Radionuclides

Face Biosafety Product

Type Airflow Pattern and Toxic
Velocity Levels Protection
Chemicals
• Plena are under negative
Ducted Fume
80-120 pressure to room Yes 1 no
Hood
• Exhaust is ducted to outside
• Plena are under negative
pressure to room
Ductless
80-120 • Exhaust is filtered through Mild chemical use 1 no
Fume Hood
HEPA filtration and charcoal
filtration
• Exhaust is ducted to ventilation
Canopy hood 25-60 • May or may not be return air No none no
plenum
• Exhaust is ducted to ventilation
• Material should be no more
Snorkel 80-120 Mild chemical use none no
than 4 inches away from the
cone
Laminar Flow • Clean activity dust mitigation
- None none yes
Hood
• Clean room activity dust
Clean Bench - None none yes
mitigation
Comparison of Biological Safety Cabinets

Face Radionuclides
Biosafety Product
Type Velocity Airflow Pattern and Toxic
Levels Protection
(lfpm)* Chemicals
Class I • In at front, rear and top through HEPA
No 2,3 No
Open Front filter
Class II
Type A • 70% recirculated through HEPA;
75 No 2,3 Yes
exhaust through HEPA
Type B1 Yes
• 30% recirculated through HEPA;
100 (Low levels or 2,3 Yes
exhaust via HEPA and hard-ducted
volatility)
Type B2 • No recirculation; same as IIA, but plena
100 are under negative pressure to room Yes 2,3 Yes
and exhaust is ducted
Type B3 • Same as IIA, but plena are under
100 negative pressure to room and exhaust Yes 2,3 Yes
is ducted
Class III • Supply air inlets and exhaust through
N/A None 2,3 Yes
two HEPA filters.
*Linear feet per minute