considered unhealthy. Some of the richest sources of K2 include: * cheese * egg yolks * chicken livers * ground beef * butter... Foods that anyone trying to cut down on fat and cholesterol will certainly avoid. Member Source Directory Artery Strong™, Terry Naturally Vitamins, Ph. (866) 807-2731; www. Terry llyVitamins.com. Artery Strongcosts US $31.95 (plus ship- ping) for 60 sofigels Joint Health Soft Chews, Redd Remedies, Tel: (888) 453-5058; wwwreddremedies.com. One 30-count bag of Joint Health Soft Chews costs US$28.99. For ordering information outside the U.S. please e-mail orders@reddremedies.com. NaturaNectar Bee Propolis Ultimate™, NaturaNectar, PH: (800) 609- 7794; www.naturanectar.com. Bee Propolis Ultimate costs US$87.99 plus shipping for a 60-day supply. Neural Balance, Spectrum Research Group, Tel: (844) 914-4357; www. om. One 60-serving bottle of Neural Balance costs US$64.95. NeuroActin®, Herbal Ultra Corporation, PH: (800)200-4180; www.herbalultra.com. One bottle of NeuroActin costs US$49.95. 30 | Instnen’s Book oF Srcrets: THe REat Cures BURIED ny CLINTON'S CARTEL Ocala) Rare Brazilian compound defeats the most devastati strengthening your immune system and vitality ig cancers while 1. Machado BA\,2, et al., Chemical Composition and Biological Activity of Extracts Obtained by Supercritical Extraction and Ethanolic Extraction of Brown, Green and Red Propolis Derived from Different Geographic Regions in Brazil. PLoS One, 2016 Jan 8511(1):e0145954. 2. Freires IAI, de Alencar $M2, Rosalen PL A pharmacological perspective on the use of Brazilian Red Propolis and its isolated compounds against human diseases. Fur ] Med Chem. 2016 Mar 3;110:267-79. 3. Al-Maghrabi Jl, et al., Overexpression of PAK-1 is an independent pre~ dictor of disease recurrence in colorectal carcinoma. Int J Clin Exp Pathol. 2015 Dec 1;8(12):15895-902, eCollection 2015. 4, Brems Hi, Beert E, de Ravel T, Legius E. Mechanisms in the pathogenesis of malignant tumours in neurofibromatosis type 1. Lancet Oncol. 2009 May;10(5):508-15, doi: 10.1016/S1470-2045(09)70033-6. 5, Fang Fl, et al., p21-activated kinase 1 (PAK1) expression correlates with prognosis in solid tumors: A systematic review and meta-analysis. 2016 Mar 24, doi: 10.18632/oncotarget.8320, (Epub ahead of print] 6. Aoki H1, Phosphorylated Paki level in the cytoplasm correlates with shorter survival time in patients withglioblastoma. Clin Cancer Res. 2007 Nov 15;13(22 Pt 1):6603-9, Senapedis W1, Therapeutic Potential of Targeting PAK Signaling, Anti cancer Agents Med Chem. 2015;16(1):75-88. 8. Pandolfi Al, et al, PAK! isa therapeutic target mia and myelodysplastic syndrome. 2015 Aug 2 10.1182/blood-2014-12-618801. Epub 2015 Jul 13 9. Kumar R1, Li DQ PAKs in Human Cancer Progression: From Incep: tion to Cancer Therapeutic to Future Oncobiology. Adv Cancer Res. 2016;130:137-209. doi: 10.1016/bs.acr.2016.01.002. Epub 2016 Feb 23. 10. Patel $ Emerging Adjuvant Therapy for Cancer: Propolis and its Constitu- ents, J Diet Suppl. 2016;13(3):245-68. acute myeloid leuke- 126(9):1118-27. doi: 11. Maruta H Herbal therapeutics that block the oncogenic kinase PAK. a practical approach towards PAK1-dependent diseases and longevity Phytother Res. 2014 May;28(5):656-72, [31 ieiale ty 12, Nguyen BCL, Artepillin C and Other Herbal PAK1-blockers: Effects on Hair Cell Proliferation and Related PAK1-dependent Biological Function in Cell Culture. Phytother Res. 2016 Jan;30(1):120-7. doi: 10.1002/ptr. Epub 2015 Nov 4. 13, Frién-Herrera Y1, et al, Brazilian green propolis induced apoptosis in human lung cancer A549 cells through mitochondrial-mediated pathway J Pharm Pharmacol, 2015 Oct;67(10):1448-56, 14, Saliszka E1, Zydowicz. G, Mizgala E, Krol W. Artepillin C (3,5-dipre- nyl-4-hydroxycinnamic acid) sensitizes LNCaP prostate cancer cells to TRAIL-induced apoptosis. Int J Oncol. 2012 Sep;41(3):818-28. doi 10,3892/ijo.2012:1527. Epub 2012 Jun 25. 15, Shimizu K1, et al., Artepillin C in Brazilian propolis induces G(0)/G(1) arrest via stimulation of Cip|/p21 expression in human colon cancer cells. Mol Carcinog. 2005 Dec;44(4):293-9. 16, Messerli SMI, et a., Artepillin C (ARC) in Brazilian green propolis selectively blocks oncogenic PAKL signaling and suppresses the growth of NF tumors in mice. Phytother Res. 2009 Mar;23(3):423-7. doi: 10.1002/ ptr.2658, Kuo YY1,2,3, et al, Caffeic Acid phenethyl ester is a potential therapeu tic agent for oral cancer. Int J Mol Sci. 2015 May 12;16(5):10748-66. doi: 10.3390/ijms160510748. 18, Rzepecka-Stojko Al, et al., Caffeic Acid phenethyl ester and ethanol extract of propolis induce the complementary cytotoxic effect on triple- negative breast cancer cell lines. 2015 May 20;20(5):9242-62. dot: 10.3390/ molecules20059242. 19. Motawi TKI, et al., Could Caffeic Acid Phenethyl Ester Expand the An titumor Effect of Tamoxifen in Breast Carcinoma? Nutr Cancer. 2016 Mar 23:1-11. [Epub ahead of print] 20, Liu CCI, et al., Caffeic acid phenethyl ester as an adjuvant therapy for advanced prostate cancer. Med Hypotheses. 2013 May;80(5):617-9. doi: 10.1016/j.mehy.2013.02.003. Epub 2013 Feb 23, 21, Tazawa S, et al, Discovery of a Novel Diterpene in Brown Propolis from the State of Parana, Brazil. Nat Prod Commun. 2016 Febs1 (2):201-5. 22, de Mendonga ICI, et al, Brazilian red propolis: phytochemical screen- 32 | INstper’s Book oF Secrets: THe REAL Cures BURIED By CLINTON'S CARTEL caer) ing, antioxidant activity and effect against cancer cells. BMC Complement Altern Med. 2015 Oct 14;15:357. 23. Gao W1, et al., Brazilian green propolis improves immune function in aged mice. J Clin Biochem Nutr. 2014 Jul;55(1):7-10. 24. Shimizu TI, et al., Anti-influenza virus activity of propolis in vitro and its efficacy against influenza infection in mice. Antivir Chem Chemother. 2008;19(1):7-13. Franchin MI, et al, Vestitol Isolated from Brazilian Red Propolis Inhibits Neutrophils Migration in the Inflammatory Process: Elucidation of the Mechanism of Action. J Nat Prod. 2016 Mar 3. [Epub ahead of print] 26. Bueno-Silva B1, et al., Brazilian Red Propolis Attenuates Inflammatory Signaling Cascade in LPS-Activated Macrophages. PLoS One. 2015 Dec 14;10(12):e0144954. Anauate-Netto Cl, et al., Randomized, double-blind, placebo-controlled ical trial on the effects of propolis and chlorhexidine mouthrinses on gingivitis. Braz Dent Sci. 2014;17(1):11-15. 28. Freires IA1, et al, Chemical composition and antifungal potential of Bra- zilian propolis against Candida spp. J Mycol Med. 2016 Feb 22. pii: S1156- 5233(16)00007-X. 29, das Neves MV1, et al,, Isoflavone formononetin from red propolis acts as a fungicide against Candida sp. Braz J Microbiol. 2016 Jan- Mar;47(1):159-66. 30. Pippi B1, et al., In vitro evaluation of the acquisition of resistance, anti fungal activity and synergism of Brazilian redpropolis with antifungal drugs on Candida spp. J Appl Microbiol. 2015 Aprs118(4):839-50. 31, Sartori G1, et al., Protective effect of brown Brazilian propolis against acute vaginal lesions caused by herpes simplex virus type 2 in mice: involvement of antioxidant and antiinflammatory mechanisms. Cell Biochem Funct, 2012 Jan;30(1):1-10. 32. Pimenta HCL, et al, In vitro effectiveness of Brazilian brown propo- lis against Enterococcus faecalis. Braz Oral Res. 2015;29. pii: $1806. 83242015000100255. 33, Jacob Al, et al., The effects of Malaysian propolis and Brazilian red propolis on connective tissue fibroblasts in the wound healing process. leary 34. Lima C: BMC Complement Altern Med. 2015 Aug 25;15:294. cendish RI, et al, Antinociceptive and anti-inflammatory effects of Brazilian red propolis extract and formononetin in rodents. J Ethno: pharmacol, 2015 Sep 15;173:127-33. ‘Tomorrow's Alzheimer's drugs will do what this brain-saving herb does today Lonskaya I, et al. Tau deletion impairs intra cellular B-amyloid-42 clearance and leads to more extracellular plaque deposition in gene transfer models. Molecular Neurodegeneration. 2014. Tapia-Rojas C et al, “Andrographolide activates the canonical Wnt signal- Jing pathway by a mechanism that implicates the non-ATP competitive in: hibition of GSK-3B: autoregulation of GSK-36 in vivo” Biochemical Journal, vol. 466, no. 2 (March 2015): 415-30. Chan $1, Wong WS, Wong PT, Bian JS. Neuroprotective effects of an- drographolide in a rat model of permanent cerebral ischaemia. Br J Phar ‘macol, 2010 Octs161(3):668-79. Serrano FG et al, “Andrographolide reduces cognitive impairment in young and mature AbetaPPswe/PS-1 mice” Molecular Neurodegeneration, vol. 9, no, 1 (December 2014): 61 Xu X, Zhou X, Zhou XW, et al. 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Clin Interv Aging. 2009;4:235-40. Epub 2009 Jun 9. Ruff KJ', Winkler A, Jackson RW, DeVore DP, Ritz BW. Eggshell membrane in the treatment of pain and stiffness from osteoarthritis of the knee: a ran- domized, multicenter, double-blind, placebo-controlled clinical study. Clin Rheumatol. 2009 Aug;28(8):907-14. doi: 10.1007/s10067-009-1173-4. Epub 2009 Apr 2, Danesch U, et al, NEM” Brand Eggshell Membrane Effective in the ‘Treat ment of Pain Associated with Knee and Hip Osteoarthritis: Results from a Six Center Open Label German Clinical Study. J Arthritis. 2014; 3:136. ‘The key to peaceful sleep found in a natural autism therapy? 1 9 Kripke DF'.Hypnotic drug risks of mortality, infection, depression, and cancer: but lack of benefit. F1000Res. 2016 May 19;5:918. Kok VC", et al, Risk of Autoimmune Disease in Adults with Chronic In- somnia Requiring Sleep-Inducing Pills: A Population-Based Longitudinal Study. J Gen Intern Med. 2016 Apr 29. [Epub ahead of print] Petrov ME’, et al., Over-the-counter and prescription sleep medication and incident stroke: the REasons for Geographic and Racial Differences in Stroke study. J Stroke Cerebrovasc Dis. 2014 Sep;23(8):2110-6. Vukcevié NP, et al., Benzodiazepine poisoning in elderly. Vojosanit Pregl 2016 Mar;73(3):234-8, Komada Y’, et al., Comparison of clinical features between primary and drug-induced sleep-related eating disorder. Neuropsychiatr Dis Treat. 2016 May 26512:1275-80. Tom SE’, et al., Nonbenzodiazepine Sedative Hypnotics and Risk of Fall Related Injury. Sleep. 2016 May 1;39(5):1009-14. Kripke DF'*. Mortality Risk of Hypnotics: Strengths and Limits of dence. Drug Saf. 2016 Feb;39(2):93-107. PACHER P, BATKAI S, KUNOS G. ‘The Endocannabinoid S: as an Emerging Target of Pharmacotherapy. Pharmacological reviews. 2006;58(3):389-462. doi:10.1124/pr.58.3.2 Bortolato M’; et al., Anxiolytic-like properties of the anandamide trans port inhibitor AM404. Neuro-psychopharmacology. 2006 Dec;31(12):2652- tem |35 cate) 1. 12. 15, 9. Epub 2006 Mar 15. Jawna-Zboitiska K’, et al., Passiflora incarnata L. Improves Spatial Mem ory, Reduces Stress, and Affects Neurotransmission in Rats. Phytother Res. 2016 May;30(5):781-9. Ngan A’, Conduit R. A double-blind, placebo-controlled investigation of the effects of Passi-flora incarnata(passionflower) herbal tea on subjective sleep quality. Phytother Res. 2011 Aug;25(8):1153-9. Lolli LF', etal, Possible involvement of GABA A-benzodiazepine recep- tor in the anxiolyt-ic-like effect induced byPassiflora actinia extracts in mice. J Ethnopharmacol. 2007 May 4;111(2):308-14. Krenn L!. [Article in German] [Passion Flower (Passiflora incarnata L.)-a reliable herbal seda-tive]. Wien Med Wochenschr. 2002;152(15-16):404-6. Kaviani N’, et al, The efficacy of passiflora incarnata linnaeus in reduc- ing dental anxiety in patients undergoing periodontal treatment. J Dent (Shiraz). 2013 Juns14(2):68-72. 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